DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rogdi and H14A12.3

DIOPT Version :9

Sequence 1:	NP_730244.1	Gene:	rogdi / 39917	FlyBaseID:	FBgn0036697	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_498641.1	Gene:	H14A12.3 / 176058	WormBaseID:	WBGene00019196	Length:	292	Species:	Caenorhabditis elegans

Alignment Length:	281	Identity:	79/281 - (28%)
Similarity:	130/281 - (46%)	Gaps:	35/281 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 PKSAM---KMLADTEREEALNLQIEFEWVLRQEVHAILKQ----------LRSILVECAHRFPVP 123
            ||.|.   :.:.||.|....|   |..|:.|::|...|:.          :.::..:|..|..|.
Worm    14 PKPASPNPQDIRDTIRSNKTN---ENLWIQRKDVDTTLRSALEHLKACCIVLNLSAKCDERLNVA 75

  Fly   124 LYENEGKKTEKFILTVSPDQLKAVLTLTGDAITQADISFKLCKAPSQTQRTSITHDSPWKLQQVQ 188
            :.....:|.:....|.|.|.|||.:||..|.:.||:::.|..||.....|.....|..|||||:|
Worm    76 VSHGTTEKYQLMSRTGSSDNLKAAVTLLDDNVIQAEVTVKYPKAGGGYYRAVAQPDVQWKLQQLQ 140

  Fly   189 DAANH----------LQTAINHI--DDVDDSYHFKTSDEVLHVIGNILDALQRGRNSLLVPKKKP 241
            |..||          ||..:|.:  |...|::...|...:|..:...::.:...|||:::|:|:.
Worm   141 DLGNHISRVTITLCDLQHEVNLLKGDGERDAFTLATGARILEELKLTMNEISLARNSIMLPRKRS 205

  Fly   242 IDELIKGRNMKSLVPNLPEDLAVSFYLQSHKLIIAVYQL----LNNQGTMRFDSRQAEASVQWLN 302
            :.||......:..||.||:|..:|||:...:|:.|.||:    ::.||...|   .||:.:..|:
Worm   206 LLELCYFPPTRKFVPPLPQDQLISFYISCCRLVCASYQMVPKTVHPQGLSVF---MAESQLPHLD 267

  Fly   303 DVLLLLMNGQKLCQQLKDKIS 323
            ||:..|.....:.|:|.:.:|
Worm   268 DVIKHLNTVMAILQKLINYLS 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rogdi	NP_730244.1	Rogdi_lz	93..>280	CDD:287261	59/208 (28%)
H14A12.3	NP_498641.1	Rogdi_lz	90..>251	CDD:287261	51/160 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159075
Domainoid	1	1.000	91	1.000	Domainoid score	I4875
eggNOG	1	0.900	-	-		E1_KOG3992
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I3606
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46596
OrthoDB	1	1.010	-	-		D1051737at2759
OrthoFinder	1	1.000	-	-		FOG0007220
OrthoInspector	1	1.000	-	-		oto20487
orthoMCL	1	0.900	-	-		OOG6_107253
Panther	1	1.100	-	-	LDO	PTHR13618
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2769
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.800