Protein Alignment Ogdh and sucA

DIOPT Version :10

• Sequence 1: NP_730226.3
• Gene: Ogdh / 39899
• FlyBaseID: FBgn0010352
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_415254.1
• Gene: sucA / 945303
• ECOCYCID: EG10979
• Length: 933
• Species: Escherichia coli
• Alignment Length: 1080
• Identity: 405/1080 - (37%)
• Similarity: 554/1080 - (51%)
• Gaps: 190/1080 - (17%)

  Fly    53 FANGSTASYVEEMYNAWLRDPTSVHTSWDAYFRSNSYVSPPNLAPVQANTLPLTAFNFGGAVAGA 117
            :.:|:..|::|::|..:|.||.||..:|.:.|:.   :....:.|.|.::  .|...|......|
E. coli    14 YLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQ---LPGTGVKPDQFHS--QTREYFRRLAKDA 73

  Fly   118 APDSKTIDD------HLAVQAIIRSYQIRGHNIAHLDPLEINTPELPGNSSTKSIYANF-SFGEQ 175
            :..|.||.|      .:.|..:|.:|:.|||..|:||||     .|........:..:| ...|.
E. coli    74 SRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPL-----GLWQQDKVADLDPSFHDLTEA 133

  Fly   176 DMDRQFKLPSTTFIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLN 240
            |....|.:.|  |..|.| ::.|.|:|..|:..||..||.|:|.|.|.|:..||::|.|: |...
E. coli   134 DFQETFNVGS--FASGKE-TMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIES-GRAT 194

  Fly   241 FSPEEKRLILARLTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMP 305
            |:.|||:..|:.||.|.|.|.:|..|:...|||.|||.:.:||.|||:|..:...|...|::||.
E. coli   195 FNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMA 259

  Fly   306 HRGRLNTLANVCRKPLNQIFTQFAGLEAADDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSH 370
            ||||||.|.||..|....:|.:|||......|:||||||:|...:  .:.....:.||:..||||
E. coli   260 HRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSD--FQTDGGLVHLALAFNPSH 322

  Fly   371 LEAVDPVVQGKTRAEQFYRGDQEGKKVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVV 435
            ||.|.|||.|..||......:....||:.|.||||||..|||||.||:::|....|...||:.:|
E. coli   323 LEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIV 387

  Fly   436 ANNQIGFTT-DPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDL 499
            .|||:|||| :|..:||:|||||:.::|.||||||||||||||..|.::|.::|.||.:|..|||
E. coli   388 INNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDL 452

  Fly   500 VGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENICEEAF 564
            |.|||:||||.|||..|||||||||:||.....:|||||..|...|.|:.
E. coli   453 VCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDA--------------- 502

  Fly   565 ALAKTETHVKYKDWLDS----------------PWSGFFEGK-DPLKVAPTGVKEETLIHIGNRF 612
                ||....|:|.||:                .||.:...: |  :..|..|:.:.|..:..|.
E. coli   503 ----TEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWD--EEYPNKVEMKRLQELAKRI 561

  Fly   613 SSPPPNAAEFVIHKGLLRVLAARKAM-VDEKVADWALGEAMAFGSLLKEGIHVRLSGQDVERGTF 676
            |: .|.|.|  :...:.::...|:|| ..||:.||...|.:|:.:|:.|||.|||||:|..||||
E. coli   562 ST-VPEAVE--MQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTF 623

  Fly   677 SHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEYAVLGFEHGYSMTNPNALVLWEAQFG 741
            .|||.|:|:| .:.:||..|||::..|..:.|.:|.|||.|||.||:||:...|..|.:||||||
E. coli   624 FHRHAVIHNQ-SNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFG 687

  Fly   742 DFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSDDPDYFPPES 806
            ||:|.||.:||||||||:.||.|..|||||||||.||.||||||.|:||:||:.::.
E. coli   688 DFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ-------- 744

  Fly   807 DEFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKSPFSEMSEGS 871
                       |..|...||||..||:||||.....|:||::.:||||||||.|.|...|::.|:
E. coli   745 -----------NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT 798

  Fly   872 EFQRIIPDNGPAGQ-NPSNVKKVVFCSGRVYYDLTKTRREKQLEGEIAIVRVEQISPFPFDLVKE 935
                .:|..|...: :|..||:||.|||:|||||.:.|| |..:.::||||:||:.|||...::|
E. coli   799 ----FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRR-KNNQHDVAIVRIEQLYPFPHKAMQE 858

  Fly   936 QANLYKNA-ELVWAQEEHKNQGSWTYVQPRFLTALNHSRDVSQSDEQSSSTNTTTTTDHTNHESD 999
            ....:.:. :.||.|||..|||:|...|       :|.|:|.
E. coli   859 VLQQFAHVKDFVWCQEEPLNQGAWYCSQ-------HHFREVI----------------------- 893

  Fly  1000 TDSDSKSKPWLSRMFAAPNSSTGGDPKDPAQTLGGDFNAAKHFDLKNVRHDFNRPAGIAAAPGAR 1064
                    |:
E. coli   894 --------PF------------------------------------------------------- 895

  Fly  1065 IAKTGRKISYVGRACGASTATGSKAQHIRELNALLNDAIS 1104
                |..:.|.||...||.|.|..:.|.::...|:|||::
E. coli   896 ----GASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALN 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ogdh	NP_730226.3	SucA	53..1102	CDD:440333	403/1076 (37%)
sucA	NP_415254.1	sucA	2..931	CDD:236499	405/1078 (38%)