DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6512 and Bcs1l

DIOPT Version :9

Sequence 1:	NP_730248.2	Gene:	CG6512 / 39922	FlyBaseID:	FBgn0036702	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_001292581.1	Gene:	Bcs1l / 66821	MGIID:	1914071	Length:	418	Species:	Mus musculus

Alignment Length:	306	Identity:	75/306 - (24%)
Similarity:	125/306 - (40%)	Gaps:	85/306 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 KWVRVRLQQNSNSGSGVLWFNIGSVDSFERNLEAAQTEQGT--ESINFVPV-----IYRNEVEAA 269
            ||:||  ::|                   |:::....:.||  ||:.|..:     ::.|.:|.|
Mouse   111 KWIRV--ERN-------------------RDMQMVDLQTGTPWESVTFTALGTDRKVFFNILEEA 154

  Fly   270 SLTGLLPTLLIIGFLVYMMRKSADMMGGGRGRKGGGLFGGVMQSTAKLTNPNEIGVGFKDVAGCE 334
            ....|...   .|..|......::....|..|:...|...|:|.          |:..:.|.
Mouse   155 RALALQQE---EGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQ----------GLADRIVK--- 203

  Fly   335 EAKIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEA--NVPFITVSGSEF 397
                :|.||::   ||:.|||.|....:|.:|.||||.||:....|.|||.  ::..::::.|
Mouse   204 ----DIREFID---NPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDS-- 259

  Fly   398 LEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKR-------------GGKTFGGHSEQEN 449
                 .:...|:..:.::|.:.:  ::.::::||....|             |..||.|
Mouse   260 -----SLSDDRLNHLLSVAPQQS--LVLLEDVDAAFLSRDLAVENPIKYQGLGRLTFSG------ 311

  Fly   450 TLNQLLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYV 495
                ||..:||..:|...:|...||.:|.||.||:||||.|.:.||
Mouse   312 ----LLNALDGVASTEARIVFMTTNYIDRLDPALIRPGRVDLKEYV 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6512	NP_730248.2	FtsH_ext	163..259	CDD:284011	11/48 (23%)
		FtsH_fam	271..764	CDD:273520	61/240 (25%)
		AAA	365..496	CDD:278434	41/146 (28%)
		Peptidase_M41	580..762	CDD:279742
Bcs1l	NP_001292581.1	BCS1_N	24..191	CDD:214980	20/103 (19%)
		AAA	223..354	CDD:214640	42/150 (28%)
		AAA	226..355	CDD:278434	41/147 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900