Protein Alignment CG7728 and bms1

DIOPT Version :9

• Sequence 1: NP_648945.1
• Gene: CG7728 / 39904
• FlyBaseID: FBgn0036686
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_595102.2
• Gene: bms1 / 2540390
• PomBaseID: SPBC31E1.06
• Length: 1121
• Species: Schizosaccharomyces pombe
• Alignment Length: 1204
• Identity: 485/1204 - (40%)
• Similarity: 688/1204 - (57%)
• Gaps: 140/1204 - (11%)

  Fly     8 DKRKQHRARQSGVKADKKKLKAKKDSNQKEPELTARQRNPKAFAINSAQRAERNFRRKEDLTAKK 72
            |::|.|.|:.||.||:|||||...|.        :...||||||:.||.|..|...|..|::.||
pombe     2 DEKKGHYAKHSGPKAEKKKLKKVSDG--------SASNNPKAFAVASAGRMARQAMRTADISQKK 58

  Fly    73 QHIPVVDQTPN-VPPPVLIAVVGPPKVGKTTLIKDLIKSFTRTNVTDIKGPITIVTSKKRRITLL 136
            .|:|:||:||: .||||::||:|||..||:||||.|::.:::..::.|.||||:|..||||||.|
pombe    59 LHVPMVDRTPDEAPPPVIVAVMGPPGTGKSTLIKSLVRRYSKYTISQITGPITVVAGKKRRITFL 123

  Fly   137 ECNNDVNSMIDVAKCADLVLLLCDASYGFEMEIFEFLNICQVHGMPKIMGVLTHLDMIKNPKQLR 201
            ||.||::|||||||.|||||||.||::|||||..|||||...||||:|||||||||:.|....||
pombe   124 ECPNDLSSMIDVAKIADLVLLLIDANFGFEMETMEFLNILAPHGMPRIMGVLTHLDLFKKTSTLR 188

  Fly   202 KRKKELKHRFWTEVYDGAKLFYLSGLLHGEYLRNEVKNLGRFISVMKFRPLQWRGAHSYLLVDRI 266
            :.||.||||||||:|.|||||||||:|:|.|...|:.||.|||||||||||:||..|.|||.||:
pombe   189 EAKKRLKHRFWTELYQGAKLFYLSGVLNGRYPDREILNLSRFISVMKFRPLRWRNQHPYLLADRM 253

  Fly   267 EDVTNTDRVRRDPKCDREVVLYGYVRGVPL-KQEHMVHIAGLGDARIDELNVIPDPCPLPGTEK- 329
            ||:|....:.::||..|::.||||:.|..| |.:..|||.|:||....:::.:.||||.|..:|
pombe   254 EDLTLPVDIEQNPKVGRKITLYGYLHGTNLPKHDASVHIPGVGDFVTSDVSSLEDPCPPPDADKV 318

  Fly   330 -KRSLLEKERLLYAPMSGVGGIVYDKDAVYIELQGSHSHKEQEQTAEAAEQAELVNKLIDKKATI 393
             :|.|.||::|:|.||:.:|||::|||.||||:..|:..|::...|...|:..:..:...:...:
pombe   319 RRRRLSEKQKLIYGPMADIGGILFDKDRVYIEVPTSNFSKDENSEAGFGERMVMQLQEAQQPLGV 383

  Fly   394 DEQMEQQEFRLFSDAKPIKSKDFRNDQDDEEEDEEAESSENE-----------DDDG--EDSGLD 445
            |.....|   |||::..|.:.    |::..|.|.....:..:           :|:|  :||.::
pombe   384 DGNSGLQ---LFSNSDAIDTV----DRESSEIDNVGRKTRRQPTGLINQELIKEDEGAFDDSDVN 441

  Fly   446 AADSEEEQQDEFDADDWRGE----NSEEEEDAEEDASSGDEEYQSLGNVKTSNESDS------DD 500
            :||..|:.       |:.|:    |:|:|.|.||.|.:               :|||      ||
pombe   442 SADENEDV-------DFTGKIGAINNEDESDNEEVAFA---------------DSDSDLGGQFDD 484

  Fly   501 EEARVLASNMSWKTNLAQKARDAFLQRHSESKNLMRLVY--GVYNQSEHSRQEAEAEDDSEEEL- 562
            |:     ||:.||..||.||..|:.|.....:|:.::.|  .:..:..::..:.|:...||.:|
pombe   485 ED-----SNLRWKEGLASKAALAYSQSGKRRRNIQKIFYDESLSPKDAYAEYKGESAKSSESDLV 544

  Fly   563 -----GGLFRVAAKKQSLKQSDQDIRDKDERCFFEYQGDATRDWLAEDNKEL---IKNCFVTGKW 619
                 ...|:|:      |.:::.|....|:.........::.|   :|.:|   :|:.|:||..
pombe   545 VSDDEEDFFKVS------KVANESISSNHEKLMESESDRLSKKW---ENPQLLAQLKSRFITGSL 600

  Fly   620 KASEDAENLLKMDDMSDAESEVYGDFEDLETGEQHSGKPKAEDGGES---EEENSKPEDSSAPKR 681
            ..|.:.:..:..||..       |||||||..|..|.....|..|.|   |.|.|..|.....:|
pombe   601 LDSIEGQEEVSQDDEE-------GDFEDLEDEENSSDNEMEESSGSSVTAENEESADEVDFQTER 658

  Fly   682 KLTRVEEENLTKAELMAKKLKLKAKFDAEYDNSGEGKGEEDNGRITGDHSFYEDLKAEAQRQSEL 746
                  |||..|.|      :|:.:|:.|.....|.|          |..:|.:.|.:..||..:
pombe   659 ------EENARKKE------ELRLRFEEEDRGDPEKK----------DVDWYTEEKEKIARQLVI 701

  Fly   747 NKSEFAHLDNEFRIQIEGYRPGLYVRLGFKQLPAEFIENFDASYPVLVGALNMTEENVGYVNCKV 811
            |:..|..:|.|.|.:|||||.|.|||:....:|.||:|:||:.|||:||.|...|:..|.|..::
pombe   702 NREAFEDMDPESRAEIEGYRAGTYVRIVINDVPFEFVEHFDSRYPVVVGGLLPNEQRYGLVQVRI 766

  Fly   812 KKHRWYKKILKTGDPLIISMGWRRFQTVAIYAKVEDNFRQRYLKYTPNHVTCSMTFWGPITPQNT 876
            |:|||:||||||.||||.||||||||::.:|:..:...|.|.|||||.|:.|..||:||....|:
pombe   767 KRHRWHKKILKTNDPLIFSMGWRRFQSIPVYSISDSRTRNRMLKYTPEHMHCFGTFYGPFVAPNS 831

  Fly   877 GFLALQTVRQDQEEMRRLG-FRIAATGCVTEVDKSSQIMKKLKLVGHPFKIYKKTAFVKDMFNSS 940
            ||.|:|:|   .....:.| |||||||.|..:|:|:.|:|||||.|.|:||:|.|||:|.||:|.
pombe   832 GFCAVQSV---ANSFAKAGSFRIAATGSVLNIDQSTDIVKKLKLTGVPYKIFKNTAFIKKMFSSP 893

  Fly   941 LEVAKFEGAKIKTVSGIRGQIKKAHHTPEGSYRATFEDKILLSDIVFCRTWFRVEVPRFYAPVSS 1005
            |||||||||.|:||||||||:|||.....|.:|||||||||:|||||.|.|:.|:|.:|...|::
pombe   894 LEVAKFEGANIRTVSGIRGQVKKAVDQEHGHFRATFEDKILMSDIVFLRAWYPVQVRKFCTMVTN 958

  Fly  1006 LLLPLDQKSQWQGMKTLGQLKRERAVQNAAQPDSMYTTIVRKEKIFRPLTIPKALQRALPYKDKP 1070
            ||  ...|::|.||:..|:::.|..::...:|:|.|..|||..:.|.||.:|.:||..||:..:.
pombe   959 LL--ETDKTEWNGMRLTGEVRHELGLKTPLRPNSQYQEIVRPSRHFNPLKVPASLQAQLPFNSRQ 1021

  Fly  1071 K-LGPENPKAALERVAVVNSPYEQKVSKMMKMIETNFKDK-----------RQRERMEMKKRIKN 1123
            | |.|.:....:::..|:.:..|:||..:::.:.|...||           .:|....|:|..:.
pombe  1022 KALRPRSKPTYMQKRTVLLNAEERKVRDLLQKVMTLHTDKEAKRKAKKAAEHERYHKRMQKEEQA 1086

  Fly  1124 YREKKREKMASQ-ERRQKELRKKVSRAISKLRGK 1156
            |.|||||:.|.. .:..|.||:..:.:.|..|.|
pombe  1087 YIEKKREEKAEWFAQHGKRLRQDGNSSGSGKRSK 1120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7728	NP_648945.1	BMS1	34..1140	CDD:227519	465/1160 (40%)
		BMS1	49..279	CDD:206669	140/230 (61%)
		RIBIOP_C	707..994	CDD:282764	147/287 (51%)
bms1	NP_595102.2	BMS1	1..1105	CDD:227519	479/1187 (40%)
		BMS1	35..266	CDD:206669	140/230 (61%)
		RIBIOP_C	686..947	CDD:282764	142/263 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	295	1.000	Domainoid score	I268
eggNOG	1	0.900	-	-		E1_COG5192
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7065
Inparanoid	1	1.050	803	1.000	Inparanoid score	I66
OMA	1	1.010	-	-		QHG53908
OrthoFinder	1	1.000	-	-		FOG0005253
OrthoInspector	1	1.000	-	-		oto100898
orthoMCL	1	0.900	-	-		OOG6_102112
Panther	1	1.100	-	-	LDO	PTHR12858
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R142
SonicParanoid	1	1.000	-	-		X3775
TreeFam	1	0.960	-	-
	14	13.860