Protein Alignment CG7724 and SDR42E1

DIOPT Version :10

• Sequence 1: NP_648957.1
• Gene: CG7724 / 39918
• FlyBaseID: FBgn0036698
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_660151.2
• Gene: SDR42E1 / 93517
• HGNCID: 29834
• Length: 393
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 90/331 - (27%)
• Similarity: 137/331 - (41%)
• Gaps: 55/331 - (16%)

  Fly     7 EVLLVTGGSGFLGQHLIKQLLERKEELGIKEIRSLDIVPYKNNIGHEETSLLRTYVADIGGDLKA 71
            |.:|:|||||:.|..|...|.:....:.:.:|.|             ....:...:..|.||::.
Human     9 ESVLITGGSGYFGFRLGCALNQNGVHVILFDISS-------------PAQTIPEGIKFIQGDIRH 60

  Fly    72 LSPI---FNGVD--GVFHCAA-SVKIEYPPNYEELERVNVNGTLAVVDLCIQNNVKRLVYTSCTS 130
            ||.:   |...|  .|||.|: .:......|...::.|||.||..::.:|.:..|.||||||..:
Human    61 LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFN 125

  Fly   131 VCFVPFKGRSTFSAVINSTESKTDTPTLDSSTLWEQDNQFLIPG-YASSKLRAENIVLNSNGAPL 194
            |.   |.|:    .:.|..||....|.            .|.|. |:.:|..||..||.:|..||
Human   126 VI---FGGQ----VIRNGDESLPYLPL------------HLHPDHYSRTKSIAEQKVLEANATPL 171

  Fly   195 HNQKEYLATSAMRAPLTYGECDSHFITEIFDFLSTRGWVF----PRIAGVGGKQQLVYAGNVAWG 255
            ......|.|.|:|....||..:...:..|..::....:.|    ||     ...:.|:..|:...
Human   172 DRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPR-----SLVEFVHVDNLVQA 231

  Fly   256 HICAYKALKVSDKA--VNGLPVFVTDDTGINDVSRFVQKMAVLGERFKVKTSWWYVPHFLFFFLA 318
            ||.|.:||: :||.  .:|.|.|::|...:|:...|...:..||..|....    :|..|.:..|
Human   232 HILASEALR-ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTR----LPLTLVYCFA 291

  Fly   319 FLLEVV 324
            ||.|:|
Human   292 FLTEMV 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7724	NP_648957.1	Rossmann-fold NAD(P)(+)-binding proteins	8..381	CDD:473865	89/330 (27%)
SDR42E1	NP_660151.2	3b-HSD_like_1_SDR_e	10..350	CDD:187672	89/330 (27%)