Protein Alignment CG3764 and fnip2

DIOPT Version :9

• Sequence 1: NP_001261977.1
• Gene: CG3764 / 39902
• FlyBaseID: FBgn0036684
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_021331522.1
• Gene: fnip2 / 797213
• ZFINID: ZDB-GENE-090312-31
• Length: 904
• Species: Danio rerio
• Alignment Length: 1425
• Identity: 297/1425 - (20%)
• Similarity: 473/1425 - (33%)
• Gaps: 597/1425 - (41%)

  Fly    84 TKQTSR----------NYLSRFPFEGSQVRVLLYKEDDT--RRLLFDSNALQKVMHKDQSATSAS 136
            ||.|||          |..:...|:.:|:|:::|::.:.  |::||||.|:.|:   |.|..:|.
Zfish    28 TKTTSRWLFIHEDASWNSWASAEFDLAQIRLIVYQDCERRGRQVLFDSKAIHKL---DASEPTAD 89

  Fly   137 ISSTSTSGGGKFLKNEKYTSLQNGKIPSKSHSSN-GSNFIEVCAEYGYKHNRPSGADITPVGEMV 200
            .:.|.                     |::|.:.: ||...|......|::.||: :|:..:|||:
Zfish    90 ETKTP---------------------PNRSGACHIGSQANEKDKPPTYQYTRPA-SDVNMLGEMM 132

  Fly   201 FGSLPMSFCGTALKVHWLPEPSRILCSQVYLTP-TSNGGSGHSPYSTLSTNSLATPRTSICSEHG 264
            |||:.||:.|:.||:|.:..|.:::.|:|:.|. .|:..||       |||:|          ..
Zfish   133 FGSVSMSYKGSTLKIHHIRSPPQLMVSKVFSTRFGSSSTSG-------STNTL----------QD 180

  Fly   265 SMDGLSMNSFSMPFSVSVG-RQMSLTPPLDV---------PATPADQQSLSIHSIDSSGPRYSST 319
            |.:.:| .:|....|.|:| |.:...|.|.:         .:.|.|..|.. ||.|.
Zfish   181 SFESMS-QTFPSHTSSSIGVRHVPSAPLLSLVRSASFFAAHSNPVDMPSRG-HSEDG-------- 235

  Fly   320 YSTATDSGYSASGSGSAAGGDQWSYQYSSTRSSLGSVLSDQSDAMRKLSMDLACYTGSPYLDGFA 384
                 |||.:.|                   :||.|:|:....:           .||.:..|.|
Zfish   236 -----DSGIARS-------------------ASLSSLLATPQPS-----------PGSSFSSGCA 265

  Fly   385 SDGCLQRRISRNLRTSFENEHSKNDFIGFLSDNYALNGPVVAPAGGGAGGGSEGGGMAPPQYRRA 449
            |.  .|||..|:..||.:                  :||:                   |::...
Zfish   266 SS--YQRRWLRSQATSLQ------------------HGPM-------------------PRWNAE 291

  Fly   450 SY--CANET-RSNPEMGRRQANLRRRAKLGLAVCISMSESFEEE---MELFCSEHIALLESMLSR 508
            ..  .::|: .|||.|.||:       |:.:::.||:.|..||.   .|.|.| |..|.||.:::
Zfish   292 EMFNLSDESCSSNPAMIRRK-------KIAISIIISLPEREEENHNFQEFFFS-HFPLFESHMNK 348

  Fly   509 LRASTELAYINHKN----------FLQIMFQAWQDTQQWFSDLFTAPRIKTPVWLSITTSGSKYS 563
            |:.:.|.|.|..:.          :|..:.:|..:.:....:|:.||||..|||||: .|.|...
Zfish   349 LKTAIERAMIVCRRIAESSQRVQVYLCRVMEALGEFRMTVWNLYMAPRISEPVWLSM-ISQSAER 412

  Fly   564 KTVAERFIKELCDLLSFADTKDSNFFISTMLTGILTHHLGWVATVSAFNSSGSKRSESSASAAAI 628
            ..:.:||:||: .||.....|..  |:|.:||.:|||||.||.||...|....|.:....::..:
Zfish   413 NLLCQRFLKEM-SLLMEHGVKSQ--FLSALLTAVLTHHLAWVPTVMPSNLPPIKPACQKPTSQTV 474

  Fly   629 EQRAKLLQVAQKHPYNALWAQLGDLYGAIGMPPKLARTIVCGAEKLWVEKLLNVLTYFIRCSEVR 693
            :..||      .||||.|||||||||||:|.|.::.||:|.|..:..|:::|.:|:||||||
Zfish   475 DLLAK------SHPYNPLWAQLGDLYGALGSPVRVCRTVVVGRRRELVQRVLYILSYFIRCS--- 530

  Fly   694 RAAKREDFNKQLINDLAAQSQTKNQTGTQERHKSPPTQKRGLSRAATCKQNLNAIADDADDENGE 758
                          ||....|.:.|........:.||.....:....|::......|......|
Zfish   531 --------------DLQEHVQPQGQKDNPANPCTSPTTDPNPASERICEKTFPPPPDTIKPIPG- 580

  Fly   759 LNMYDRDNEDGDPDGLDSGSLDASDGMQTLKKNEIPTVLAFRDSHFVQQELRIGNYLMDTGIDKK 823
                                        |..:....||.|  |:|
Zfish   581 ----------------------------TFMEQNDETVSA--DTH-------------------- 595

  Fly   824 MLLARQAQQYFRTGKDGRIRLTVTTPDNVELCMEEEQSSGTGSVSTGSVDDGAIEAIDYEDNVEA 888
                                 :..||..:|..|...:.:..|....|       |.:|
Zfish   596 ---------------------STNTPTGLEASMVRPECTEMGPECFG-------EHVD------- 625

  Fly   889 PPKKNFFWNMVPVAGVKEGLSLSDLAKLQQGIRIINRKLERRSSSYSVEGNPDQQQSKTGETGVG 953
                                                          ||.|
Zfish   626 ----------------------------------------------SVGG--------------- 629

  Fly   954 DFEPLSHERRASHLSLSDLITQNSMGKSDRMTWGIEPIKENVS-LEEQIHFDHCHKLIEREHGIC 1017
                                             |:|.|..|.| |.:::.|.
Zfish   630 ---------------------------------GLEHILANQSPLPQRVQFH------------- 648

  Fly  1018 RQTSADNGNGVVFVLGDNEPLINLKKSSEDLSGDQDSKPTLMLCAQHQRTHDRSKHSGMKFNFEQ 1082
                          :|....:.|:.::...:.|.|.....|     |||
Zfish   649 --------------IGSPREVENVGQAGGLMCGGQGLDRKL-----HQR---------------- 678

  Fly  1083 YPQIATNYMKNKNLLMSNYDLLMDKVTKLEASEAAALKGSDSTATLAASSSSTAALLPPTTPVTA 1147
                                 |:..:.:.|:|: :||..||...|
Zfish   679 ---------------------LLTDIRRNESSD-SALGDSDDEET-------------------- 701

  Fly  1148 NSDRCVVCSSGVGINTSATWNQTPSNATELEFETDEMHCYNQSGNGNGFSSKALQSVNSAASIDT 1212
             |.|                               ||:
Zfish   702 -SSR-------------------------------EMY--------------------------- 707

  Fly  1213 LKSSVAVEPPTPTIPTQMQTTYMRKQQPKRVPSGRSSVSSVAAKCAAVNVSQQLLKLPVPGIKEL 1277
                :|.|          ||.|       .:|...|.|.|    .|:||
Zfish   708 ----MAAE----------QTEY-------ELPLPSSQVES----RASVN---------------- 731

  Fly  1278 PQDDESPGDQLRAGFIPSLLLSVSDHYVSDMVLQGTCAPPNKWEMHLRE----DLALAARSASLI 1338
                 ..|..|..|:.|        .|:.|..|.|..:     ::.|::    ||.......:|.
Zfish   732 -----HFGRSLLGGYCP--------QYMPDFALHGISS-----DLRLKQCLMADLEHTVLHPALD 778

  Fly  1339 SQPAENIAIVADMDKWDVRLISSQTQQFPYAGGQ-SSPVGMSQLVSSMLETVQAMNAGGIPAYEC 1402
            ...||.:.||||.|:..|::::||.:.  ..||: ...|.:|.|:.:::.:|..:.|..|.|..|
Zfish   779 EPVAEALCIVADTDRLSVQVVTSQRRM--CEGGRLGRDVMVSNLIHTLITSVLQLYALNIAADFC 841

  Fly  1403 LSFLESKLQEIYLQSETLAAFLLETDPCRLSDITNPLQLSENDVPLLLSIAYIHTPKISR 1462
            :..||.:|||:|.:|.:||.:|.......:.::...|.:..:|:|||.::|..|:|.:::
Zfish   842 VMHLEDRLQEVYFKSRSLAEYLRGQTRVHVKELGLALGIESSDIPLLAAVASTHSPYVAQ 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3764	NP_001261977.1	FNIP_N	101..222	CDD:291310	35/123 (28%)
		FNIP_M	461..692	CDD:291311	88/243 (36%)
		FNIP_C	1269..1460	CDD:291312	50/195 (26%)
fnip2	XP_021331522.1	FNIP_N	55..154	CDD:317083	35/123 (28%)
		FNIP_M	299..532	CDD:317084	92/267 (34%)
		FNIP_C	717..900	CDD:317085	57/222 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584215
Domainoid	1	1.000	136	1.000	Domainoid score	I4877
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	247	1.000	Inparanoid score	I3247
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D156423at33208
OrthoFinder	1	1.000	-	-		FOG0002940
OrthoInspector	1	1.000	-	-		otm26408
orthoMCL	1	0.900	-	-		OOG6_104859
Panther	1	1.100	-	-	LDO	PTHR21634
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5679
SonicParanoid	1	1.000	-	-		X2303
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.020