Protein Alignment Afg3l2 and PSMC6

DIOPT Version :10

• Sequence 1: NP_730248.2
• Gene: Afg3l2 / 39922
• FlyBaseID: FBgn0036702
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_002797.4
• Gene: PSMC6 / 5706
• HGNCID: 9553
• Length: 389
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 99/249 - (39%)
• Similarity: 148/249 - (59%)
• Gaps: 7/249 - (2%)

  Fly   325 VGFKDVAGCEEAKIEIMEFVNF-LKNPQQYIDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVP 388
            |.:.::.|..|...|:.|.:.. |.||:.:..:|...|||.:|.|||||||||||:|.|.:.:..
Human   130 VSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCN 194

  Fly   389 FITVSGSEFLEMFVGVGPSRVRDMFAMARKHAPCILFIDEIDAVGRKRGGKTFGGHSEQENTLNQ 453
            |:.|..|..::.::|.....:|:||..||.|.|||:|:|||||:|.:|..:......|.:.||.:
Human   195 FLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLME 259

  Fly   454 LLVEMDGFNTTTNVVVLAATNRVDILDKALMRPGRFDRQIYVPAPDIKGRASIFKVHLGNLKT-- 516
            ||.:||||:|...|.::.||||.|.||.||:||||.||:|::..|:.:.|..|.|:|.|.:..
Human   260 LLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHG 324

  Fly   517 SLDKNELSRKMAALTPGFTGADIANVCNEAALIAARDSKDSIVLKHFEQAIERV 570
            .:|...:.:    |:.||.|||:.|||.||.:.|.|...|.:|.:.|.:|:.:|
Human   325 EIDYEAIVK----LSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKV 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Afg3l2	NP_730248.2	HflB	168..765	CDD:440233	99/249 (40%)
PSMC6	NP_002797.4	PRK03992	5..379	CDD:179699	99/249 (40%)