Protein Alignment CG3764 and fnip1

DIOPT Version :10

• Sequence 1: NP_001261977.1
• Gene: CG3764 / 39902
• FlyBaseID: FBgn0036684
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: NP_001120937.2
• Gene: fnip1 / 324863
• ZFINID: ZDB-GENE-030131-3586
• Length: 1077
• Species: Danio rerio
• Alignment Length: 1485
• Identity: 327/1485 - (22%)
• Similarity: 521/1485 - (35%)
• Gaps: 527/1485 - (35%)

  Fly    78 SSSAKATKQTSRNYLSRFPFEGSQVRVLLYKEDDT--RRLLFDSNALQKVMHKDQSAT----SAS 136
            |..|:.:::.:....|....|.||:|:::|::.:.  |.:||||:| :|...:|..||    .|.
Zfish    17 SPPARCSREDTVFSWSSPELEPSQIRLIVYQDCERRGRNVLFDSDA-RKRSTEDGPATRVCGEAQ 80

  Fly   137 IS------STSTSGGGKFLKNEKYTSLQNGKIPSKSHSSNGSNFIEVCAEYGYKHNR-----PSG 190
            :.      ....:||.                 |.|..|:.|     ||....:.||     ...
Zfish    81 VKMFGRCCQLRPTGGS-----------------SSSLDSSSS-----CASEPKEQNRFQASSRCS 123

  Fly   191 ADITPVGEMVFGSLPMSFCGTALKVHWLPEPSRILCSQVYLTPTSNGGSGHSPYSTL-------- 247
            :|...:|||:|||:.||:.|:.||:|.:..|.:::.|:|:...|  |||.....:||
Zfish   124 SDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQMMLSKVFTART--GGSVCGSLNTLQDSLEFIN 186

  Fly   248 STNSLATPRTSICSEHGSMDGLSMNSFSMPFSVSVGRQMSLTPPLDV---------PATPADQQS 303
            ..:|...|..:..:.:|.:..:..:....|     .|.:|...||.:         .:.|.|...
Zfish   187 QDSSTLRPEQNHTAANGFLGSIGFSQLCSP-----RRALSEQGPLRLIKSASFFSGHSNPMDMPG 246

  Fly   304 LSIHSIDSSGPRYSSTYSTATDSGYSASGSGSAAGGDQWSYQYSSTRSSLGSVLSDQSDAMRKLS 368
            ..::....||...|::.|:...:.:.:.||                                  |
Zfish   247 RGLYDERDSGIARSASLSSLLITPFPSPGS----------------------------------S 277

  Fly   369 MDLACYTGSPYLDGFASDGCLQRRISRNLRTSFENEHSKNDFIGFLSDNYALNGPVVAPAGGGAG 433
            :..:|  .|.|          |||..|:..||.||
Zfish   278 LTSSC--ASSY----------QRRWLRSQTTSLEN------------------------------ 300

  Fly   434 GGSEGGGMAPPQYRRASYCANETRSNPEMGRRQANLRRRAKLGLAVCISMSESFEEEMEL--FCS 496
                  |:.|......|:..::..|.|.:|     :.|:.|:.:.|...:|.:.||..:.  |..
Zfish   301 ------GVFPRWSVEESFNMSDESSGPSLG-----VARKKKIAIGVIFQLSPNEEENTKFQDFFF 354

  Fly   497 EHIALLESMLSRLRASTELAYINHKNFLQI---------MFQAWQDTQQWFSDLFTAPRIKTPVW 552
            .|..|.||.:::|:::.|.|.|..:.....         |.....:.:....:|:|.||:..|||
Zfish   355 SHFPLFESHMNKLKSAIEQAMILSRRSADANQRALAYSRMVDGLNEFRTTICNLYTMPRVPEPVW 419

  Fly   553 LSITTSGSKYSKTVAERFIKELCDLLSFADTKDSNFFISTMLTGILTHHLGWVATVSAFNSSGSK 617
            |:: .||......:...|::||..|:..|   ..|.|:..:||.:||:||.||.||........:
Zfish   420 LTM-MSGPPEKNQLCGHFMRELALLMEQA---SKNQFLPALLTAVLTNHLAWVPTVMPNGQPPIQ 480

  Fly   618 RSESSASAAAIEQRAKLLQVAQKHPYNALWAQLGDLYGAIGMPPKLARTIVCGAEKLWVEKLLNV 682
            ......|:.:::..||      .||||.|||||||||||||.|.:|:||:|.|..:..|::||.:
Zfish   481 IFLEKHSSQSVDMLAK------THPYNPLWAQLGDLYGAIGSPVRLSRTVVVGRRQELVQRLLYL 539

  Fly   683 LTYFIRCSEVRRAAKREDFNKQLI---NDLAAQSQTKNQTGTQE-----RHKSPPTQKRGLSRAA 739
            |||||||||:......|....:.|   ..|...|..:.:....|     .||  |::.
Zfish   540 LTYFIRCSELLETHLLESAEDEAIVMPGSLITTSLRRGEVEESEYVLVTMHK--PSRD------- 595

  Fly   740 TCKQNLNAIADDADDENGELNMYDRDNEDGDPDGLDSGSLDASDGMQTLKKNEIPTVLAFRDSHF 804
                                  |....:..||..        .|..||...:::| |....||.
Zfish   596 ----------------------YLSQGDKSDPAN--------PDEHQTEHTSDVP-VCRVADSP- 628

  Fly   805 VQQELRIGNYLMDTGIDKKMLLARQAQQYFRTGKDGRIRLTVTTPD----NVELCMEEEQSSGTG 865
                      |.||.::.                  .:::..|:|.    :||: .|.:..:|..
Zfish   629 ----------LFDTRLET------------------LVKVGSTSPSERRASVEV-QEAQAEAGGV 664

  Fly   866 SVSTGSVDDGAIEAIDYEDNVEAPPKKNFFWNMVPVAGVK----EGLS-LSDL----AKLQQGIR 921
            .:......|..:|        :.||.|: |.::.|.|.|.    :.:| .|||    .|::|.||
Zfish   665 PIRIHHPSDSLLE--------KKPPDKS-FPDIEPSAKVTFLIGDSMSPESDLESRQQKVEQEIR 720

  Fly   922 IINRKLERRSSSYSVEG--NPDQQQSKTGE--TG-------------VGDFEP-LSHERRASHLS 968
            ...:||.|.:...:.|.  ..||.:||:.|  ||             |..||. .|.:.....|:
Zfish   721 RHKQKLLRDAQQTNTENKLQVDQIKSKSREFVTGRTPRWSASAQEDCVDMFEEYFSEDNPVQTLT 785

  Fly   969 LSDLITQNS-MGKSDRMTWGIEPIKENVSLEEQIHFDHCHKLIEREHGICRQ-TSADNGNGVVFV 1031
            :.|:..::: ..|||            |.||       |   :..:.|.|:. :|||...|:
Zfish   786 IDDVYGKHAPKDKSD------------VQLE-------C---VRVDAGCCKSCSSADLDKGI--- 825

  Fly  1032 LGDNEPLINLKKSSEDLSGDQDSKPTLMLCAQHQRTHDRSKHSGMKFNFEQYPQIATNYMKNKNL 1096
                                                                             
Zfish   826 ----------------------------------------------------------------- 825

  Fly  1097 LMSNYDLLMDKVTKLEASEAAAL------KGSDSTATLAASSSSTAALLPPTTPVTANSDRCVVC 1155
                 ::.:...:.:|..:||.|      :...|.:.|..|.|..|.   |..|
Zfish   826 -----EISLSVPSAVEQKKAAPLNDWEIPRNESSDSALGDSESEDAG---PDLP----------- 871

  Fly  1156 SSGVGINTSATWNQTPSNATELEFETDEMHCYNQSGNGNGFSSKALQSVNSAASIDTLKSSVAVE 1220
                        ...|..|.:.:|: ||
Zfish   872 ------------RADPDGAFDSDFQ-DE------------------------------------- 886

  Fly  1221 PPTPTIPTQMQTTYMRKQQPKRVPSGRSSVSSVAAKCAAVNVSQQLLKLPVPGIKELPQDDESP- 1284
                                                          |:||:||.| |.::...|
Zfish   887 ----------------------------------------------LELPLPGAK-LVENYSKPS 904

  Fly  1285 ----GDQLRAGFIPSLLLSVSDHYVSDMVLQGTCAPPN--KWEMHLREDLALAARSASLISQPAE 1343
                |..|..|:.||        ||.|.||||.   ||  |.:.:|..|||.|.:...|....||
Zfish   905 IANFGRSLFGGYCPS--------YVPDFVLQGV---PNDEKLKQNLVSDLAHAVQHPVLDEPIAE 958

  Fly  1344 NIAIVADMDKWDVRLISSQTQQFPYAGGQSSPVGMSQLVSSMLE-TVQAMNAGGIPAYECLSFLE 1407
            .:.|:||.:||.|.:.|||.:.....|.:   |.:|.|||.:|: |:|.......|.: |:..||
Zfish   959 AVCIIADTEKWTVTVASSQRRSSEKLGKE---VLVSSLVSGLLQSTLQLYRLNLSPNF-CIMHLE 1019

  Fly  1408 SKLQEIYLQSETLAAFLLETDPCRLSDITNPLQLSENDVPLLLSIAYIHTPKISR 1462
            .:|||:|.:|:.||.:|.......:.::...|.:..||:|||.:||..|:|.:::
Zfish  1020 DRLQELYFKSKMLAEYLRGQTRVHVKELGMVLGIESNDLPLLAAIASTHSPHVAQ 1074

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3764	NP_001261977.1	FNIP_N	101..226	CDD:464228	38/141 (27%)
		FNIP_M	461..692	CDD:434087	81/241 (34%)
		FNIP_C	1269..1461	CDD:464229	70/199 (35%)
fnip1	NP_001120937.2	FNIP_N	40..159	CDD:464228	38/141 (27%)
		FNIP_M	317..549	CDD:434087	83/246 (34%)
		FNIP_C	889..1073	CDD:464229	70/199 (35%)