DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6512 and ftsh7

DIOPT Version :9

Sequence 1:	NP_730248.2	Gene:	CG6512 / 39922	FlyBaseID:	FBgn0036702	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_566889.1	Gene:	ftsh7 / 823859	AraportID:	AT3G47060	Length:	802	Species:	Arabidopsis thaliana

Alignment Length:	802	Identity:	286/802 - (35%)
Similarity:	422/802 - (52%)	Gaps:	114/802 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 RYVVKQIQLLCKKPP----KGFEKYFEAGGKSSGQPKGSVGDKKPPAGSSKSASEKPSTSTPASV 113
            |:|...|.|..:|..    :..|::....|.|..:.:..|..::.....|.|..|:.|.||||..
plant    46 RFVSNSITLPLQKKQVTVLRNHERFNLWDGFSRKKSRLVVNCQEDDQNESSSEEEESSQSTPAKS 110

  Fly   114 KPSRSQTDAKSDWNFGMFSNSSRGPAGKGGNSLGGRPLGENGGGGDRERWILLGAIGAVVLV--- 175
            :..|.:.:.|..|:              .|.....:|:.:..|.|     :||..:..|:.|
plant   111 ERKREKKEDKVWWS--------------KGKKWQWQPIIQAQGIG-----VLLLQLSVVMFVMRL 156

  Fly   176 --------GSFAFFEMGYKEISWKEFVNSYLSKGVVEKLEVVNKKWVRVRLQQNSNSGSGVLWFN 232
                    ||....:..:..:.:.||: |.::...|:|:||               .|..|| |.
plant   157 LRPGIPLPGSEPRIQTTFVSVPYSEFL-SKVNSNQVQKVEV---------------DGVQVL-FK 204

  Fly   233 IGSVDSFERNLEAAQTEQGTESI--NFVP---VIYR----------------NEVEAAS------ 270
            :.....::.: |.::..|.:||:  ...|   |:|.                |.||..|
plant   205 LRDDGKWQES-ETSRLSQSSESLLRTVAPTKRVVYSTTRPGDIKTPYEKMLGNNVEFGSPEKRSG 268

  Fly   271 ------LTGLLPTLLIIGFLVYMMRKSADMMGGGRGRKGGGLFGGVMQSTAKLTNPNEIGVGFKD 329
                  |..|....::.|.:.:.:..|....|..|.||.||..||      |::...|. :.|.|
plant   269 GFFNSALIALFYIAVLAGLIRFPVSFSTSSTGQLRTRKAGGPDGG------KVSGGGET-ITFAD 326

  Fly   330 VAGCEEAKIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVSG 394
            |||.:|||.|:.|.|.||:||::|:.|||:.|:|.:|.|.|||||||||||.||||.||||:.|.
plant   327 VAGVDEAKEELEEIVEFLRNPEKYVRLGARPPRGVLLVGLPGTGKTLLAKAVAGEAEVPFISCSA 391

  Fly   395 SEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGK-TFGGHSEQENTLNQLLVEM 458
            |||:|::||:|.|||||:||.|:|.||.|:||||||||.:.|.|| ..|.:.|:|.||||||.||
plant   392 SEFVELYVGMGASRVRDLFARAKKEAPSIIFIDEIDAVAKSRDGKFRMGSNDEREQTLNQLLTEM 456

  Fly   459 DGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKTSLDKNEL 523
            |||::.:.|:||.||||.|:||.||.|||||||.:.|..||..||.||.:||:...:..|..:..
plant   457 DGFDSNSAVIVLGATNRADVLDPALRRPGRFDRVVTVETPDKIGRESILRVHVSKKELPLGDDVN 521

  Fly   524 SRKMAALTPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERVIAGMEKKTNVLAPEEKRT 588
            ...:|::|.||||||:||:.|||||:|.|.:|.::....|.||:||.|||:|||:..|...||..
plant   522 LGSIASMTTGFTGADLANLVNEAALLAGRKNKTNVEKIDFIQAVERSIAGIEKKSARLKGNEKAV 586

  Fly   589 VAHHEAGHAVAGWFLEH---ADPLL-KVSIIPR-GKGLGYAQYLP---KDHYLLSKEQLFDRMCM 645
            ||.|||||||.|..:.:   ..|.: |:||:|| |..||:. |:|   :|.|||..::|..|:..
plant   587 VARHEAGHAVVGTAVANLLTGQPRVEKLSILPRTGGALGFT-YIPPTSEDRYLLFIDELLGRLVT 650

  Fly   646 TLGGRVAEELFFN-RITTGAQDDLKKITDIAYSQVVRFGMNEKVGQVSFDVGQAG--DPVFSKPY 707
            .||||.|||:.:: ||:|||.||:::.||:||..|..:|:|:|:|.||......|  |.....|:
plant   651 LLGGRAAEEVVYSGRISTGAFDDIRRATDMAYKAVAEYGLNQKIGPVSVATLSGGGIDDSGGSPW 715

  Fly   708 SEDTAQLID---NEVRSIIKCAHEATTSLLTKHKENVQKVAERLLQNEVLSRDDMIELLGPRPFK 769
            ..|..:|:|   .||..:::.|.:...|::..:.:.::.:..:|.:.|.:..:::.:.|......
plant   716 GRDQGKLVDLVQKEVTILLQSALDVALSVVRANPDVLEGLGAQLEEKEKVEGEELQKWLSMVVAP 780

  Fly   770 EKSTYEEFVEGTGSFEEDTTLP 791
            |:...  ||||    :::..||
plant   781 EELAV--FVEG----KQELLLP 796

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6512	NP_730248.2	FtsH_ext	163..259	CDD:284011	21/108 (19%)
		FtsH_fam	271..764	CDD:273520	226/507 (45%)
		AAA	365..496	CDD:278434	85/131 (65%)
		Peptidase_M41	580..762	CDD:279742	67/195 (34%)
ftsh7	NP_566889.1	FtsH_ext	143..264	CDD:284011	28/138 (20%)
		FtsH_fam	270..755	CDD:273520	224/492 (46%)
		AAA	361..494	CDD:278434	85/132 (64%)
		Peptidase_M41	583..755	CDD:279742	64/172 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217929at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820