DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC73F and Efcab6

DIOPT Version :9

Sequence 1:	NP_001287091.1	Gene:	TpnC73F / 39916	FlyBaseID:	FBgn0010424	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	XP_038936237.1	Gene:	Efcab6 / 315179	RGDID:	1309065	Length:	1509	Species:	Rattus norvegicus

Alignment Length:	169	Identity:	27/169 - (15%)
Similarity:	63/169 - (37%)	Gaps:	35/169 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LQKAFNSFDHQKTGSIPTEMVADILRLMGQPFDKKILEELIEEVDEDKSGRLEFGEFVQLAAKFI 80
            |.|.....|..|.|||.......::........::..::|:.:.|...:|:..:.:|:|.....:
  Rat  1336 LLKECKEKDTDKQGSITAAEFLALIEKFKLDISREESQQLLVKYDMKNNGKFAYCDFIQSCVLLL 1400

  Fly    81 VEEDAEAMQ-----------------------------------KELREAFRLYDKQGNGFIPTT 110
            ..::...|:                                   :.:|..|:.||:.|.|.:...
  Rat  1401 KAKETSLMRRMRIQNADKMKEAGVETPSFYSALLRIQPKIVHCWRPMRRTFKTYDENGTGLLSVA 1465

  Fly   111 CLKEILKELDDQLTEQELDIMIEEIDSDGSGTVDFDEFM 149
            ..:::|::....|:|:|...::|..|...|..:.:::|:
  Rat  1466 DFRKVLRQFSINLSEEEFFHVLEYYDKSLSSKISYNDFL 1504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC73F	NP_001287091.1	PTZ00184	6..153	CDD:185504	27/169 (16%)
Efcab6	XP_038936237.1	FRQ1	82..264	CDD:227455
		EFh_parvalbumin_like	<420..490	CDD:330177
		EF-hand motif	429..457	CDD:319994
		EF-hand motif	465..490	CDD:319994
		EFh_PI-PLC	869..980	CDD:333715
		EF-hand motif	869..897	CDD:320029
		EF-hand_7	873..927	CDD:404394
		EF-hand motif	904..929	CDD:320029
		FRQ1	1086..1247	CDD:227455
		EF-hand_11	1170..1274	CDD:401068
		PTZ00183	1335..1505	CDD:185503	27/169 (16%)
		EF-hand_7	1447..1507	CDD:404394	14/58 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342443
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930