Protein Alignment Afg3l2 and RPT3

DIOPT Version :10

• Sequence 1: NP_730248.2
• Gene: Afg3l2 / 39922
• FlyBaseID: FBgn0036702
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_010682.3
• Gene: RPT3 / 852003
• SGDID: S000002802
• Length: 428
• Species: Saccharomyces cerevisiae
• Alignment Length: 422
• Identity: 137/422 - (32%)
• Similarity: 201/422 - (47%)
• Gaps: 64/422 - (15%)

  Fly   186 KEISWKEFVNSYLS-----KGVVE--------------KLEVVNKKWVRVRLQQNSNSGSGVLWF 231
            |.:..|..|.||.|     .|.|.              ||:.:.|::..:.||::         :
Yeast    12 KAVEEKPAVKSYASLLAQLNGTVNNNSALSNVNSDIYFKLKKLEKEYELLTLQED---------Y 67

  Fly   232 NIGSVDSFERNLEAAQTEQGTESINFVPVIYRNEVE--------AASLTGLLPTLLIIGFLVYMM 288
            ........:|.|:.||.|  .:.|..||::....:|        .:|.||:...:.|:..|...:
Yeast    68 IKDEQRHLKRELKRAQEE--VKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDREL 130

  Fly   289 RKSADMMGGGRGRKGGGLFGGV---MQSTAKLTNPNE-IGVGFKDVAGCEEAKIEIMEFVNF-LK 348
            .|.:  |.....|....|...:   ..|:..:...|| ..|.:.||.|.:..|.||.|.|.. |.
Yeast   131 LKPS--MSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEIREAVELPLV 193

  Fly   349 NPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPSRVRDMF 413
            ....|..:|...|:|.:|.||||||||:|.||.|......||.|:||||:..::|.||..|||:|
Yeast   194 QADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVF 258

  Fly   414 AMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRVDI 478
            .:||::||.|:||||:|::..||.....|...|.:..|.:||.:||||:.:|||.|:.||||.|.
Yeast   259 RLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADT 323

  Fly   479 LDKALMRPGRFDRQIYVPA-PDIKGRASIF-----KVHL---GNLKTSLDKNELSRKMAALTPGF 534
            ||.||:||||.||:|..|: .|.:.|..||     |:.|   .:|.:.:.:|:          ..
Yeast   324 LDPALLRPGRLDRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRND----------SL 378

  Fly   535 TGADIANVCNEAALIAARDSKDSIVLKHFEQA 566
            :||.||.:..||.|.|.|.::..|:....|:|
Yeast   379 SGAVIAAIMQEAGLRAVRKNRYVILQSDLEEA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Afg3l2	NP_730248.2	HflB	168..765	CDD:440233	137/422 (32%)
RPT3	NP_010682.3	PTZ00454	46..428	CDD:240423	129/388 (33%)