Protein Alignment Afg3l2 and VAR2

DIOPT Version :10

• Sequence 1: NP_730248.2
• Gene: Afg3l2 / 39922
• FlyBaseID: FBgn0036702
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_001323509.1
• Gene: VAR2 / 817646
• AraportID: AT2G30950
• Length: 699
• Species: Arabidopsis thaliana
• Alignment Length: 686
• Identity: 285/686 - (41%)
• Similarity: 384/686 - (55%)
• Gaps: 90/686 - (13%)

  Fly   164 ILLGAIG-AVVLVGSFAFFEMGY--KEISWKEFVNSYLSKGVVEKLEV---------------VN 210
            ||||..| .:|..|.....|.|.  ..:|:..|: .||.|..|.|:::               :.
plant    69 ILLGNAGVGLVASGKANADEQGVSSSRMSYSRFL-EYLDKDRVNKVDLYENGTIAIVEAVSPELG 132

  Fly   211 KKWVRVRLQQNSNSGSGVLWFNIGSVDSFERNLEAAQTEQGTESINFVPVIYRNEVEAASLTGLL 275
            .:..|||:|....|...:......::|....|   ||.:||:...|.:..:            ..
plant   133 NRVERVRVQLPGLSQELLQKLRAKNIDFAAHN---AQEDQGSVLFNLIGNL------------AF 182

  Fly   276 PTLLIIGFLVYMMRKSADMMGGGRGRKGGG----LFGGVMQSTAKLTNPNEIGVGFKDVAGCEEA 336
            |.|| ||.|..:.|:|    |||.|..||.    .||   ||.||.......||.|.||||.:||
plant   183 PALL-IGGLFLLSRRS----GGGMGGPGGPGNPLQFG---QSKAKFQMEPNTGVTFDDVAGVDEA 239

  Fly   337 KIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMF 401
            |.:.||.|.|||.|:::..:|||||||.:|.|||||||||||||.||||.|||.::|||||:|||
plant   240 KQDFMEVVEFLKKPERFTAVGAKIPKGVLLIGPPGTGKTLLAKAIAGEAGVPFFSISGSEFVEMF 304

  Fly   402 VGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLNQLLVEMDGFNTTTN 466
            ||||.|||||:|..|:::||||:|:||||||||:||....||:.|:|.||||||.|||||...|.
plant   305 VGVGASRVRDLFKKAKENAPCIVFVDEIDAVGRQRGTGIGGGNDEREQTLNQLLTEMDGFEGNTG 369

  Fly   467 VVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKTSLDKNELSRKMAAL- 530
            |:|:|||||.||||.||:||||||||:.|..||:|||..|.|||.||.|..   |::|.::.|:
plant   370 VIVVAATNRADILDSALLRPGRFDRQVSVDVPDVKGRTDILKVHAGNKKFD---NDVSLEIIAMR 431

  Fly   531 TPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERVIAGMEKKTNVLAPEEKRTVAHHEAG 595
            ||||:|||:||:.||||::|.|.::.||..|..:.:|:|::|||| .|.:...:.|..||:||.|
plant   432 TPGFSGADLANLLNEAAILAGRRARTSISSKEIDDSIDRIVAGME-GTVMTDGKSKSLVAYHEVG 495

  Fly   596 HAVAGWFLEHADPLLKVSIIPRGKGLGYAQYLPKDH-YLLSKEQLFDRMCMTLGGRVAEELFF-- 657
            |||.|......|.:.||::||||:..|...::|.|. .|:||:|||.|:...||||.|||:.|
plant   496 HAVCGTLTPGHDAVQKVTLIPRGQARGLTWFIPSDDPTLISKQQLFARIVGGLGGRAAEEIIFGD 560

  Fly   658 NRITTGAQDDLKKITDIAYSQVVRFGMNEKVGQVSFDVGQAGDPVFSK-----PYSEDTAQLIDN 717
            :.:||||..||::||.:|...|..|||:: :|..|.....|...|..:     ..||..|:.||:
plant   561 SEVTTGAVGDLQQITGLARQMVTTFGMSD-IGPWSLMDSSAQSDVIMRMMARNSMSEKLAEDIDS 624

  Fly   718 EVRSIIKCAHEATTSLLTKHKENVQKVAERLLQNEVLSRDDMIELLGPRPFKEKSTYEEFVEGTG 782
            .|:.:...|:|...|.:..::|.:.|:.|.||:.|.:..|:...:|           .||.|
plant   625 AVKKLSDSAYEIALSHIKNNREAMDKLVEVLLEKETIGGDEFRAIL-----------SEFTE--- 675

  Fly   783 SFEEDTTLPEGLKSWNKEKERTEPLDAGSTPSSPPT 818
                   :|         .|...|....:||:|.||
plant   676 -------IP---------PENRVPSSTTTTPASAPT 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Afg3l2	NP_730248.2	HflB	168..765	CDD:440233	270/627 (43%)
VAR2	NP_001323509.1	ftsH	89..680	CDD:214386	270/649 (42%)