Protein Alignment Rbp6 and SRSF6

DIOPT Version :10

• Sequence 1: NP_001097631.1
• Gene: Rbp6 / 39919
• FlyBaseID: FBgn0260943
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_006266.2
• Gene: SRSF6 / 6431
• HGNCID: 10788
• Length: 344
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 55/294 - (18%)
• Similarity: 112/294 - (38%)
• Gaps: 70/294 - (23%)

  Fly    30 KMFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRRSRGFGFVTFSDPNSVDKVLTQGTHEL 94
            :::||.||:....:.::.:|..||.:.|..:        ..|:|||.|.|....|    ...:||
Human     3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDL--------KNGYGFVEFEDSRDAD----DAVYEL 55

  Fly    95 DGKK------VDPKVAFPRR-------------------------AHPKMVTRTKKIFVGGLSAP 128
            :||:      :......|||                         .:...|....::.|..||:.
Human    56 NGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR 120

  Fly   129 TTLEDVKSYFEQFGPI--EDAMLMFDKQTNRHRGFGFVTFQS-EDVVDKVCEIHFHEINNKMVEC 190
            .:.:|:|.:..|.|.:  .||   ..::||.    |.:.|:| .|:...:.::...|||.:.:..
Human   121 CSWQDLKDFMRQAGEVTYADA---HKERTNE----GVIEFRSYSDMKRALDKLDGTEINGRNIRL 178

  Fly   191 KKAQPKEVMLPANLAKTRAAGRSAYGELVVWGSSHAHSTAATSAAAAGLLPSSLAAAASVLQQQQ 255
            .:.:|            |.:.|.:|.     ||.....:...|.:.:.....|.:.:.|..:.:.
Human   179 IEDKP------------RTSHRRSYS-----GSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRS 226

  Fly   256 QQQQQQQQQQQQQQQHHQQLHHTHPQSPAHSHAH 289
            :.:.:.:.:.:.:.:..:....:.|:|...||:|
Human   227 RSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSH 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbp6	NP_001097631.1	RRM1_MSI	30..105	CDD:409990	19/80 (24%)
		RRM2_MSI	119..192	CDD:240769	18/75 (24%)
SRSF6	NP_006266.2	RRM1_SRSF6	1..72	CDD:410009	19/80 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..103		1/27 (4%)
		RRM2_SRSF6	110..182	CDD:410159	18/78 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..344		14/102 (14%)