DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC73F and Efcab6

DIOPT Version :9

Sequence 1:	NP_001287091.1	Gene:	TpnC73F / 39916	FlyBaseID:	FBgn0010424	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	XP_006521594.2	Gene:	Efcab6 / 77627	MGIID:	1924877	Length:	1536	Species:	Mus musculus

Alignment Length:	164	Identity:	29/164 - (17%)
Similarity:	66/164 - (40%)	Gaps:	41/164 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DHQKTGSIPTEMVADILRLMGQ---PFDKKILEELIEEVDEDKSGRLEFGEFVQLAAKFIVEEDA 85
            |..|.|:|   ..|:.|.|:.:   ...::..::||.:.|...:|:..:.:|:|.....:..::.
Mouse  1371 DTDKQGTI---SAAEFLALVEKFKLDISREESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKET 1432

  Fly    86 EAMQ-----------------------------------KELREAFRLYDKQGNGFIPTTCLKEI 115
            ..|:                                   :.:|.:|:.|||.|.|.:.....:::
Mouse  1433 SLMRRMRIQNADKMKEAGMETPSFYSALLRIQPKIVHCWRPMRRSFKTYDKNGTGLLSVADFRKV 1497

  Fly   116 LKELDDQLTEQELDIMIEEIDSDGSGTVDFDEFM 149
            |::....|:|:|...::|..|...|..:.:::|:
Mouse  1498 LRQYSINLSEEEFFHVLEYYDKSLSSKISYNDFL 1531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC73F	NP_001287091.1	PTZ00184	6..153	CDD:185504	29/164 (18%)
Efcab6	XP_006521594.2	FRQ1	119..285	CDD:227455
		FRQ1	338..501	CDD:227455
		EFh_PEF	787..>952	CDD:355382
		EF-hand motif	787..823	CDD:320054
		EF-hand motif	828..889	CDD:320054
		EF-hand motif	890..922	CDD:320054
		EFh_PI-PLC	894..1004	CDD:333715
		EF-hand motif	894..922	CDD:320029
		EF-hand_7	898..952	CDD:372618
		EF-hand motif	929..954	CDD:320029
		EF-hand_11	1197..1301	CDD:370222
		PTZ00183	1364..1532	CDD:185503	29/164 (18%)
		EF-hand_7	1474..1534	CDD:372618	15/58 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838655
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930