Protein Alignment CG7724 and Hsd3b1

DIOPT Version :10

• Sequence 1: NP_648957.1
• Gene: CG7724 / 39918
• FlyBaseID: FBgn0036698
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_001007720.3
• Gene: Hsd3b1 / 360348
• RGDID: 1308676
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 403
• Identity: 114/403 - (28%)
• Similarity: 190/403 - (47%)
• Gaps: 55/403 - (13%)

  Fly    10 LVTGGSGFLGQHLIKQLLERKEELGIKEIRSLDIV--PYKNNIGHEETSLLRT--YVADIGGDL- 69
            ||||..||:||.:|:.|::.||   ::|:|:||.|  |...    ||.|.|:|  .|..:.||:
  Rat     7 LVTGAGGFVGQRIIRMLVQEKE---LQEVRALDKVFRPETK----EEFSKLQTKAKVTMLEGDIL 64

  Fly    70 --KALSPIFNGVDGVFHCAASVKIEYPPNYEELERVNVNGTLAVVDLCIQNNVKRLVYTSCTSVC 132
              :.|.....|:..|.|.||.:.:.:....:.:..||:.||..:::.|::.:|...:|.|...|.
  Rat    65 DAQYLRRACQGISVVIHTAAVIDVSHVLPRQTILDVNLKGTQNILEACVEASVPAFIYCSTVDVA 129

  Fly   133 FVPFKGRSTFSAVI-NSTESKTDTPTLDSSTLWEQDNQFLIPGYASSKLRAENIVLNSNGAPLHN 196
                 |.:::..:| |..|.:....|      |..       .|..||..||..||.:||:.|.|
  Rat   130 -----GPNSYKKIILNGHEEEHHEST------WSD-------AYPYSKRMAEKAVLAANGSILKN 176

  Fly   197 QKEYLATSAMRAPLTYGECDSHFITEIFDFLSTRGWVFPRIAGVGGKQQL---VYAGNVAWGHIC 258
            ... |.|.|:|....|||........|...|..:|     |..|.||..:   ||.|||||.||.
  Rat   177 GGT-LHTCALRPMYIYGERSPFLSVMILAALKNKG-----ILNVTGKFSIANPVYVGNVAWAHIL 235

  Fly   259 AYKALKVSDKA--VNGLPVFVTDDT---GINDVSRFVQKMAVLGERFKVK-TSWWYVPHFLFFFL 317
            |.:.|:...|:  |.|...:::|||   ..:|::      ..|.:.:.:: .|.|.:|..|.::|
  Rat   236 AARGLRDPKKSQNVQGQFYYISDDTPHQSYDDLN------CTLSKEWGLRLDSSWSLPLPLLYWL 294

  Fly   318 AFLLEVVVRVAYPYTKYRLRYSLRAIASYTSSMLMYNRLRASIHMDYMPLFDPDASAERSAKWYA 382
            |||||.|..:..|:..||..::.. :.:.::|...::..:|...:.|:||...:.:.:::::|..
  Rat   295 AFLLETVSFLLRPFYNYRPPFNCH-LVTLSNSKFTFSYKKAQRDLGYVPLVSWEEAKQKTSEWIG 358

  Fly   383 TWWDQRQQAQKLK 395
            |..:|.::....|
  Rat   359 TLVEQHRETLDTK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7724	NP_648957.1	Rossmann-fold NAD(P)(+)-binding proteins	8..381	CDD:473865	110/387 (28%)
Hsd3b1	NP_001007720.3	Rossmann-fold NAD(P)(+)-binding proteins	5..357	CDD:473865	110/387 (28%)