DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6512 and ftsh9

DIOPT Version :9

Sequence 1:	NP_730248.2	Gene:	CG6512 / 39922	FlyBaseID:	FBgn0036702	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_568892.1	Gene:	ftsh9 / 836004	AraportID:	AT5G58870	Length:	806	Species:	Arabidopsis thaliana

Alignment Length:	799	Identity:	293/799 - (36%)
Similarity:	407/799 - (50%)	Gaps:	143/799 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 SEKPSTSTPASVKPSRSQTDAKSDWNFGMFSNSSRGPAGKGGNSLGGRPLGEN---GGGGDRERW 163
            |.|.|||:..:: .:..:.|.|        ::||.| .|| .|...||..|:|   ...|.:.:|
plant    77 SRKKSTSSSRTI-VNCQEGDQK--------ASSSEG-EGK-TNKDKGRKQGKNELWWSKGKKWQW 130

  Fly   164 ----------ILLGAIGAVVLV-----------GSFAFFEMGYKEISWKEFVNSYLSKGVVEKLE 207
                      ::|..:|.|:.|           ||....:..:..:.:.:|: |.::...|:|:|
plant   131 KPIIQAQEIGVMLLQLGIVMFVVRLLRPGIPLPGSEPRTQTTFMSVPYSDFL-SKVNNDEVQKVE 194

  Fly   208 VVNKKWVRVRLQQNSNSGSGVLWFNI---GSVDSFERNLEAAQTEQGTESI--NFVP---VIY-- 262
            |               .|..|| |.:   |::...|.:..:.:..:.:|::  :..|   |:|
plant   195 V---------------DGFHVL-FKLKDDGNLQESETSSSSIKLSESSETMLRSVAPTKRVVYST 243

  Fly   263 --------------RNEVEAAS---------LTGLLPTLLIIGFLVYMMRK-----SADMMGGGR 299
                          .|.||..|         .:||: .|..|..|..::.:     |....|..|
plant   244 TRPRDIKTPYEKMLENNVEFGSPDKRSGGFFNSGLI-VLFYIAVLAGLLHRFPVNFSQSTTGQLR 307

  Fly   300 GRKGGGLFGGVMQSTAKLTNPNEIGVGFKDVAGCEEAKIEIMEFVNFLKNPQQYIDLGAKIPKGA 364
            .||.||..||      |::...|. :.|.||||.:|||.|:.|.|.|||||.:|:.|||:.|:|.
plant   308 TRKSGGPGGG------KVSGDGET-ITFADVAGVDEAKEELEEIVEFLKNPDRYVRLGARPPRGV 365

  Fly   365 MLTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEI 429
            :|.|.|||||||||||.|||::||||:.|.|||:|::||:|.|||||:||.|:|.||.|:|||||
plant   366 LLVGLPGTGKTLLAKAVAGESDVPFISCSASEFVELYVGMGASRVRDLFARAKKEAPSIIFIDEI 430

  Fly   430 DAVGRKRGGK-TFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQI 493
            |||.:.|.|| ....:.|:|.||||||.|||||::::.|:||.||||.|:||.||.|||||||.:
plant   431 DAVAKSRDGKFRMVSNDEREQTLNQLLTEMDGFDSSSAVIVLGATNRADVLDPALRRPGRFDRVV 495

  Fly   494 YVPAPDIKGRASIFKVHLGNLKTSLDKNELSRKMAALTPGFTGADIANVCNEAALIAARDSKDSI 558
            .|.:||..||.||.|||:...:..|..:.....:|::|.||||||:||:.|||||:|.|.||.::
plant   496 TVESPDKVGRESILKVHVSKKELPLGDDVNLASIASMTTGFTGADLANLVNEAALLAGRKSKMTV 560

  Fly   559 VLKHFEQAIERVIAGMEKKTNVLAPEEKRTVAHHEAGHAVAGW----FLEHADPLLKVSIIPR-G 618
            ....|..|:||.|||:||||..|...||..||.|||||||.|.    .|.....:.|:||:|| |
plant   561 DKIDFIHAVERSIAGIEKKTARLKGSEKAVVARHEAGHAVVGTAVASLLSGQSRVEKLSILPRSG 625

  Fly   619 KGLGYAQYLP---KDHYLLSKEQLFDRMCMTLGGRVAEELFFN-RITTGAQDDLKKITDIAYSQV 679
            ..||:. |:|   :|.|||..::|..|:...||||.|||:.:: ||:|||.||:::.||:||..|
plant   626 GALGFT-YIPPTHEDRYLLFIDELHGRLVTLLGGRAAEEVVYSGRISTGALDDIRRATDMAYKAV 689

  Fly   680 VRFGMNEKVGQVSFDVGQAG--DPVFSKPYSEDTAQLIDNEVRSIIKCAHEATTSLLTKHKENVQ 742
            ..:|:|||:|.||.....||  |.....|:..|...|:|...|.:......|....||..:.|
plant   690 AEYGLNEKIGPVSVATLSAGGIDDSGGSPWGRDQGHLVDLVQREVTNLLQSALDVALTVVRAN-- 752

  Fly   743 KVAERLLQNEVLSRDDMIELLGPRPFKEKSTYEEFVEGTGSFEEDTTLPEGLKSWNKEKERTEPL 807
                          .|::|.||     .:...||.|||           |.|:.|......:|.|
plant   753 --------------PDVLEGLG-----AQLEDEEKVEG-----------EELQKWLNRVVPSEEL 787

  Fly   808 DAGSTPSSPPTKPVTAQSS 826
            ............|..|.||
plant   788 AVFIKGKQTALLPAQASSS 806

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6512	NP_730248.2	FtsH_ext	163..259	CDD:284011	20/121 (17%)
		FtsH_fam	271..764	CDD:273520	232/509 (46%)
		AAA	365..496	CDD:278434	83/131 (63%)
		Peptidase_M41	580..762	CDD:279742	69/192 (36%)
ftsh9	NP_568892.1	FtsH_fam	322..759	CDD:273520	217/454 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217929at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820