Protein Alignment brv2 and brv3

DIOPT Version :9

• Sequence 1: NP_648970.2
• Gene: brv2 / 39932
• FlyBaseID: FBgn0036712
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_001284831.1
• Gene: brv3 / 31246
• FlyBaseID: FBgn0040333
• Length: 750
• Species: Drosophila melanogaster
• Alignment Length: 736
• Identity: 303/736 - (41%)
• Similarity: 465/736 - (63%)
• Gaps: 29/736 - (3%)

  Fly    14 FGVTTCVVMVCFVLVSIFSGFMHEPQRFKTMLVTIVLVFFFQYLILEPIRFFIQSIDYATWPQE- 77
            |.:|..:::.|.:.:::|:||.||..:||||||:||:|..||:||.:||:|.|.|||.|.||..
  Fly    11 FAITVGIIIGCMICIAVFAGFQHEDVKFKTMLVSIVIVLIFQFLIGDPIKFVILSIDRALWPPRI 75

  Fly    78 --DPPYRAEEGGPTMDHIGYLKIRLRSLRSELLISEGHTNEMLNQKYKHIAGDLLLYGSYFIALM 140
              .|....:|.....:...:||.||.:.|:.|:::..:.|..||.:||.||.||.:||.||:.||
  Fly    76 YIPPRCDKDEMDEKEERRDFLKQRLINKRANLMLTSRYRNYKLNDQYKMIAHDLFIYGPYFLCLM 140

  Fly   141 LMVVLQEDHTNYYNTNNMQRLFWDNTSVTFGLSQVYFIYQVHSYMKITLVEAFYAQKT-NGYEGW 204
            .:|::..|.|.|:||..:..||..|.:...||.:|||:.|:..:::.|||.||.:..| :|..||
  Fly   141 CLVLVTRDQTLYHNTRIITDLFMYNHTDYTGLQEVYFLNQLFDFIESTLVLAFNSNSTESGSPGW 205

  Fly   205 WAMEQWQKIGVVRLRQMRPVDCHIGLGKPEWDKKTYAPEWRLPYHRMHYTEKFWRIYDPFVPAEF 269
            ...||...:||:||||:|..:..:|||.|::....|.|:|:|||.::||::|:||||:|::|.:.
  Fly   206 AHAEQSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKM 270

  Fly   270 EPSFLNGLLLNYDHYGYLLNYPEVAGYVVLMMSTKINCLKQIEYLRDYSWLDKNTSALFIDLTMY 334
            ...||:.||:|:||.|.|.:|||:||||.|:..:..|.:|.|:||.:..||..||||:|||.|:|
  Fly   271 GFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLY 335

  Fly   335 NADANLFTLITLRVENSPFGIQLPRVHVDSVSMLGNVETRSNSELLILFVYTVLVILFARGVFTK 399
            |.|.|||::.|||||.:|||..:|.|.|||..:|.||:....:.||.|.:|.::.|.||:.:..|
  Fly   336 NVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVK 400

  Fly   400 IWHHPAAAHEAWTMVDLAIYILNVFLTVLAIMRDIETDALLQIIETATKGQYLDFQRPLRLHQML 464
            :|:.|......|..:||.|:::||.:.||.::|:....::::.:|.|:|.:::||:||.|:||:.
  Fly   401 LWYEPHLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGASKMEFIDFRRPSRMHQLT 465

  Fly   465 FIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIGITLAVPNGNNA 529
            .|..|||:||||||||:||||||||:.||:||:.||.||||..:.|::.|:.....:...|||.:
  Fly   466 TITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCFAVVTINGNYS 530

  Fly   530 VVFSHMVQSVVTCMWYSMGFNGDIHPADFFHGGRILGILLYLALVFLLAIILMNVFASVIYDYFN 594
            ..|:.:|:|:|.||.||.||:..:.|::.||||:.||||.|..|.|::.::|:|||.|:|.|||.
  Fly   531 SNFNKLVKSMVMCMCYSFGFSAQVKPSELFHGGKWLGILCYGVLAFVIIVLLINVFVSLINDYFT 595

  Fly   595 ETSRILKEHSNRSSITFLEFLHVEYADLFGDAFR---CLRKTYESRGHTVAENVELEL---NRRE 653
             .::.:::....:.|||.|||.||::.:.| .||   |.|:.|...|.||||||..:|   :|:.
  Fly   596 -VAKTIRDSERENRITFFEFLVVEFSGVLG-RFRKLPCWRRNYVRNGRTVAENVSRKLDSMDRQR 658

  Fly   654 LIKFK----RDLIKSPQELKRALLTEEQRSADYRLRGEKLFKLMAILNLQVEILERMVLGDKDGK 714
            |::.:    |..:..|...:.|||       :|:.||:|:..:..|||:|:.:: ||.|.|:..:
  Fly   659 LMRRRLRQGRHHVSRPVSAEDALL-------EYKDRGDKMVNVHYILNIQLTLI-RMFLFDEYVE 715

  Fly   715 LP-----TPPASDSDPDDMPE 730
            .|     .|.|.|.||:..|:
  Fly   716 WPQEQQKQPEAQDPDPNLGPD 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv2	NP_648970.2	PKD_channel	169..596	CDD:285288	192/427 (45%)
brv3	NP_001284831.1	PKD_channel	170..595	CDD:285288	191/424 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S9099
OMA	1	1.010	-	-		QHG46093
OrthoDB	1	1.010	-	-		D1276906at2759
OrthoFinder	1	1.000	-	-		FOG0016837
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.810