Protein Alignment CG3764 and fnip-2

DIOPT Version :9

• Sequence 1: NP_001261977.1
• Gene: CG3764 / 39902
• FlyBaseID: FBgn0036684
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: NP_001023357.2
• Gene: fnip-2 / 177012
• WormBaseID: WBGene00020208
• Length: 955
• Species: Caenorhabditis elegans
• Alignment Length: 1157
• Identity: 228/1157 - (19%)
• Similarity: 398/1157 - (34%)
• Gaps: 348/1157 - (30%)

  Fly     8 FFPSATPTTPANLAAAPTLTAASAAAAALINSQTTTATTGTATSATTTTLPA------------- 59
            |.|||.|:|    :.:|...:.|.:...:|.:.|::::|.......:.:.|.
 Worm    41 FGPSAAPST----SLSPPFLSPSYSMDYIIEAMTSSSSTSPVPPPVSASRPVAPVVARVEGLRAV 101

  Fly    60 ----RTAHASAG--------VAATASAGNSSSSAKATKQTSRNY---------LSRFPFEGSQVR 103
                |..|:|.|        :.|.....|.:...|..:.|...|         ..|.||..|.
 Worm   102 PVGHRRQHSSPGHLQQFQQELHARHHHANITRLNKKRRNTDTGYDPEARPPKFKHRSPFYQSS-- 164

  Fly   104 VLLYKEDDTRRLLFDSNALQKVMHKDQSATSASISSTSTSGGGKFLKNEKYTSLQNGKIPSKSHS 168
             ...|..|.|.||.:             |.|..:..|:|                  .||:::.:
 Worm   165 -CCLKPTDLRMLLIE-------------AESRVLYDTAT------------------VIPTRNGT 197

  Fly   169 SNGSNFIEVCAEYGYKHNRPSGADITPVGEMVFGSLPMSFCGTALKVHWLPEPSRILCSQVYLTP 233
            ...::.|..|.|:.:...|   .|...:.:|:||::|......:.::|.|.:...||.|:.:..|
 Worm   198 HQNASSISACGEFQFLRKR---KDTRKLSQMIFGAVPNLKTNESFRIHVLEDEETILVSKTFAIP 259

  Fly   234 TSNGGSGHSPYSTL-----------STNSLATPRTSICSEHGSMDG----LSMNSFSMPFSVSVG 283
            ....|:..:..:.:           |::|.:|.:        |:||    .|.:..:.|.:.|..
 Worm   260 KYRKGALPAAAAAVVRNEALMDSSDSSDSQSTVK--------SLDGWRTRTSRSIMTTPEAFSRV 316

  Fly   284 RQMSLTPPLDVPATPADQQSLSIHSIDSSGPRYSSTYSTATDSGYSASGSGSAAGGDQWSYQYSS 348
            |.:|:        |..:||    |.||             ||......||.            ||
 Worm   317 RHISI--------TFGEQQ----HDID-------------TDHSNQHFGSP------------SS 344

  Fly   349 TRSSLGSVLSDQSDAMRKLSMDLACYTGSPYLDGFASDGCL--QRRISRNLRTSFENEHSKNDFI 411
            ..|||....|......:.....||..|.......|.....|  :.|:|....|..::||
 Worm   345 LHSSLPRAFSPPHKISKARRRQLAVTTSLSETSAFPIPSSLKARSRMSSMSSTQADDEH------ 403

  Fly   412 GFLSDNYALNGPVVAPAGGGAGGGSEGGGMAPPQYRRASYCANETRSNPEMGRRQANLRRRAKLG 476
                       |:                                           :::....:.
 Worm   404 -----------PI-------------------------------------------SMQNMRNIA 414

  Fly   477 LAVCISMSESFEEEMELFCSEHIALLESMLSRLRASTELAYINHKNFLQIMFQAWQDTQQWFSDL 541
            |.:.:.:.:.|      |..:||.|:|:.:||..:....|.::...|||.:.::|::..:....|
 Worm   415 LGILVPIKQRF------FLMQHIPLIEAEMSRFESRVVTAALHPSTFLQNISKSWEELTETVCQL 473

  Fly   542 FTAPRIKTPVWLSITTSGSKYSKTVAERFIKELCDLLSFADTKDSNFFISTMLTGILTHHLGWVA 606
            ..|||::.|.||::........:|:|..|.::|..|:...|.|::.:|:|.::|.:|.||:.|||
 Worm   474 HNAPRLRHPYWLALNEKCHLDGRTLATEFCEQLAYLVRRYDRKEAGYFLSNLVTALLMHHMSWVA 538

  Fly   607 TVSAFNSSGSKRSESSASAAAIEQRAKLLQVAQKHP---YNALWAQLGDLYGAIGMPPKLARTIV 668
            :|:      |....::.|...|::.:....::...|   ||||.||..::.||.| ..:.|:..|
 Worm   539 SVA------SPPLHNADSKDQIDENSLFGMMSSGAPTVGYNALMAQYLEISGACG-NMRSAKICV 596

  Fly   669 CGAEKLWVEKLLNVLTYFIRCSEVRRAAKREDFNKQLINDLAAQSQTKNQTGTQERHKSPPT--- 730
            .|.:...:..:.:||::|||||.|          :.:.||...:..|:......:...||.|
 Worm   597 VGEDLEVLASVCSVLSFFIRCSAV----------QHVDNDKMWEVPTEQPFSPCDVSNSPSTSCA 651

  Fly   731 ----QKRGLSRAATCKQNLNAIADDADDENGELNMYDRDNEDGDPDGLDSGS-----LDASDGM- 785
                |::.|.......:..:::|         :....|:|...|.....|.|     |||...|
 Worm   652 HQHQQQQQLKNGYQHPEETSSVA---------MMRRLRNNNQMDTSSTPSTSTAAALLDADVEMV 707

  Fly   786 -QTLKKNEIPTVLAFRDSHFVQQELRIGNYLMDTGIDKKMLLARQAQQYFRTGKDGRIRLTV--- 846
             ||..:....|....|..|.        ::|....||                     ||..
 Worm   708 VQTTTEITSTTTTTPRHHHL--------HHLHSVTID---------------------RLDFPCC 743

  Fly   847 -TTPDNVELCM-EEEQSSGTGSVSTGSVDDGAIEAIDYEDNVEAPPKKNFFWNMVPVAGVKEGLS 909
             |..|:.::.: :...|.|.|.                  ::.|.|..|:..:.|..|..|...:
 Worm   744 PTIADDADMWVPQRPNSEGLGR------------------SMFAGPLNNYCSHFVLSAVQKTDTN 790

  Fly   910 LSDL-AKLQQGIRIINRKLERRSSSYSVEGNPDQQQSKTGETG--------VGDFEPLSHERRAS 965
            :.:: :::...:|..:....|     |....|.|..|...:..        :.|.|
 Worm   791 MPEVYSRMFDEVRCTDFPCHR-----SATATPSQSTSSMCDPAMNPENVLIIADIE--------- 841

  Fly   966 HLSLSDLITQNSMGKSDRMTWGIEPIKENVSLEEQIHFDHCHKLI----EREHGICRQTSADNGN 1026
            .|::..|.|:.    ||.:|   .|.:..|::.||  |...|..:    |...||...:.|
 Worm   842 QLTVKVLSTEG----SDEVT---SPSESIVAMLEQ--FVGIHNAVPANAEFLVGIIEDSLA---- 893

  Fly  1027 GVVFVLGDNEPLINLKKSSEDLSGDQDSKP-TLMLCAQHQRTHDRSKHSGMK 1077
               .::|.:..|:.|.:|      ||...| :|.|.....||.....||.::
 Worm   894 ---HIVGKSLTLVELVRS------DQTKNPNSLQLTPDRVRTIIGCDHSDLR 936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3764	NP_001261977.1	FNIP_N	101..222	CDD:291310	22/120 (18%)
		FNIP_M	461..692	CDD:291311	61/233 (26%)
		FNIP_C	1269..1460	CDD:291312
fnip-2	NP_001023357.2	FNIP_M	399..620	CDD:291311	64/293 (22%)
		FNIP_C	738..950	CDD:291312	49/253 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161294
Domainoid	1	1.000	103	1.000	Domainoid score	I4268
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I3098
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303571at2759
OrthoFinder	1	1.000	-	-		FOG0002940
OrthoInspector	1	1.000	-	-		oto20523
orthoMCL	1	0.900	-	-		OOG6_104859
Panther	1	1.100	-	-	LDO	PTHR21634
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5679
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.020