DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6512 and FTSH11

DIOPT Version :9

Sequence 1:	NP_730248.2	Gene:	CG6512 / 39922	FlyBaseID:	FBgn0036702	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_568787.1	Gene:	FTSH11 / 835398	AraportID:	AT5G53170	Length:	806	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	227/526 - (43%)
Similarity:	318/526 - (60%)	Gaps:	44/526 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 LLPTLLI---IGFLVYMMRKSA--DMMG--GGRGRKGGGLFGGVMQSTAKLTNPNEIG------- 324
            |:.|:|.   :| ||::|..:|  ..:|  ||.|..|.|        ::...:|.|:.
plant   301 LVSTILFTVAVG-LVWIMGAAALQKYIGSLGGIGTSGVG--------SSSSYSPKELNKEITPEK 356

  Fly   325 --VGFKDVAGCEEAKIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANV 387
              ..||||.||::||.|:.|.|.:||||.::..||.|:|||.:|||.|||||||||||.||||.|
plant   357 NVKTFKDVKGCDDAKQELEEVVEYLKNPSKFTRLGGKLPKGILLTGAPGTGKTLLAKAIAGEAGV 421

  Fly   388 PFITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLN 452
            ||...:||||.|||||||..|||.:|..|:|.||||:|||||||||..|  |.:.||:::  ||:
plant   422 PFFYRAGSEFEEMFVGVGARRVRSLFQAAKKKAPCIIFIDEIDAVGSTR--KQWEGHTKK--TLH 482

  Fly   453 QLLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKTS 517
            |||||||||.....::|:||||..||||.||.|||||||.|.||:||::||..|.:::|.....|
plant   483 QLLVEMDGFEQNEGIIVMAATNLPDILDPALTRPGRFDRHIVVPSPDVRGREEILELYLQGKPMS 547

  Fly   518 LDKNELSRKMAALTPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERVIAGMEKKTNVLA 582
            .|.:  .:.:|..||||.|||:||:.|.||:.||.:..:.:..:..|.|.:|::.|.|:||..::
plant   548 EDVD--VKAIARGTPGFNGADLANLVNIAAIKAAVEGAEKLSSEQLEFAKDRIVMGTERKTMFVS 610

  Fly   583 PEEKRTVAHHEAGHAVAGWFLEHADPLLKVSIIPRGKGLGYAQYLP-KDHYLLSKEQLFDRMCMT 646
            .:.|:..|:||:|||:.....:.|.|:.|.:|:|||..||....|| .|...:||.||..|:.:.
plant   611 EDSKKLTAYHESGHAIVALNTKGAHPIHKATIMPRGSALGMVTQLPSNDETSVSKRQLLARLDVC 675

  Fly   647 LGGRVAEELFF--NRITTGAQDDLKKITDIAYSQVVRFGMNEKVGQVSFDVGQAGDPVFSKPYSE 709
            :||||||||.|  :.|||||..||.:.|::|...|...||:|.:|.|.         :..:| |.
plant   676 MGGRVAEELIFGLDHITTGASSDLSQATELAQYMVSSCGMSEAIGPVH---------IKERP-SS 730

  Fly   710 DTAQLIDNEVRSIIKCAHEATTSLLTKHKENVQKVAERLLQNEVLSRDDMIELLGPRPFKEKSTY 774
            |....||.||..:::.|:|...|||.:|::.:..:|..||:.|.|:.:|:..:|.|:...||...
plant   731 DMQSRIDAEVVKLLREAYERVKSLLKRHEKQLHTLANALLEYETLTAEDIKRILLPKQEGEKFEE 795

  Fly   775 EEFVEG 780
            ::..||
plant   796 QQQEEG 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6512	NP_730248.2	FtsH_ext	163..259	CDD:284011
		FtsH_fam	271..764	CDD:273520	221/508 (44%)
		AAA	365..496	CDD:278434	85/130 (65%)
		Peptidase_M41	580..762	CDD:279742	67/184 (36%)
FTSH11	NP_568787.1	FtsH_fam	355..784	CDD:273520	205/444 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217929at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820