Protein Alignment CG3764 and LOC3290069

DIOPT Version :10

• Sequence 1: NP_001261977.1
• Gene: CG3764 / 39902
• FlyBaseID: FBgn0036684
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_061504922.1
• Gene: LOC3290069 / 3290069
• VectorBaseID: AGAMI1_008793
• Length: 1418
• Species: Anopheles gambiae
• Alignment Length: 1628
• Identity: 505/1628 - (31%)
• Similarity: 738/1628 - (45%)
• Gaps: 458/1628 - (28%)

  Fly    76 NSSSSAKATKQTSRNYLSRFPFEGSQVRVLLYKEDDT--RRLLFDSNALQKVMHKDQSATSASIS 138
            |:|||::.|..      .:|||...|||:|::||.|.  |:|||||:.::||.....||.:|:..
Mosquito    15 NTSSSSQKTSP------GQFPFSADQVRILVFKECDIRGRKLLFDSSTVEKVSSDSNSAAAAAAF 73

  Fly   139 STSTSGGGKFLKNEKYTSLQNGKIPSKSHSSNGSNFIEVCAEYGY-----KHNRPSG-----ADI 193
            ::                         .|.......::.|.....     |||.|..     .:|
Mosquito    74 AS-------------------------DHHPPSVPQVQKCEHCNVVYRVRKHNDPRSEAVLKTEI 113

  Fly   194 TPVGEMVFGSLPMSFCGTALKVHWLPEPSRILCSQVYLTPTSNGGSGHS----PYSTLSTNSLAT 254
            ....||||||.|::|.|::.|||||..|..::||.|:.||..||....|    |.|.|..|..::
Mosquito   114 KQFEEMVFGSAPIAFRGSSFKVHWLKAPKTLMCSLVFPTPVYNGVKKSSVSTYPGSELFINGSSS 178

  Fly   255 PRTS--ICSEHGSMD-GLSMNSFSMPFSVSVGRQMSLTPPLDVPATPADQQSLS-IHSIDSSGP- 314
            ..|:  |.|..|.:| ..|::..|   |:..|...|.|    |.::.|.|...| :|.:....|
Mosquito   179 GNTTSGIGSSSGGVDYNPSVSDLS---SIGTGSLHSFT----VSSSTATQHDPSLLHRLRPVLPV 236

  Fly   315 -----------RYSSTYSTATDSGYSA------SGSGSAAGGDQWSYQYSSTRSSLGSVLSDQSD 362
                       |:||  ::..||||..      |||||:.....     ||.||||.|:.|| .|
Mosquito   237 EFCNFDRFADMRHSS--NSGVDSGYGGTDPWGLSGSGSSRHPTS-----SSHRSSLSSIYSD-FD 293

  Fly   363 AMRKLSMDLACYTGSP-----YLDGFASDGCLQRRISRNLRTSFENEHSKNDFIGFLSDNYALNG 422
            .:|::|.|.......|     .|:...|.|...||:|:||.|||||.|:..|.:|.|.:    .|
Mosquito   294 CIRRMSTDNFSVDIPPPPNCVSLEDCHSYGSFHRRVSKNLSTSFENRHTVADHVGHLDE----LG 354

  Fly   423 PVVAPAGGGAGGGSEGGGMAPPQYRRASYCA---------NETRSNPE----MGRRQA------- 467
            .::|   ||.|||:.|||:.  |:..|:..:         :..|.|.|    |.||:|
Mosquito   355 QMMA---GGGGGGAGGGGVG--QHAGATVTSAAASDGCVVSRNRRNSETMELMNRRKAYSGELLS 414

  Fly   468 ---NLRRRA-----KLGLAVCISMSESFEEEMELFCSEHIALLESMLSRLRASTELAYINHKNFL 524
               |.:.:|     :||:||||.::|...::.:.|||||:.:.||:|.|:|.:.|.|||..:.||
Mosquito   415 TATNYQGKAPSKKQRLGVAVCIRLNEVMLQDTDTFCSEHMTVFESILCRVRVAVEKAYIRWRLFL 479

  Fly   525 QIMFQAWQDTQQWFSDLFTAPRIKTPVWLSITTS--GSKYSKTVAERFIKELCDLLSFADTKDSN 587
            |||..||..||||.:|||||||:..||||::::|  ..:...::|..|:.:||.|||.|||||:|
Mosquito   480 QIMLGAWHSTQQWLNDLFTAPRLNNPVWLTLSSSTLTDRNLASLASTFMNDLCSLLSSADTKDTN 544

  Fly   588 FFISTMLTGILTHHLGWVATVSAFNSSGSKRSESSASAAAIEQRAKLLQVAQKHPYNALWAQLGD 652
            ||||||:|.:||||||||.|::|..::... |.||.......::.::.::...|||:.|||||||
Mosquito   545 FFISTMITAVLTHHLGWVGTIAAMTATDDS-SPSSKLDLIRREKIRMNEITANHPYSVLWAQLGD 608

  Fly   653 LYGAIGMPPKLARTIVCGAEKL--WVEKLLNVLTYFIRCSEVRRAAKREDFNK---------QLI 706
            ||||:|.|.||::||:||:.:|  .::|:||||:|||||.|::|....|.|::         |..
Mosquito   609 LYGAVGYPTKLSKTIICGSSQLSNTLDKILNVLSYFIRCCEIKRTVYVESFDEANVRTAFIAQRA 673

  Fly   707 NDLAAQSQTKNQTGTQ-------ERH---------KSPP---TQKRGLSRAATCKQNLNAIADDA 752
            |..||.:.:....|..       ||.         ..||   :...|:.|:||..:||.::|..:
Mosquito   674 NAAAAAAASIPAEGMHDLKVPFAERSAGLLQPPAAPQPPLLRSASSGMVRSATRMKNLASLAGGS 738

  Fly   753 DDE-------NGELNMYDRDNEDGDPDGLDSGSLDASDGMQ-TLKK---NEIPTVLAFRDSHFVQ 806
            :.:       .|||.               |.:..|::.:| .|||   |:||.||.:|||.||:
Mosquito   739 EKDISQHTATTGELT---------------SATSPANEEVQKALKKNVMNDIPNVLVYRDSRFVR 788

  Fly   807 QELRIGNYLMDTGI-----DKKMLLARQAQQYFRTGKDGRIRLTVTTPDNVELCMEEEQSSGTGS 866
            |||||||..||||:     :|:.|.||     ::.||...::.|...|:
Mosquito   789 QELRIGNTSMDTGLVMNAREKQYLEAR-----YQIGKVALLQPTQADPE---------------- 832

  Fly   867 VSTGSVDDGAIEAIDYEDNVEAPPKKNFFWNMVPVAGVKEGLSLSDLAKLQQGIRIINRKLERRS 931
                                                             |.|...::..:.|.|.
Mosquito   833 -------------------------------------------------LAQEALVLEAEREGRC 848

  Fly   932 SSYSVEGNPDQQQSKTGETGVGDFEPLSHERRASHLSLSDLITQNSMGK---------SDRMTWG 987
            |:     :.|.::|                     :.||.|||:||:|:         ..|:.||
Mosquito   849 SA-----DGDDRES---------------------VRLSYLITENSLGQVGSSEAAESQQRLIWG 887

  Fly   988 IEPIKENVSLEEQIHFDHCHKLIEREHGICRQTSADNGNG-----VVFVLGDNEPL--INLKKSS 1045
            :|..||.::.|:..:.    .|:..::.:.:...::...|     ||||||:||.|  |:.|..:
Mosquito   888 VEKTKEGIAFEQLKYI----SLLRGDYQVQKDAVSEKDQGEPKSEVVFVLGENEMLKDIHRKAGT 948

  Fly  1046 EDLSGDQDSKPTLML------CAQHQRTHDRSKHSGMKFN-FEQYPQIATNYMKNKNLLMSNYDL 1103
            .|   |...:|..|:      |.|             ||| |::|.:||.|::|::||  .:|.|
Mosquito   949 PD---DDVLRPLGMVQPLKHCCRQ-------------KFNSFDRYRKIAANFLKSRNL--PDYHL 995

  Fly  1104 L-------MDKVTKLEASEAAALKGSDSTATLAASSSSTAALLPPTTPVTANSDRCVVCSSGVGI 1161
            |       :.:..:.||:.:.|.....|...:..|||||      ::...|....|.||..   |
Mosquito   996 LERGKGHALGEQEEPEAAISVAPLPELSFGVIEPSSSST------SSSRQAGKPECAVCHQ---I 1051

  Fly  1162 NTSATWNQTPSNATELEFETDEMHCYNQSGNGNGFSSKALQSVNSAASIDTLKSSVAVEPPTPTI 1226
            .| ....|||:||:|:|| ..|:     |.||   |.:...|..||    .|:.....||    :
Mosquito  1052 PT-VYCLQTPTNASEMEF-IGEL-----SPNG---SHRPYWSGRSA----LLEQLTGGEP----V 1098

  Fly  1227 PTQMQTT----------YMRKQQPKRVPSGRSSVS-----SVAAKCAAVNVSQQLLKLPVP---- 1272
            |.....|          .||:..|..|..|.:..:     .:.||.....:  :|:.:|.|
Mosquito  1099 PEDAACTTGGHPSGGLPLMRENIPLIVLLGHTMATLDENDELRAKHPGSIL--KLIDIPFPKGMR 1161

  Fly  1273 ----------------------------------GIKELPQDDESPGDQ---------------- 1287
                                              |:........:.|..
Mosquito  1162 TAAAGGHDENNNSNGTGSGCSVGGGGSGAVGGSHGVNNTGSAGSAGGGNSGGHSAASGHHHHTTD 1226

  Fly  1288 ----------------LRAGFIPSLLLSVSDHYVSDMVLQGTCAPPNKWEMHLREDLALAARSAS 1336
                            .|.||:|||...::|||:.|||||.|.|||.:||..|:.||.||||...
Mosquito  1227 ATGSTGSDKTEKGVRCFRTGFMPSLFSRITDHYMPDMVLQATTAPPAQWEAALKRDLHLAARFTL 1291

  Fly  1337 LISQPAENIAIVADMDKWDVRLISSQTQQFPYAGGQSSPVGMSQLVSSMLETVQAMNAGGIPAYE 1401
            ...|..||.||||::|..:|||:|||:..      ....||||||||||||.|.||.:.||.||:
Mosquito  1292 YEQQLTENNAIVANLDTHEVRLLSSQSLV------DGDIVGMSQLVSSMLEAVSAMWSAGISAYQ 1350

  Fly  1402 CLSFLESKLQEIYLQSETLAAFLLETDPCRLSDITNPLQLSENDVPLLLSIAYIHTPKISRKCGI 1466
            |::|:||||:|:||||||:|:.:|.||.|.||.||..:.::.||:.||||:|.:|||:.:::..:
Mosquito  1351 CMAFIESKLRELYLQSETIASVMLATDFCTLSSITTAMDITANDMELLLSVASVHTPEATKRYRV 1415

  Fly  1467 SFR 1469
            ..|
Mosquito  1416 LMR 1418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3764	NP_001261977.1	FNIP_N	101..226	CDD:464228	40/136 (29%)
		FNIP_M	461..692	CDD:434087	117/253 (46%)
		FNIP_C	1269..1461	CDD:464229	96/261 (37%)
LOC3290069	XP_061504922.1	None