DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rogdi and ROGDI

DIOPT Version :9

Sequence 1:	NP_730244.1	Gene:	rogdi / 39917	FlyBaseID:	FBgn0036697	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	XP_006721010.1	Gene:	ROGDI / 79641	HGNCID:	29478	Length:	294	Species:	Homo sapiens

Alignment Length:	287	Identity:	112/287 - (39%)
Similarity:	153/287 - (53%)	Gaps:	38/287 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 MLADTEREEALNLQIEFEWVLRQEVHAILKQLRSILVECAHRFPVPLYENEG-KKTEKFIL-TVS 140
            ::|.|..|.|: |:.||.|:|..||||:||||:.||.|.:.||.:|....|| .|.|.||| :..
Human     4 VMAATAAERAV-LEEEFRWLLHDEVHAVLKQLQDILKEASLRFTLPGSGTEGPAKQENFILGSCG 67

  Fly   141 PDQLKAVLTLTGDAITQADISFKLCKAPSQTQRTSITHDSPWKLQQVQDAANHLQTAINHIDDVD 205
            .||:|.||||.|||::|||::.|:.: .:|....:...|..|||||:|||.||:..||..:...|
Human    68 TDQVKGVLTLQGDALSQADVNLKMPR-NNQLLHFAFREDKQWKLQQIQDARNHVSQAIYLLTSRD 131

  Fly   206 DSYHFKTSDEVLHVIGNILDALQRGRNSLLVPKKKPIDELIKGRNMKSLVPNLPEDLAVSFYLQS 270
            .||.|||..|||.::..::..|.|.||.|..|....:.|:......:...|.||.||.|:.|:..
Human   132 QSYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPALPSDLLVNVYINL 196

  Fly   271 HKLIIAVYQL------------------LNNQGTM--------RFDSRQAEAS--------VQWL 301
            :||.:.||||                  |::.|.|        .:.|::.|.|        :.||
Human   197 NKLCLTVYQLHALQPNSTKNFRPAGGAVLHSPGAMLDPLTAHSEWGSQRLEVSHVHKVECVIPWL 261

  Fly   302 NDVLLLLMNGQKLCQQLKDKISVFSVY 328
            ||.|:......:|||||||||||||.|
Human   262 NDALVYFTVSLQLCQQLKDKISVFSSY 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rogdi	NP_730244.1	Rogdi_lz	93..>280	CDD:287261	80/188 (43%)
ROGDI	XP_006721010.1	Rogdi_lz	18..283	CDD:287261	101/265 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146864
Domainoid	1	1.000	144	1.000	Domainoid score	I4639
eggNOG	1	0.900	-	-		E1_KOG3992
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11605
Inparanoid	1	1.050	173	1.000	Inparanoid score	I4092
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46596
OrthoDB	1	1.010	-	-		D1051737at2759
OrthoFinder	1	1.000	-	-		FOG0007220
OrthoInspector	1	1.000	-	-		oto89860
orthoMCL	1	0.900	-	-		OOG6_107253
Panther	1	1.100	-	-	LDO	PTHR13618
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2769
SonicParanoid	1	1.000	-	-		X6095
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800