Protein Alignment CG7724 and Hsd3b5

DIOPT Version :10

• Sequence 1: NP_648957.1
• Gene: CG7724 / 39918
• FlyBaseID: FBgn0036698
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_036716.2
• Gene: Hsd3b5 / 24470
• RGDID: 2838
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 407
• Identity: 113/407 - (27%)
• Similarity: 191/407 - (46%)
• Gaps: 63/407 - (15%)

  Fly    10 LVTGGSGFLGQHLIKQLLERKEELGIKEIRSLDIVPYKN-NIGH-EETSLLRT--YVADIGGDL- 69
            ||||..|||||.:::.|::.||   ::|:|.|    |:. :..| ||.|.|:|  .|..:.||:
  Rat     7 LVTGAGGFLGQRIVQMLVQEKE---LQEVRVL----YRTFSPKHKEELSKLQTKAKVTVLRGDIV 64

  Fly    70 --KALSPIFNGVDGVFHCAASVKIE-YPPNYEELERVNVNGTLAVVDLCIQNNVKRLVYTSCTSV 131
              :.|.....|:..:.|.||::.|. :.|....|: |||.||..::|.|::.:|...:|:|.|.|
  Rat    65 DAQFLRRACQGMSVIIHTAAALDIAGFLPRQTILD-VNVKGTQLLLDACVEASVPAFIYSSSTGV 128

  Fly   132 CFVPFKGRSTF-SAVINSTESKTDTPTLDSSTLWEQDNQFLIPGYASSKLRAENIVLNSNGAPLH 195
            .     |.::: ..::|..|.:....|      |...       |..||..||..||.:||:.|.
  Rat   129 A-----GPNSYKETILNDREEEHREST------WSNP-------YPYSKRMAEKAVLAANGSILK 175

  Fly   196 NQKEYLATSAMRAPLTYGECDSHFITEIFDFLSTRGWVFPRIAGVGGKQQLVYAGNVAWGHICAY 260
            |... |.|.|:|.|..||| :|..|:.:.:.......:..|.|....... ||.||.||.||.|.
  Rat   176 NGGT-LHTCALRLPFIYGE-ESQIISTMVNTALKNNSIIKRHATFSIANP-VYVGNAAWAHILAA 237

  Fly   261 KALKVSDK--AVNGLPVFVTDDT---GINDVSRFVQKMAVLGERFKVKTSW-------WYVPHFL 313
            :.|:..:|  ::.|...:::|||   ..:|::            :.:...|       |.:|..|
  Rat   238 RGLRDPEKSQSIQGQFYYISDDTPHQSYDDLN------------YTLSKEWGFCLDSSWSLPLPL 290

  Fly   314 FFFLAFLLEVVVRVAYPYTKYRLRYSLRAIASYTSSMLMYNRLRASIHMDYMPLFDPDASAERSA 378
            .::||||||.|..:..|:..||..:: |.:.:..:|:...:..:|...:.|.||...:.:.::::
  Rat   291 LYWLAFLLETVSFLLRPFYNYRPPFN-RFMVTILNSVFTISYKKAQRDLGYEPLVSWEEAKQKTS 354

  Fly   379 KWYATWWDQRQQAQKLK 395
            :|..|..:|.::....|
  Rat   355 EWIGTLVEQHRETLDTK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7724	NP_648957.1	Rossmann-fold NAD(P)(+)-binding proteins	8..381	CDD:473865	109/391 (28%)
Hsd3b5	NP_036716.2	Rossmann-fold NAD(P)(+)-binding proteins	5..357	CDD:473865	109/391 (28%)