Protein Alignment CG3764 and Fnip1

DIOPT Version :10

• Sequence 1: NP_001261977.1
• Gene: CG3764 / 39902
• FlyBaseID: FBgn0036684
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: NP_001258092.2
• Gene: Fnip1 / 100362347
• RGDID: 2318339
• Length: 1165
• Species: Rattus norvegicus
• Alignment Length: 1470
• Identity: 321/1470 - (21%)
• Similarity: 551/1470 - (37%)
• Gaps: 448/1470 - (30%)

  Fly    97 FEGSQVRVLLYKEDDT--RRLLFDSNALQKVMHKDQSATSASISSTSTSGGGKFLK----NEKYT 155
            |:.||:|:::|::.:.  |.:||||:..:|   .:.::.|...:.......||..:    .:..:
  Rat    37 FDPSQIRLIVYQDCERRGRNVLFDSSVKRK---NEDTSVSKLCNDAQVKVFGKCCQLKPGGDSSS 98

  Fly   156 SLQNGKIPSKSHSSNGSNFIEVCAEYGYKHNRPSGADITPVGEMVFGSLPMSFCGTALKVHWLPE 220
            ||.:    |.:.||:|.   :.|.:  |:.:|.| :|...:|||:|||:.||:.|:.||:|.:..
  Rat    99 SLDS----SITLSSDGK---DQCPK--YQGSRCS-SDANMLGEMMFGSVAMSYKGSTLKIHQIRS 153

  Fly   221 PSRILCSQVYLTPTSNG--GSGHSPYSTL-----STNSLATPRTSICSEHGSMDGLSMNSFSMPF 278
            |.:::.|:|:...|.:.  ||.::...:|     .:|:|....:::.  :|.:..:.::.|..|
  Rat   154 PPQLMLSKVFTARTGSSICGSLNTLQDSLEFINQDSNTLKADSSTVI--NGLLGNIGLSQFCSP- 215

  Fly   279 SVSVGRQMSLTPPLDVPATPADQQSLSIHS--IDSSGPRYSSTYSTATDSGYSASGSGSAAGGDQ 341
                .|..|...||.:..:.:   ..::||  :|..|...|..    .|||.:.|
  Rat   216 ----RRAFSEQGPLRLIRSAS---FFAVHSNPMDMPGRELSED----RDSGIARS---------- 259

  Fly   342 WSYQYSSTRSSLGSVL-----SDQSDAMRKLSMDLACYTGSPYLDGFASDGCLQRRISRNLRTSF 401
                     :||.|:|     |..|      |:..:|  .|.|          |||..|:..||.
  Rat   260 ---------ASLSSLLITPFPSPNS------SLTRSC--ASSY----------QRRWRRSQTTSL 297

  Fly   402 ENEHSKNDFIGFLSDNYALNGPVVAPAGGGAGGGSEGGGMAPPQYRRASYCANETRSNPEMGRRQ 466
            ||                                    |:.|......|:..::....|..|
  Rat   298 EN------------------------------------GVFPRWSIEESFNLSDESCGPNPG--- 323

  Fly   467 ANLRRRAKLGLAVCISMSESFEEEMEL--FCSEHIALLESMLSRLRASTE--------------- 514
              :.|:.|:.:.|..|:|:..:|..:.  |...|..|.||.:::|:::.|
  Rat   324 --IVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADAGQR 386

  Fly   515 -LAYINHKNFLQIMFQAWQDTQQWFSDLFTAPRIKTPVWLSITTSGSKYSKTVAERFIKELCDLL 578
             |||       ..:..|..:.:....:|:|.|||..||||:: .||:.....:..||:||...|:
  Rat   387 SLAY-------NRIVDALTEFRTTICNLYTMPRIGEPVWLTM-MSGTPEKNQLCHRFMKEFTFLM 443

  Fly   579 SFADTKDSNFFISTMLTGILTHHLGWVATVSAFNSSGSK---RSESSASAAAIEQRAKLLQVAQK 640
               :....|.|:..::|.:||:||.||.||........|   ...||.|..         .:|:.
  Rat   444 ---ENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVG---------MLAKT 496

  Fly   641 HPYNALWAQLGDLYGAIGMPPKLARTIVCGAEKLWVEKLLNVLTYFIRCSEVRRAAKREDFNKQL 705
            ||||.|||||||||||||.|.:||||:|.|..:..|::||..|||||||||:
  Rat   497 HPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDLVQRLLYFLTYFIRCSEL------------- 548

  Fly   706 INDLAAQSQTKNQTGTQERHKSPPTQKRGLSRAATCKQNLNAIADDADDENGELNMYDRDNEDGD 770
                            ||.|..                           ||||           |
  Rat   549 ----------------QETHLL---------------------------ENGE-----------D 559

  Fly   771 PDGLDSGSLDASDGMQTLKKNEIPTVLAFRDSHFVQQELRIGNYLMDTGIDKKMLLARQAQQYFR 835
            ...:..|::..:    ||:|.|:      .:|.:|         |:....:|..||.:::::
  Rat   560 EAIVMPGTVITT----TLEKGEV------EESEYV---------LITVHRNKSSLLFKESEE--- 602

  Fly   836 TGKDGRIRLTVTTPDNVELCMEEEQSSGTGSVS---TGSVDDGAIEAIDYEDNVEAPPKKNFFWN 897
                     |.|:..|.:.|........|.:||   ...:.|.:.|.:...|..:
  Rat   603 ---------TGTSNCNCKYCSHPLLGQNTENVSQLEREDIQDNSKELLGISDECQ---------- 648

  Fly   898 MVPVAGVKEGLSLSDLAKLQQGIRIINRKLERRSSSYSVEGNPDQQQSKTGETGVGDFEPLSHER 962
            .:|....:|. :.:|:.:.:..:|   .:|:.:..:....|:....:....|||:   ||.....
  Rat   649 KIPPPDCQEE-NATDVQRYRDKLR---ARLDTKLETIVCTGSAPADKCVLSETGL---EPTEESW 706

  Fly   963 RASHLSLSDLITQNSMGKSDRMTWGIEPIKENVSLEEQIHFDHCHKLIEREHGICRQTSADNGNG 1027
            ::..|..||    |..|.:.|.| ||...|:.........|.            |..|...
  Rat   707 QSKELLDSD----NQTGTAMRPT-GIVVEKKPPDKTVPSAFS------------CELTQTK---- 750

  Fly  1028 VVFVLGDNEPLINLKKSSEDLSGDQDSK-PTLMLCAQHQRTHDRSKHSGMKFNFEQYPQIATNYM 1091
            |.|::||:            :|.|.|:: .:..:..|..|.|.:.        .::...:...:.
  Rat   751 VTFLIGDS------------MSPDSDTELRSQAVVDQINRHHSKP--------LKEDRGVTEKHQ 795

  Fly  1092 KNKNLLMSNYDLLMDKVTKLEASEAAALKGSDSTATLAASSSSTAALLPPTTPVTANSDRCVVCS 1156
            :|             |:||.::       |...|..:.:..|..   ||              |
  Rat   796 EN-------------KITKDQS-------GGSGTHNMVSGESCE---LP--------------C- 822

  Fly  1157 SGVGINTSATWNQTPSNATELEFETDEMHCYNQSGNGNGFSSKALQSVNSAASIDTLKSSVAVEP 1221
                      |:.:         :.:.|..:::..|.:...::.:..|....|.|:.:....:|.
  Rat   823 ----------WSHS---------DPESMSLFDEYFNDDSIETRTIDDVPVKTSTDSKEYCCMLEY 868

  Fly  1222 P--------------------------TPTIPTQMQTTYM--------RKQQPKR--------VP 1244
            |                          ....|.|.|...:        ::...|:        :|
  Rat   869 PKRLYTKDNKQQNELCKCIETVHQDSCNACFPQQDQRDALSILVPHGDKESSDKKIAVGTEWDIP 933

  Fly  1245 SGRSSVSSVA---AKCAAVNVSQQL--------------LKLPVPGIKELPQDDESPGDQLRAGF 1292
            ...||.|::.   ::....::.:|:              .::|.||.|.:......|.   .|.|
  Rat   934 RNESSDSALGDSESEDTGPDIRRQVGSYCGGDQEDWAEEDEIPFPGSKLIEVSAVQPN---IANF 995

  Fly  1293 IPSLLLSVSDHYVSDMVLQGTCAPPNKWEMHLREDLALAARSASLISQPAENIAIVADMDKWDVR 1357
            ..|||......||.|.|||| .....:....|..||:.|.:...|....||.:.|:||||||.|:
  Rat   996 GRSLLGGYCSSYVPDFVLQG-IGSDERLRQCLASDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQ 1059

  Fly  1358 LISSQTQQFPYAGGQSSPVGMSQLVSSMLETVQAMNAGGIPAYECLSFLESKLQEIYLQSETLAA 1422
            :.|||.:......|:.  |.:|.|||::|.:...:....:....|:..||.:|||:|.:|:.||.
  Rat  1060 VASSQRRVTDNKLGKE--VLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLAE 1122

  Fly  1423 FLLETDPCRLSDITNPLQLSENDVPLLLSIAYIHTPKISR 1462
            :|.......:.::...|.:..:|:|||.::|..|:|.:::
  Rat  1123 YLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQ 1162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3764	NP_001261977.1	FNIP_N	101..226	CDD:464228	36/130 (28%)
		FNIP_M	461..692	CDD:434087	85/251 (34%)
		FNIP_C	1269..1461	CDD:464229	61/191 (32%)
Fnip1	NP_001258092.2	FNIP_N	41..159	CDD:464228	36/130 (28%)
		FNIP_M	316..548	CDD:434087	86/256 (34%)
		FNIP_C	975..1161	CDD:464229	61/191 (32%)