Protein Alignment CG3764 and fnip2

DIOPT Version :10

• Sequence 1: NP_001261977.1
• Gene: CG3764 / 39902
• FlyBaseID: FBgn0036684
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_004911215.2
• Gene: fnip2 / 100493386
• XenbaseID: XB-GENE-6035566
• Length: 1128
• Species: Xenopus tropicalis
• Alignment Length: 1468
• Identity: 329/1468 - (22%)
• Similarity: 550/1468 - (37%)
• Gaps: 470/1468 - (32%)

  Fly    82 KATKQTSRN-----YLSR-FP---FEGSQVRVLLYKEDDT--RRLLFDSNALQKVMHKDQSATS- 134
            |..:|.|.:     |:|: :|   |:.:.:|:::|::.:.  |::||||.|::::.::.....|
 Frog    41 KRVRQCSSDTGPDLYISQSWPCTDFDLNCIRLIVYQDCERRGRQVLFDSKAVREIRNESTQRASE 105

  Fly   135 ---ASISSTS--TSGGGKFLKNEKYTSLQNGKIPSKSHSSNGSNFIEVCAEYGYKHNRPSGADIT 194
               |.||:.|  ||..|            ...|.|:| :||||......:...|::.:|: :|:.
 Frog   106 DAPAKISTKSCQTSSSG------------TCTISSRS-TSNGSTHTTKDSLPRYQYIKPA-SDVN 156

  Fly   195 PVGEMVFGSLPMSFCGTALKVHWLPEPSRILCSQVYLTPTSNGGSGHSPYSTLSTNSLATPRTSI 259
            .:|||:|||:.||:.|:.||:|::..|.:::.|:|:   ::..||     .:.|||:|.....:|
 Frog   157 MLGEMMFGSVAMSYKGSTLKIHYIRCPPQLMISKVF---SAKVGS-----LSGSTNTLQDSFENI 213

  Fly   260 CSEHGSMD-GLSMNSFSMPFSVSVGRQMSLTPPLDVPATPADQQSLSIHSIDSSGPRYSSTYSTA 323
            ..:.|... |.:.|...   ||.....:.:.........||..::..:..|.|:.  :.:.:||.
 Frog   214 NQDGGGAKLGANQNGQG---SVQNNSNLGVLQMCGSKLLPAMFEARPLRLIRSAS--FFAAHSTP 273

  Fly   324 TD---SGYSA-SGSGSAAGGDQWSYQYSSTRSSLGSVLSDQSDAMRKLSMDLACYTGSPYLDGFA 384
            .|   .|:|. ..||.|..            :||.|:|.....:           .||.|...:|
 Frog   274 VDMPSRGHSEDKDSGIARS------------ASLSSLLITPLPS-----------PGSSYSSNYA 315

  Fly   385 SDGCLQRRISRNLRTSFENEHSKNDFIGFLSDNYALNGPVVAPAGGGAGGGSEGGGMAPPQYRRA 449
            |.  .|||..|:..||.||                                    |:.|......
 Frog   316 SS--YQRRWLRSQTTSLEN------------------------------------GVIPRWSAEE 342

  Fly   450 SY-CANET-RSNP-EMGRRQANLRRRAKLGLAVCISMSE------SFEEEMELFCSEHIALLESM 505
            |: .::|| .||| .:||:        |:.:::..|:.|      ||::    |...|..|.||.
 Frog   343 SFSMSDETYTSNPATVGRK--------KIAVSIIFSLPEQEDSHSSFQD----FFFSHFPLFESH 395

  Fly   506 LSRLRASTELAYINHKN----------FLQIMFQAWQDTQQWFSDLFTAPRIKTPVWLSITTSGS 560
            :::|:::.|.|.|:.:.          :|..:.:|....::...:|::.||:..||||::.:|.|
 Frog   396 MNKLKSAIEKAMISCRKITESSQRVQFYLSRVMEALGHFRETIWNLYSVPRVAEPVWLTMVSSSS 460

  Fly   561 KYSKTVAERFIKELCDLLSFADTKDSNFFISTMLTGILTHHLGWVATV-----SAFNSSGSKRSE 620
            :.|. :.::|:||...|   ::..:.|.|.:.::|.:||:||.||.||     ....|...|.:.
 Frog   461 EKSH-LCQQFLKEFAYL---SEQLNKNQFFAALITAVLTYHLAWVPTVMPNGHPPIKSFSEKHTS 521

  Fly   621 SSASAAAIEQRAKLLQVAQKHPYNALWAQLGDLYGAIGMPPKLARTIVCGAEKLWVEKLLNVLTY 685
            .|.|.           :|:.||||.|||||||||||||.|.::.||:|.|..|..|.::|.||||
 Frog   522 QSVSL-----------LAKSHPYNPLWAQLGDLYGAIGSPVRMTRTVVVGKRKDLVHRILYVLTY 575

  Fly   686 FIRCSEVRRAAKREDFNKQLINDLAAQSQTKNQTGTQERHKSPPTQKRGLSRAATCKQNLNAIAD 750
            ||||||:                             ||.|.
 Frog   576 FIRCSEL-----------------------------QENHL------------------------ 587

  Fly   751 DADDENGELNMYDRDNEDGDPDGLDSGSLDASDGMQTLKKNEIPTVLAFRDSHFVQQELRIGNYL 815
                      ::.|...||:.      .::.|....:|:|.|:      .||.:|
 Frog   588 ----------VHSRVLRDGEQ------IINGSQMTTSLEKGEV------EDSEYV---------- 620

  Fly   816 MDTGIDKKMLLARQAQQYFRTGKDGRIRLTVTTPDNVELCMEEEQSSGTGSVSTGSVDDGAIEAI 880
                                          :.|.:|....:.....|.||:.|
 Frog   621 ------------------------------IVTVNNEPALVPPSLPSNTGATS------------ 643

  Fly   881 DYEDNVEAPPKKNFFWNMVPVA-GVKEGLSLSDLAKLQQGIRIINRKLERRSSSYSVEGNPDQQQ 944
                             :.|.. ||...|..|||...||         |:.||...:..|  ..|
 Frog   644 -----------------LKPEGMGVDSSLRNSDLCFSQQ---------EKSSSHAFLCAN--DNQ 680

  Fly   945 SKTGETGVGDFEPLSHERRASHLSLSDLITQNSMGKSDRMTWGIEPIKENVSLEEQIHFDHCHKL 1009
            |..|..|.....|         :.:.|...:|.:..:.......|.:.::..:...:......|.
 Frog   681 SMHGSYGSCKEHP---------VYVQDPKLENLIPVTRTAACSAESLMKSEYISSPVAMSKWSKT 736

  Fly  1010 IEREHGICRQTSADNGNGVVFVLGDNEPLINLKKSSEDLSGDQDSKPTLMLCAQHQRTHDRSKHS 1074
            ....:.:..::|.|.   |.||:|.:                  ..|.|..|           ..
 Frog   737 GPHTNNMNNESSIDK---VTFVVGCS------------------PSPDLESC-----------RK 769

  Fly  1075 GMK--FNFEQYPQIATNYMKNKNLLMSNYDLLMDKVTKLEASEAAALKGSDSTATLAASSSSTAA 1137
            |:|  .|..|.|...                  |...|:|..:.
 Frog   770 GLKEVVNQNQGPPCD------------------DSKEKVETVDT--------------------- 795

  Fly  1138 LLPPTTP---VTANSDRCVVCSSGVGINTSATWNQTPSNATELEFETDEMHCYNQSGNGNGFSSK 1199
              |.|||   :.:....|..|||        .:::..:....:|..|.|:...:|.     .|:|
 Frog   796 --PVTTPKKNIYSRIPSCDGCSS--------MFDEYFAEGNSIETNTVEVLPSHQF-----LSNK 845

  Fly  1200 ALQS--VNSAASIDTLKSSVAVEPP-----------TPTIPTQMQTTYMRKQQPK-----RVPSG 1246
            .|.|  |.....|.|:.:.....||           :.|:|:|......:::..:     .:|..
 Frog   846 FLPSVPVTEGKQIFTIDTRTCSNPPKHTANAGPDPYSLTLPSQGHPGEAQRESSEVRAEGDIPRN 910

  Fly  1247 RSSVSSVA------AKCAAVNVSQQLLKLPVPGIKELPQDD--ESP-----GDQLRAGFIPSLLL 1298
            .|..|::.      ..|.|.:......::.:|    ||:.|  .||     |..|.||:.|:
 Frog   911 ESCDSALGNSDDEFVTCNAPSDYHTHSEVELP----LPRSDIISSPSLKNFGRSLFAGYCPT--- 968

  Fly  1299 SVSDHYVSDMVLQGTCAPPNKWEMHLREDLALAARSASLISQPAENIAIVADMDKWDVRLISSQT 1363
                 |:.||||.| .:...|.:..|...||.|.....|....||.|.|:||.|:|.|::.|||.
 Frog   969 -----YMPDMVLHG-MSSDEKLKQCLPAGLAHATHHPVLDEPIAEAICIIADTDRWSVQVASSQK 1027

  Fly  1364 QQFPYAGGQSSPVG----MSQLVSSMLETVQAMNAGGIPAYECLSFLESKLQEIYLQSETLAAFL 1424
            :..     .|..:|    :|..||::|:::..:.....|:..|:..||.||||:||:|:.|:.:|
 Frog  1028 KSL-----DSMKLGTDILVSSQVSNLLQSILQLYKLKTPSLFCVMHLEDKLQEMYLKSKMLSEYL 1087

  Fly  1425 LETDPCRLSDITNPLQLSENDVPLLLSIAYIHTPKISR 1462
            .......:.::...|.:..:|:|||.::|..|:|.:::
 Frog  1088 RGHTRVHMKELGIVLGIDSSDLPLLAAVASTHSPHVAQ 1125

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3764	NP_001261977.1	FNIP_N	101..226	CDD:464228	39/132 (30%)
		FNIP_M	461..692	CDD:434087	82/251 (33%)
		FNIP_C	1269..1461	CDD:464229	62/202 (31%)
fnip2	XP_004911215.2	FNIP_N	70..188	CDD:464228	39/131 (30%)
		FNIP_M	353..582	CDD:434087	85/255 (33%)
		FNIP_C	941..1124	CDD:464229	62/200 (31%)