Protein Alignment Exn and arhgef3l

DIOPT Version :9

• Sequence 1: NP_001097630.2
• Gene: Exn / 39900
• FlyBaseID: FBgn0261547
• Length: 2029
• Species: Drosophila melanogaster
• Sequence 2: XP_005162130.1
• Gene: arhgef3l / 553761
• ZFINID: ZDB-GENE-050522-85
• Length: 532
• Species: Danio rerio
• Alignment Length: 496
• Identity: 108/496 - (21%)
• Similarity: 193/496 - (38%)
• Gaps: 136/496 - (27%)

  Fly  1521 IGLQAKAKPEPLVKPRPTALQLVE--PKNGPSRTLWSE-IPEVIHSCILPTLTSRERSLQEAKFE 1582
            |..:.:|:|.|   |.|.:.|...  |:...|: |||: :..:.|.     |:::|...||..:|
Zfish   113 ISFRTEARPLP---PMPRSRQKASSFPRRRSSQ-LWSDTVDNMSHE-----LSTKEIKRQEVIYE 168

  Fly  1583 IITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALF---SYIVPVHECSERLLTELEACWQ 1644
            :...|...::.|:|:::.:  :...|...:::..:...:|   ..::|:|   |.||..||.
Zfish   169 LTQGEKQLIEDLSLVKKVY--YEPMLKLDIMTESELGQIFGTLDSLIPLH---EDLLVRLEG--- 225

  Fly  1645 DNIMLLGLSRCIYEIAERH------FHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEAS 1703
                |.|..:.:.|:....      ...|:.:|.:|......|.:.|:.|.   .:|.|...:.|
Zfish   226 ----LRGAEKTVQEVGPTMMDWFPCLEAYITYCCNQVGAKALLDQKKQDKR---VEQFLRLCQES 283

  Fly  1704 PSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRW 1768
            .....|:|.:||.||..|:.:.|||:..: .|.:||:..:.::....:.|:|:::.:.|......
Zfish   284 SFSRKLDLWNFLDLPRSRLVKYPLLLKEI-QKSTPLDHPDEDALPQAMELIQRIITEVNLKTGEA 347

  Fly  1769 EQAF---------ELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAK 1824
            |..|         :.:|:|       .::|              .|||...|||          |
Zfish   348 ECQFYRRGLCYAEDSQRVA-------EIQA--------------SRFLYCHGEL----------K 381

  Fly  1825 LTFGKRLTKISIYAFLFSDLLLLCK-----RRGESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLK 1884
            .|.|::|     :.|||..:|:|.:     |.|...|.|:    |..:..|      .|..:||.
Zfish   382 STKGQKL-----HVFLFELVLVLTRPVAQDREGPVQFQVY----RQPMPAA------HLHLEDLP 431

  Fly  1885 D----QAGKNLILMT---LLENCDR-------KTVELVLSCPSVSDQQRWLQAMR---------- 1925
            |    .:|......|   .::||.|       |:....|......::|:|:..:|
Zfish   432 DGEPSSSGSFRGAFTGNDKVKNCFRVSTTGRSKSQSHSLQANDSFNKQQWISCLRQAMVQSRDRQ 496

  Fly  1926 -------PPEAETPGEKLYESWDCPQVVAKHSYES--DEPD 1957
                   |.|..:|...||.:      :|:.:..|  |.||
Zfish   497 AQSSPCNPNERLSPEPALYNN------IAELTINSDVDMPD 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exn	NP_001097630.2	RhoGEF	1581..1763	CDD:279015	40/190 (21%)
		PH_ephexin	1805..1931	CDD:269929	37/161 (23%)
		SH3_ephexin1_like	1944..1998	CDD:212727	5/16 (31%)
arhgef3l	XP_005162130.1	RhoGEF	165..341	CDD:279015	40/191 (21%)
		PH_RhoGEF3_XPLN	355..489	CDD:269976	38/179 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3601
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030