DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC73F and CABP4

DIOPT Version :9

Sequence 1:	NP_001287091.1	Gene:	TpnC73F / 39916	FlyBaseID:	FBgn0010424	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	XP_011543483.1	Gene:	CABP4 / 57010	HGNCID:	1386	Length:	295	Species:	Homo sapiens

Alignment Length:	152	Identity:	57/152 - (37%)
Similarity:	88/152 - (57%)	Gaps:	4/152 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DEDLTPEQIAVLQKAFNSFDHQKTGSIPTEMVADILRLMG-QPFDKKILEELIEEVDEDKSGRLE 68
            |.:|.||::..||.||..||..:.|.|....:.|.:|.:| .|.:.::| |:.:.:.....||::
Human   143 DRELGPEELDELQAAFEEFDTDRDGYISHRELGDCMRTLGYMPTEMELL-EVSQHIKMRMGGRVD 206

  Fly    69 FGEFVQLAAKFIVEEDAEAM-QKELREAFRLYDKQGNGFIPTTCLKEILKE-LDDQLTEQELDIM 131
            |.|||:|....:.||.|..: .:|||.|||.:|:..:|.|....|:|.:.. |.:.|...|||.|
Human   207 FEEFVELIGPKLREETAHMLGVRELRIAFREFDRDRDGRITVAELREAVPALLGEPLAGPELDEM 271

  Fly   132 IEEIDSDGSGTVDFDEFMEMMT 153
            :.|:|.:|.||||||||:.|::
Human   272 LREVDLNGDGTVDFDEFVMMLS 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC73F	NP_001287091.1	PTZ00184	6..153	CDD:185504	56/149 (38%)
CABP4	XP_011543483.1	PHA03415	81..>190	CDD:177643	16/46 (35%)
		PTZ00184	145..294	CDD:185504	56/150 (37%)
		EFh	153..214	CDD:238008	20/61 (33%)
		EFh	230..293	CDD:238008	29/62 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340191at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920