Protein Alignment brv2 and pkd1l3

DIOPT Version :9

• Sequence 1: NP_648970.2
• Gene: brv2 / 39932
• FlyBaseID: FBgn0036712
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: XP_017949004.2
• Gene: pkd1l3 / 101734692
• -ID: -
• Length: 1080
• Species: Xenopus tropicalis
• Alignment Length: 670
• Identity: 151/670 - (22%)
• Similarity: 264/670 - (39%)
• Gaps: 148/670 - (22%)

  Fly    23 VC-FVLVSI--FSGFM-------HEPQRFKTMLVTIVLVFFFQYLILEPIRFFIQSID------- 70
            || |||::|  ||.:.       ...|:..:.|::::|..|....:|.|::.|||::.
 Frog   471 VCWFVLLAISSFSAYYMTLVSLDMTRQKATSWLISMLLSLFHSLFLLPPVKAFIQTVFMFRVLRR 535

  Fly    71 ------------------YATWPQ---------EDPPYRAEEGGPTMDHIGYLKIRLRSLRSELL 108
                              :|..|.         :||.|.:    |....|..||
 Frog   536 STMDDAAEEQQLHGILSLFANCPDWELSGCRDPQDPIYCS----PVNKAITSLK----------- 585

  Fly   109 ISEGHTNEMLNQKYKHIAGDLLLYGSYFIALMLMVVLQEDHTNYYNTNNMQRLFWDNTSVTFGLS 173
                 ..:::.::...:..::.::..:.|..|:|....:....|    |:.....::.|.||  |
 Frog   586 -----RQKLIEKRLYRLVLEIAVHVVFLIMTMIMAYADKSPNEY----NLNIAVSNSFSSTF--S 639

  Fly   174 QVYFIYQVHSYMKITLVEAFYAQKTNGYEGWWAMEQWQKIGVVRLRQMRPVDCHIGLGKPEWDKK 238
            |:..|...:|:...||:...|:|    |.|:........:|..|:||:|.......:|    |..
 Frog   640 QIGNIEDFYSWTSSTLLPNLYSQ----YTGFITDGNCFLLGSPRIRQLRRAQSQYSIG----DTG 696

  Fly   239 TYAPEWRLPYHRMHYTEKFWRIYDPFVPAEFEPSFLNGLLLNYDHYGYLLNYPEVAGYVVLMMST 303
            .|..|| ||..|....:|.|:.|     .|.|       |:.|..:|. |.:....|:|..:.:.
 Frog   697 HYKAEW-LPLGRNDTPDKEWKYY-----TEKE-------LVGYPIWGQ-LGWYSGGGFVAELGNN 747

  Fly   304 KINCLKQIEYLRDYSWLDKNTSALFIDLTMYNADANLFTLITLRVENSPFGIQLPRVHVDSVSML 368
            .||....:.:|:...|||..|.|:|::..:|||:.|||.|.|..:|.|..|..|..|.:....:.
 Frog   748 IINASSILMWLQTNQWLDTYTKAVFVEFNVYNANVNLFCLATFIMETSAIGNFLTSVDLQIRKLS 812

  Fly   369 GNVETRSNSELL--ILFVYTVLVILFARGVFTKIWHHPAAAHEAWT-------MVDLAIYILNVF 424
            .:.....:|:.:  |:|:..||..:..:|:..|        .:.|:       ::||:|.::::.
 Frog   813 WSTTDIFSSQFISYIIFLIIVLYNIIQQGLLIK--------KQKWSYLTNIKNLLDLSIIMISIC 869

  Fly   425 LTVLAI------MRDI-----ETDALLQIIETATKGQYLDFQRPLRLHQMLFIVKGFLVCITTLR 478
            .|.|.|      .|||     :....:...|||. |:        .:|....   .|||.:.|.:
 Frog   870 NTGLYIKLALLCQRDINRYQQDRTRFVSFYETAI-GE--------SIHGYSI---AFLVSLMTAK 922

  Fly   479 LWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIGITLAVPNGNNAVVFSHMVQSVVTCM 543
            ||.:|...........||..||..:....:.|:::::|..||..|..|.....:.....:.||..
 Frog   923 LWSLLSLNPNLHLIMVTLRKAWDEIIYFLIAIIIIIVAYSITCNVLYGWKIYSYRTFFDTAVTIF 987

  Fly   544 WYSMG-FNG----DIHPADFFHGGRILGILLYLALVFLLAIILMNVFASVIYDYFNETSRILKEH 603
            ...:| ||.    |:.|        ::|.||....|..|..:|:|:|.|.|...|::..:....|
 Frog   988 SLLIGIFNYDQVLDLSP--------VIGSLLITTYVIFLVFVLVNIFLSAILAVFSKERQCPTPH 1044

  Fly   604 SNRSSITFLEFLHVEYADLF 623
            .::..:   :.|.::.:.||
 Frog  1045 KDKDVV---DLLMLKLSGLF 1061

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv2	NP_648970.2	PKD_channel	169..596	CDD:285288	115/451 (25%)
pkd1l3	XP_017949004.2	PLAT	66..183	CDD:412108
		PKD_channel	638..1035	CDD:400395	113/448 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276906at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010