Protein Alignment CG6652 and lca5

DIOPT Version :9

• Sequence 1: NP_648946.3
• Gene: CG6652 / 39905
• FlyBaseID: FBgn0036687
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_009295281.2
• Gene: lca5 / 100151323
• ZFINID: ZDB-GENE-090313-268
• Length: 767
• Species: Danio rerio
• Alignment Length: 629
• Identity: 143/629 - (22%)
• Similarity: 258/629 - (41%)
• Gaps: 116/629 - (18%)

  Fly     3 SPRKLASSYGPRVSQSEPNNLMAASAKSCESLFSASSRESASLIYQRSKPPPPQQRGGVKGSGSM 67
            |.|.|:.|..|...:...:..:::|......:...:||...|..:.      ||||.|...|.|:
Zfish    84 SDRSLSPSASPSPPRRGRSRRVSSSPLHKTGVHKGASRRILSHSHH------PQQRAGAIRSQSL 142

  Fly    68 S----SQNHSEIHQRVMSARNLRAKTFQNQLADAQAEIANLAHENRMLRTLHNRQSSALNKYEAH 128
            |    |::..::.:|::|||.|:....:|.|::.:.....|..|||:||.|..||..||::|...
Zfish   143 SKDAPSKDVDQVTKRMLSARLLKINELKNALSELRLHADELQRENRLLRQLQLRQEKALHRYNDT 207

  Fly   129 NAELPKLLSSHAEELRMWQTKYRKLQAANKALELKLKQKEEIILTLSDQNKHYSQLNKDKNLDER 193
            ::|:.:||:.|..|..:.:.:.|:.|...:..|..|::::..:.....|.:...||..|:||.||
Zfish   208 DSEISQLLARHNNETHVLRERLRRSQENQRTAERSLRERDAQLQRCRSQMQKLQQLADDQNLGER 272

  Fly   194 QKLQEKLKSLEQRLEEKDNDMKLMARKVQLESKNIRQQLLNEQRKGKEVMLKLEKAKLEISGY-- 256
            ::|..||...:.||::.::.:|.:.:.::|.|.:.::||.||:||..:...:::..:.|:...
Zfish   273 EELSRKLIGTQSRLQDSEHRVKELEKNMELSSGSFQRQLANERRKTHDAQQEVKALQEEVERLCT 337

  Fly   257 ------RKLEEYTLGTDKVNPLSS------GRRTKLSGVTDEPDKIDKLEKSMEMLDKAIEKNNQ 309
                  |:|:...:..::::..||      |.:.|...:|.        .|:::..|:....:..
Zfish   338 KLKEKERELDARNIYANRMHKASSRKEAENGSKRKGFNITS--------TKAVQTEDRTSSLDFP 394

  Fly   310 SEFTALTDVMESESFYDFEKDSAEDKSGPNTPPSQIERQVGGRGGKLILPPATNH--AKMGQKAN 372
            |...|||:                     |.||   :.|........:..|..||  .|..|::.
Zfish   395 SPPPALTN---------------------NLPP---DDQTDDYLSLKVQKPTVNHRVKKQDQQSR 435

  Fly   373 RSTLSQVLSAQGKISVSSGKSAKSRIAVAVPKMESVQVSKRREPETVSR-------LASAETKPK 430
            .....:  |.:.||.....:..|.|      .|||.: .:.:|.||:..       |...|.:..
Zfish   436 EHRTRE--SKEWKIQEFWREREKER------HMESAR-EQEKEKETLHERERQTELLKDVERQRL 491

  Fly   431 QKPL---EYEYEDDYEPAGEDGDDDAYGMMSKMCEGE-----------------EPQDNSEENAN 475
            .:.|   |..::.:......:.:|...||.....|.|                 |.||.::|...
Zfish   492 DQDLSSNEKNFKGNRVGLNREEEDRRIGMSVSQKEEEIQKQRELEEEQQKVRNREIQDYNQERVE 556

  Fly   476 ESSLLKYSAYMDNKSSEGDPLEESMEEYD-GTDGQQSQGSDDEDISVRA-PRLKENMSSLRKQIS 538
            |....|            :.|...|.|.| .|.||.|....|:..|||: |||.|     ::..:
Zfish   557 EERQRK------------EQLLAKMREIDIQTQGQDSDFFSDDTGSVRSPPRLSE-----QRNHN 604

  Fly   539 NDFK--ERESFLKTFCRQASNSNMRDDSASKKRNSIATGAAASS 580
            ..||  |.:..:.||.......::|..:.::..: :|.|:.|.|
Zfish   605 GFFKLTEPDENINTFSSGRRGGSLRAQAPNEDLD-LAFGSYAPS 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6652	NP_648946.3	Lebercilin	82..257	CDD:292252	49/182 (27%)
		GBP_C	<151..252	CDD:303769	26/100 (26%)
		coiled coil	239..250	CDD:293879	0/10 (0%)
lca5	XP_009295281.2	Neuromodulin_N	<143..566	CDD:331332	101/475 (21%)
		Lebercilin	161..340	CDD:317931	49/178 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595523
Domainoid	1	1.000	98	1.000	Domainoid score	I7127
eggNOG	1	0.900	-	-		E1_28I5W
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004975
OrthoInspector	1	1.000	-	-		oto39872
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16650
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5200
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.830