Protein Alignment CG7724 and Hsd3b3

DIOPT Version :10

• Sequence 1: NP_648957.1
• Gene: CG7724 / 39918
• FlyBaseID: FBgn0036698
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_001036084.1
• Gene: Hsd3b3 / 682974
• RGDID: 1592771
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 403
• Identity: 111/403 - (27%)
• Similarity: 185/403 - (45%)
• Gaps: 55/403 - (13%)

  Fly    10 LVTGGSGFLGQHLIKQLLERKEELGIKEIRSLDIV--PYKNNIGHEETSLLRT--YVADIGGDL- 69
            ||||..||:||.:|:.|::.||   ::|:|:||.|  |...    ||.|.|:|  .|..:.||:
  Rat     7 LVTGAGGFVGQRIIRMLVQEKE---LQEVRALDKVFRPETK----EEFSKLQTKAKVTMLEGDIL 64

  Fly    70 --KALSPIFNGVDGVFHCAASVKIEYPPNYEELERVNVNGTLAVVDLCIQNNVKRLVYTSCTSVC 132
              :.|.....|:..|.|.|:.:........:.:..||:.||..:::..|..:|...:|.|...|.
  Rat    65 DAQYLRRACQGISVVIHTASVMDFSRVLPRQTILDVNLKGTQNLLEAGIHASVPAFIYCSTVDVA 129

  Fly   133 FVPFKGRSTF-SAVINSTESKTDTPTLDSSTLWEQDNQFLIPGYASSKLRAENIVLNSNGAPLHN 196
                 |.::: ..::|..|.:....|      |...       |..||..||..||.:||:.|.|
  Rat   130 -----GPNSYKKTILNGREEEHHEST------WSNP-------YPYSKKMAEKAVLAANGSILKN 176

  Fly   197 QKEYLATSAMRAPLTYGECDSHFITEIFDFLSTRGWVFPRIAGVGGKQQL---VYAGNVAWGHIC 258
            ... |.|.|:|....|||........|...|..:|     :..|.||..:   ||.|||||.||.
  Rat   177 GGT-LHTCALRPMYIYGERGQFLSRIIIMALKNKG-----VLNVTGKFSIVNPVYVGNVAWAHIL 235

  Fly   259 AYKALKVSDKAVN--GLPVFVTDDT---GINDVSRFVQKMAVLGERFKVK-TSWWYVPHFLFFFL 317
            |.:.|:...|:.|  |...:::|||   ..:|::      ..|.:.:.:: .|.|.:|..|.::|
  Rat   236 AARGLRDPKKSQNIQGQFYYISDDTPHQSYDDLN------CTLSKEWGLRLDSSWSLPLPLLYWL 294

  Fly   318 AFLLEVVVRVAYPYTKYRLRYSLRAIASYTSSMLMYNRLRASIHMDYMPLFDPDASAERSAKWYA 382
            |||||.|..:..|:..||..::.. :.:.::|...::..:|...:.|.||...:.:.:::::|..
  Rat   295 AFLLETVSFLLRPFYNYRPPFNCH-LVTLSNSKFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIG 358

  Fly   383 TWWDQRQQAQKLK 395
            |..:|.::....|
  Rat   359 TLVEQHRETLDTK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7724	NP_648957.1	Rossmann-fold NAD(P)(+)-binding proteins	8..381	CDD:473865	107/387 (28%)
Hsd3b3	NP_001036084.1	Rossmann-fold NAD(P)(+)-binding proteins	5..357	CDD:473865	107/387 (28%)