Protein Alignment CG7724 and HSD3B7

DIOPT Version :10

• Sequence 1: NP_648957.1
• Gene: CG7724 / 39918
• FlyBaseID: FBgn0036698
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_079469.2
• Gene: HSD3B7 / 80270
• HGNCID: 18324
• Length: 369
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 119/387 - (30%)
• Similarity: 174/387 - (44%)
• Gaps: 51/387 - (13%)

  Fly     8 VLLVTGGSGFLGQHLIKQLLERKEELGIKEIRSLD--IVPYKNNIGHEETSLLRTYVADIGGDLK 70
            |.|||||.||||:|:::.||:|:..||  |:|..|  :.|:...:   :|..:|  |..|.||:.
Human    11 VYLVTGGCGFLGEHVVRMLLQREPRLG--ELRVFDQHLGPWLEEL---KTGPVR--VTAIQGDVT 68

  Fly    71 ALSPIFNGVDG---VFHCAASVKIEYPPNYEELERVNVNGTLAVVDLCIQNNVKRLVYTSCTSVC 132
            ....:...|.|   |.|.|..|.:....:.:.:..|||.||..|::.|:|...:.|||||...|.
Human    69 QAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133

  Fly   133 FVPFKGRSTFSAVINSTESKTDTPTLDSSTLWEQDNQFLIPGYASSKLRAENIVLNSNGAPLHNQ 197
            ....||...:       ....|||       :|..::.   .|..||..||.:||.:||..:...
Human   134 GPNTKGHPFY-------RGNEDTP-------YEAVHRH---PYPCSKALAEWLVLEANGRKVRGG 181

  Fly   198 KEYLATSAMRAPLTYGECDSHFITEIFDF----LSTRGWVFPRI-AGVGGKQQLVYAGNVAWGHI 257
            .. |.|.|:|....|||  .|.|..  ||    |...||:|..| |.|  :...||.|||||.|:
Human   182 LP-LVTCALRPTGIYGE--GHQIMR--DFYRQGLRLGGWLFRAIPASV--EHGRVYVGNVAWMHV 239

  Fly   258 CAYKALKVSDKAVNGLPVFVTDDTGINDVSRFVQKMAVLGE-RFKVKTSWWYVPHFLFFFLA--- 318
            .|.:.|:.....:.|...|..|.:.......|  .|..||. ..::..:...:|::|..|||
Human   240 LAARELEQRATLMGGQVYFCYDGSPYRSYEDF--NMEFLGPCGLRLVGARPLLPYWLLVFLAALN 302

  Fly   319 FLLEVVVRVAYPYTKYRLRYSLRAIASYTSSMLMYNRLRASIHMDYMPLFDPDASAERSAKW 380
            .||:.::|....|......|:| |:|:.|.::   :..:|..|..|.|||..:.|..|:..|
Human   303 ALLQWLLRPLVLYAPLLNPYTL-AVANTTFTV---STDKAQRHFGYEPLFSWEDSRTRTILW 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7724	NP_648957.1	Rossmann-fold NAD(P)(+)-binding proteins	8..381	CDD:473865	119/387 (31%)
HSD3B7	NP_079469.2	3b-HSD_HSDB1_like_SDR_e	11..361	CDD:187671	119/387 (31%)