Protein Alignment Afg3l2 and yme1l1a

DIOPT Version :10

• Sequence 1: NP_730248.2
• Gene: Afg3l2 / 39922
• FlyBaseID: FBgn0036702
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_005162918.2
• Gene: yme1l1a / 793098
• ZFINID: ZDB-GENE-091113-41
• Length: 729
• Species: Danio rerio
• Alignment Length: 606
• Identity: 220/606 - (36%)
• Similarity: 343/606 - (56%)
• Gaps: 67/606 - (11%)

  Fly   184 GYKEISWKEFVNS-------------YLSKGVVEKLEVVNKKWVRVRLQQNSNSGSGVLWFNIGS 235
            |:|.:|....:.|             ...||::.| |..:...:...|:||:...|....|..|.
Zfish   157 GFKTMSKSRHLRSSSEGPVEADNYTPVFMKGLIMK-EKTDTGSLEQLLKQNNLPESHQDAFKTGF 220

  Fly   236 VDSFERNLEAAQTEQGTESINFVPVIYRNEVEAASLTGLLPTLLIIGFLVYMMRKSADMMGGG-- 298
            .:.|.:  ..|.|::..:|:....:|             :..||:.|  :|.:.:|....|.|
Zfish   221 TEGFMK--AQALTKRTQDSVKRTRLI-------------IFVLLLAG--IYGVSRSPFFSGKGSF 268

  Fly   299 ----RGRKGGGLFGGVMQSTAKLTNPNEI-GVGFKDVAGCEEAKIEIMEFVNFLKNPQQYIDLGA 358
                |.|...||...|        :|.:: .:.|:.|.|.||||.|:.:.|.||:|||::..||.
Zfish   269 SDTVRFRTTSGLDSSV--------DPVQMKNITFEHVKGVEEAKNELQDVVEFLRNPQKFTVLGG 325

  Fly   359 KIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCI 423
            |:|||.:|.|||||||||||:|.||||:|||...|||||.|||||||.||:|::|..|:..|||:
Zfish   326 KLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFKEAKASAPCV 390

  Fly   424 LFIDEIDAVGRKRGGKTFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGR 488
            :||||:|:||.||.......:|.|  |:||||.|||||.....|:|:.|||..:.||.||:||||
Zfish   391 IFIDELDSVGGKRIESPMHPYSRQ--TINQLLAEMDGFKPNEGVIVIGATNFAEALDNALVRPGR 453

  Fly   489 FDRQIYVPAPDIKGRASIFKVHLGNLK--TSLDKNELSRKMAALTPGFTGADIANVCNEAALIAA 551
            ||.|:.||.||:|||..|.:.:|..:|  :::|...::|.    |.||:||::.|:.|:|||.||
Zfish   454 FDMQVTVPIPDVKGRTEILEWYLKKIKVDSAIDAEIIARG----TVGFSGAELENLVNQAALKAA 514

  Fly   552 RDSKDSIVLKHFEQAIERVIAGMEKKTNVLAPEEKRTVAHHEAGHAVAGWFLEHADPLLKVSIIP 616
            .|.||.:.:|..|.|.::::.|.|:::..:....|...|:||:|||:..::.:.|.|:.|.:|:|
Zfish   515 ADGKDLVTMKELEFAKDKILMGPERRSVEIDKRNKTITAYHESGHAIVAYYTKDAMPINKATIMP 579

  Fly   617 RGKGLGYAQYLPK-DHYLLSKEQLFDRMCMTLGGRVAEELFF--NRITTGAQDDLKKITDIAYSQ 678
            ||..||:...||: |.:..::.||..:|.:::||||||||.|  ::||:||..|....|.||...
Zfish   580 RGPSLGHVSLLPENDRWSETRAQLLAQMDVSMGGRVAEELVFGNDQITSGASSDFDGATKIAQMM 644

  Fly   679 VVRFGMNEKVGQVSF-DVGQAGDPVFSKPYSEDTAQLIDNEVRSIIKCAHEATTSLLTKHKENVQ 742
            |.||||::|:|.::: |:.:         :|.:|...::.|:|.:::.::|....:|..:.:..:
Zfish   645 VTRFGMSDKLGVMTYSDLTK---------HSPETRAAVEQEIRVLLQSSYERAKKILKTYSKEHK 700

  Fly   743 KVAERLLQNEVLSRDDMIELL 763
            .:|:.||..|.|:..::..:|
Zfish   701 LLADALLTYETLNAKEIQMIL 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Afg3l2	NP_730248.2	HflB	168..765	CDD:440233	220/606 (36%)
yme1l1a	XP_005162918.2	None