Protein Alignment Rbp6 and HNRNPDL

DIOPT Version :10

• Sequence 1: NP_001097631.1
• Gene: Rbp6 / 39919
• FlyBaseID: FBgn0260943
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_112740.1
• Gene: HNRNPDL / 9987
• HGNCID: 5037
• Length: 420
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 93/213 - (43%)
• Similarity: 117/213 - (54%)
• Gaps: 18/213 - (8%)

  Fly     4 KIEQQQQQQQVELGPCSPSEVPNDPGKMFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRR 68
            ||...:.||              |.||||||||||.||.:.|.:|..|:|::.:..:..||.|.|
Human   137 KINASKNQQ--------------DDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGR 187

  Fly    69 SRGFGFVTFSDPNSVDKVLTQGTHELDGKKVDPKVAFPRRAHPKMVTRTKKIFVGGLSAPTTLED 133
            |||||||.|.|..||||||....|:||||.:|||    |....|.....||:||||||..|:.|.
Human   188 SRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPK----RAKALKGKEPPKKVFVGGLSPDTSEEQ 248

  Fly   134 VKSYFEQFGPIEDAMLMFDKQTNRHRGFGFVTFQSEDVVDKVCEIHFHEINNKMVECKKAQPKEV 198
            :|.||..||.||:..|..|.:||..|||.|:|:..|:.|.|:.|..:|:|.:...|.|.||||||
Human   249 IKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEV 313

  Fly   199 MLPANLAKTRAAGRSAYG 216
            .......:....|.:|.|
Human   314 YRQQQQQQKGGRGAAAGG 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbp6	NP_001097631.1	RRM1_MSI	30..105	CDD:409990	42/74 (57%)
		RRM2_MSI	119..192	CDD:240769	32/72 (44%)
HNRNPDL	NP_112740.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..83
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..120
		RRM1_hnRPDL	149..224	CDD:410152	43/78 (55%)
		RRM2_hnRPDL	234..308	CDD:409998	33/73 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..348		4/19 (21%)
		Necessary for interaction with TNPO1. /evidence=ECO:0000269|PubMed:9524220	342..420
		Necessary for its nuclear import and export	396..420
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..420