Protein Alignment Afg3l2 and RPT2

DIOPT Version :10

• Sequence 1: NP_730248.2
• Gene: Afg3l2 / 39922
• FlyBaseID: FBgn0036702
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_010277.1
• Gene: RPT2 / 851557
• SGDID: S000002165
• Length: 437
• Species: Saccharomyces cerevisiae
• Alignment Length: 505
• Identity: 154/505 - (30%)
• Similarity: 233/505 - (46%)
• Gaps: 95/505 - (18%)

  Fly    78 GKSSGQPKGSVGDKKPPAGSSKSASEKPSTSTPASVKPSRSQTDAKSDWNFGMFSNSSRGPAGKG 142
            |.||||      |||...||    ::||....|...|                |....|    ||
Yeast     4 GVSSGQ------DKKKKKGS----NQKPKYEPPVQSK----------------FGRKKR----KG 38

  Fly   143 GNSLGGR-PLGENGGGGDRERWILLGAIGAVVLVGSFAFFEMGYKEISWKEFV-NSYLSKGVVEK 205
            |.:...: |   |.....|.:..||    .:..:......|        :||| ||.:.|...:|
Yeast    39 GPATAEKLP---NIYPSTRCKLKLL----RMERIKDHLLLE--------EEFVSNSEILKPFEKK 88

  Fly   206 LEVVNKKWVRVRLQQNSNSGSGVLWFNIGSVDSFERNLEAAQTEQGTESINFVPVIYRNEVEAAS 270
            .|...|:...:|       |:.:   :||:::      |....:....:...:|..|     .:.
Yeast    89 QEEEKKQLEEIR-------GNPL---SIGTLE------EIIDDDHAIVTSPTMPDYY-----VSI 132

  Fly   271 LTGLLPTLLIIGFLVYMMRKSADMMGGGRGRKGGGLFGGVMQ-------STAKL-TNPNEIGVGF 327
            |:.:...||..|..|.:..|:..::             ||:|       |..|: .:|.|   .:
Yeast   133 LSFVDKELLEPGCSVLLHHKTMSIV-------------GVLQDDADPMVSVMKMDKSPTE---SY 181

  Fly   328 KDVAGCEEAKIEIMEFVNF-LKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFIT 391
            .|:.|.|....||.|.|.. |.:|:.|.::|.|.|||.:|.|.|||||||||||.|.:.:..|:.
Yeast   182 SDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLR 246

  Fly   392 VSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLNQLLV 456
            :.|||.::.::|.||...|.:|.:|.::||.|:|||||||:|.||.....||..|.:.|:.:||.
Yeast   247 IVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLN 311

  Fly   457 EMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKTSLDKN 521
            ::|||:...:|.|:.|||:::.||.||:||||.||:|....||:..:..|..:|...:..|.|.|
Yeast   312 QLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVN 376

  Fly   522 ELSRKMAALTPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERVI 571
              ...:.......:||||..:|.||.|:|.|:.:..:..:.|:||.|||:
Yeast   377 --LETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVM 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Afg3l2	NP_730248.2	HflB	168..765	CDD:440233	130/414 (31%)
RPT2	NP_010277.1	PTZ00361	1..437	CDD:185575	154/505 (30%)