| Sequence 1: | NP_001097630.2 | Gene: | Exn / 39900 | FlyBaseID: | FBgn0261547 | Length: | 2029 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_005272521.1 | Gene: | ARHGEF18 / 23370 | HGNCID: | 17090 | Length: | 1426 | Species: | Homo sapiens |
| Alignment Length: | 1201 | Identity: | 228/1201 - (18%) |
|---|---|---|---|
| Similarity: | 398/1201 - (33%) | Gaps: | 424/1201 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 962 SCIQ-----------LSSSGSTLTISSD---------------HKTNSLYESSL---AAAGCVVY 997
Fly 998 GSASVGC--RSSLGSSAGSRDSG-KPGDKR--SSIAGSSDNSDAWVDISDGEIGQATTDATANEA 1057
Fly 1058 QFIVVRERFKPHRTRSPDWSKRIRDKRLQQKKAISCIEDDSDHYYETLS------PLGNKRHSTQ 1116
Fly 1117 LVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYND 1181
Fly 1182 SGVDMRNHRL------PKPP-----PP-----------------QNQVYEFVRKF---KDFISSK 1215
Fly 1216 KSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKN 1280
Fly 1281 GKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPE----------IHGSGE 1335
Fly 1336 LDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERE 1400
Fly 1401 LDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGS 1465
Fly 1466 SGVSTGNEAGLGDELS-SEPH--SLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKA 1527
Fly 1528 KPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSL---QEAKFEIITSEAS 1589
Fly 1590 YLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDN-------- 1646
Fly 1647 --IMLLG---LSRCIYEIAERHFHVYVAFCE-HQGRMDRTLRRLKESKESLAFQQHLERLEASPS 1705
Fly 1706 CCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQ 1770
Fly 1771 AFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDA------------ 1823
Fly 1824 -KLTFGKRLTKISIYAFLFSDLLLLCKRRGES-CFSVFDYCP-----------------RSMLTL 1869
Fly 1870 AA---GDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCP-------SVSDQQRWLQAM 1924
Fly 1925 RPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWY---------QG 1980
Fly 1981 ERIRDGAVGWFPGSYT---EELNSAHVRARN 2008 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Exn | NP_001097630.2 | RhoGEF | 1581..1763 | CDD:279015 | 39/195 (20%) |
| PH_ephexin | 1805..1931 | CDD:269929 | 35/166 (21%) | ||
| SH3_ephexin1_like | 1944..1998 | CDD:212727 | 13/65 (20%) | ||
| ARHGEF18 | XP_005272521.1 | RhoGEF | 513..707 | CDD:238091 | 40/199 (20%) |
| PH_ARHGEF18 | 747..865 | CDD:275437 | 27/131 (21%) | ||
| PH | <786..851 | CDD:278594 | 9/72 (13%) | ||
| DUF2570 | 1061..1156 | CDD:305162 | |||
| PKK | 1086..1193 | CDD:289257 | |||
| DUF4200 | 1111..>1190 | CDD:290574 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||