Protein Alignment Afg3l2 and BCS1L

DIOPT Version :10

• Sequence 1: NP_730248.2
• Gene: Afg3l2 / 39922
• FlyBaseID: FBgn0036702
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_004319.1
• Gene: BCS1L / 617
• HGNCID: 1020
• Length: 419
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 80/335 - (23%)
• Similarity: 126/335 - (37%)
• Gaps: 98/335 - (29%)

  Fly   196 SYL---SKGVVEKLEVV----------NKKWVRVRLQQNSNSGSGVLWFNIGSVDSFERNLEAAQ 247
            |||   |..:..|.|.|          ..||:||..                     .|.::...
Human    82 SYLQHESGRISTKFEFVPSPGNHFIWYRGKWIRVER---------------------SREMQMID 125

  Fly   248 TEQGT--ESINFVPV-----IYRNEVEAASLTGLLPTLLIIGFLVYMMRKSADMMGGGRGRKGGG 305
            .:.||  ||:.|..:     ::.|.:|.|....|...   .|..|......::....|..|:...
Human   126 LQTGTPWESVTFTALGTDRKVFFNILEEARELALQQE---EGKTVMYTAVGSEWRPFGYPRRRRP 187

  Fly   306 LFGGVMQSTAKLTNPNEIGVGFKDVAGCEEAKIEIMEFVNFLKNPQQYIDLGAKIPKGAMLTGPP 370
            |...|:|.          |:..:.|...:|          |:.||:.|.|.|....:|.:|.|||
Human   188 LNSVVLQQ----------GLADRIVRDVQE----------FIDNPKWYTDRGIPYRRGYLLYGPP 232

  Fly   371 GTGKTLLAKATAGEA--NVPFITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVG 433
            |.||:....|.|||.  ::..::::.|       .:...|:..:.::|.:.:  ::.::::||..
Human   233 GCGKSSFITALAGELEHSICLLSLTDS-------SLSDDRLNHLLSVAPQQS--LVLLEDVDAAF 288

  Fly   434 RKR-------------GGKTFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRVDILDKALMR 485
            ..|             |..||.|          ||..:||..:|...:|...||.||.||.||:|
Human   289 LSRDLAVENPVKYQGLGRLTFSG----------LLNALDGVASTEARIVFMTTNHVDRLDPALIR 343

  Fly   486 PGRFDRQIYV 495
            |||.|.:.||
Human   344 PGRVDLKEYV 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Afg3l2	NP_730248.2	HflB	168..765	CDD:440233	80/335 (24%)
BCS1L	NP_004319.1	BCS1_N	24..191	CDD:214980	26/132 (20%)
		RecA-like_BCS1	201..353	CDD:410918	49/180 (27%)