Protein Alignment Rbp6 and MSI1

DIOPT Version :9

• Sequence 1: NP_001097631.1
• Gene: Rbp6 / 39919
• FlyBaseID: FBgn0260943
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_002433.1
• Gene: MSI1 / 4440
• HGNCID: 7330
• Length: 362
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 185/424 - (43%)
• Similarity: 224/424 - (52%)
• Gaps: 96/424 - (22%)

  Fly    17 GPCSPSEVPNDPGKMFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRRSRGFGFVTFSDPN 81
            |..|| :.|:||.|||||||||||:.|.||:|||::|::.|.:||:||.|:||||||||||.|..
Human     9 GLASP-DSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQA 72

  Fly    82 SVDKVLTQGTHELDGKKVDPKVAFPRRAHPKMVTRTKKIFVGGLSAPTTLEDVKSYFEQFGPIED 146
            .|||||.|..||||.|.:||||||||||.||||||||||||||||..||:||||.||||||.::|
Human    73 GVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDD 137

  Fly   147 AMLMFDKQTNRHRGFGFVTFQSEDVVDKVCEIHFHEINNKMVECKKAQPKEVMLPANLAKTRAA- 210
            |||||||.||||||||||||:|||:|:||||||||||||||||||||||||||.|...|:.|:.
Human   138 AMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRV 202

  Fly   211 ---GRSAY----GELVVWGSSHAHSTAATSAAAAGLLPSSLAAAASVLQQQQQQQQQQQQQQQQQ 268
               |..|:    |.|   |.....:|...|.:..||.|.
Human   203 MPYGMDAFMLGIGML---GYPGFQATTYASRSYTGLAPG-------------------------- 238

  Fly   269 QQHHQQLHHTHPQSPAHSHAHHPHTHSHSQLLGSLRYTPY-PLPAHLSAAAVVVAQQQHHHQQQQ 332
             ..:|.......::|..|....|.       |.::..|.| |:.|..:|||||
Human   239 -YTYQFPEFRVERTPLPSAPVLPE-------LTAIPLTAYGPMAAAAAAAAVV------------ 283

  Fly   333 QQQQQQQQQQVVAAQQQHQQQQSLAQVVAAAAGAAPGLLPLANPAPPATPSLLQFAAGQSNAALA 397
                                         ...|:.|..:.   |.|.:|||......|.::....
Human   284 -----------------------------RGTGSHPWTMA---PPPGSTPSRTGGFLGTTSPGPM 316

  Fly   398 NSLYADAAAVVGYKRLLAAAAVSSGLRAPTTALG 431
            ..||..|....|....::||:     .||:|..|
Human   317 AELYGAANQDSGVSSYISAAS-----PAPSTGFG 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbp6	NP_001097631.1	RRM1_MSI	31..105	CDD:241020	49/73 (67%)
		RRM2_MSI	119..192	CDD:240769	61/72 (85%)
MSI1	NP_002433.1	RRM1_MSI	21..96	CDD:409990	50/74 (68%)
		PABP-1234	<32..339	CDD:130689	164/392 (42%)
		RRM2_MSI	110..183	CDD:240769	61/72 (85%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5529
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	359	1.000	Inparanoid score	I2219
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565323at2759
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	1	1.000	-	-		otm42259
orthoMCL	1	0.900	-	-		OOG6_101082
Panther	1	1.100	-	-	O	PTHR48032
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1869
SonicParanoid	1	1.000	-	-		X310
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860