DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Papst2 and Slc35b3

DIOPT Version :9

Sequence 1:	NP_648954.1	Gene:	Papst2 / 39914	FlyBaseID:	FBgn0036695	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_225253.5	Gene:	Slc35b3 / 306866	RGDID:	1307183	Length:	411	Species:	Rattus norvegicus

Alignment Length:	348	Identity:	199/348 - (57%)
Similarity:	254/348 - (72%)	Gaps:	13/348 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SQRKSSTSESPPELRILCFDLTYYNRTTQFLLSCAGVFFLYILYGYLQELIFTVEGFKPYGWFLT 97
            :|..|...:|..::.:|..:|:.:.:.||||:..||||..|::|||||||||::||||||||:||
  Rat    62 TQTMSPHIKSVEDVVVLGVNLSRFKKLTQFLICVAGVFVFYLIYGYLQELIFSMEGFKPYGWYLT 126

  Fly    98 LVQFGYYIGFGLVERRLEGYRISGGSFWNIEPEPRCIPMRTYLILAALTLGTMGLSNSSLGYLNY 162
            ||||.:|..|||:|.:|            .:.:.|.||.:||:|:|.||:|||||||:|||||||
  Rat   127 LVQFAFYSVFGLIELQL------------TQDKRRRIPGKTYMIIAFLTVGTMGLSNTSLGYLNY 179

  Fly   163 PTQVIFKCCKLIPVLVGSILIQGKRYGLLDFAAATCMCIGLAWFTLADSQMTPNFNLLGVAMISG 227
            ||||||||||||||::|.:.||||||.|.|.:||.||.:||.|||||||.:.|||||.||.:||.
  Rat   180 PTQVIFKCCKLIPVMLGGVFIQGKRYNLADVSAAVCMSLGLIWFTLADSTIAPNFNLTGVMLISL 244

  Fly   228 ALLCDAAIGNVQEKAMREFKAPSSEVVFYSYGLGFVYLFVIMLVTGNFFSGFAFCLEHPVETFGY 292
            ||..||.|||||||||:...|.:||:|.|||.:||||:.:.:..|.......|||.::||.|:||
  Rat   245 ALCADAVIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLGLSCTSGLGPALAFCSKNPVRTYGY 309

  Fly   293 GFLFSLSGYLGIQFVLALVRSSGAPIAATVTTARKAVTIAFSFVLFSKPFTLQYLWSGLIVVLGI 357
            .|||||:||.||.|||||::..||.:|.||||.|||:||..||:.|:||||.||:||||:|||||
  Rat   310 AFLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKAMTIVLSFLFFAKPFTFQYIWSGLLVVLGI 374

  Fly   358 YLNVYSKR-NKLTLADVRQRIKQ 379
            :||||||. :|:.|..|...||:
  Rat   375 FLNVYSKNMDKIRLPSVYSVIKK 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Papst2	NP_648954.1	UAA	61..364	CDD:285625	186/302 (62%)
Papst2	NP_648954.1	EamA	219..362	CDD:279264	84/142 (59%)
Slc35b3	XP_225253.5	UAA	90..381	CDD:285625	186/302 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340713
Domainoid	1	1.000	383	1.000	Domainoid score	I789
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9313
Inparanoid	1	1.050	395	1.000	Inparanoid score	I1902
OMA	1	1.010	-	-		QHG57264
OrthoDB	1	1.010	-	-		D1116466at2759
OrthoFinder	1	1.000	-	-		FOG0005379
OrthoInspector	1	1.000	-	-		oto98044
orthoMCL	1	0.900	-	-		OOG6_104682
Panther	1	1.100	-	-	LDO	PTHR10778
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3814
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770