Protein Alignment Ogdh and Dhtkd1

DIOPT Version :10

• Sequence 1: NP_730226.3
• Gene: Ogdh / 39899
• FlyBaseID: FBgn0010352
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_001020891.1
• Gene: Dhtkd1 / 361272
• RGDID: 1308092
• Length: 920
• Species: Rattus norvegicus
• Alignment Length: 873
• Identity: 351/873 - (40%)
• Similarity: 504/873 - (57%)
• Gaps: 74/873 - (8%)

  Fly   123 TIDDHLAVQAIIRSYQIRGHNIAHLDPLEINTPELPGNSSTKSIYANFSFGEQDMDRQFKLPSTT 187
            ::|..||  .::..|...||..|.::||      .||.:...:: .......|.:...|......
  Rat    51 SVDHGLA--RLVTVYCEHGHKAAQINPL------FPGQALLDTV-PEIQALVQTLQGPFTTTGLL 106

  Fly   188 FIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFSPEEKRLILAR 252
            .:|.:|||  |:|:|..|.::||..|.:|...:.|.|:.:|..:|||......|:.||::.:...
  Rat   107 NMGKEEAS--LEEVLAYLNHIYCGPISIETAQLQSQEEKDWFARRFEELKKETFTTEERKHLSKL 169

  Fly   253 LTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMPHRGRLNTLANVC 317
            |..:..|:.|||.|:::.||:|.||.|.|:....|::.:|...|:..:|:|||||||||.|..:.
  Rat   170 LLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLL 234

  Fly   318 RKPLNQIFTQFAGLEAADD---GSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQ 379
            :.|...:|.:..||....:   ..|||..||.:.:: |:...::.:.:.::.|||||||::||..
  Rat   235 QLPPELMFRKMRGLSEFPENVAAIGDVLSHLTSSVD-LDFGAHRPLHVTMLPNPSHLEAINPVAV 298

  Fly   380 GKTRAEQFYRGD---------QEGKKVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVV 435
            ||||..|..:.|         |.|.||:.:.:||||:|||||:|.||..||:||.:...|:||::
  Rat   299 GKTRGRQQSQEDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLI 363

  Fly   436 ANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDLV 500
            .|||:|:||.....|||.|.:|:.::|...|.|||.|.||.|:...::|.|::..|.||.:|||:
  Rat   364 VNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLL 428

  Fly   501 GYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENICEEAFA 565
            .||:.||||:|||.||.|:||:.||..|:..|.||:.|||.|.:|.|||..:.|.|
  Rat   429 CYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKASY--------- 484

  Fly   566 LAKTETHV----KYK---DWLDSPWSGFFEGKDPLKVAPTGVKEETLIHIGNRFSSPPPNAAEFV 623
            .||...|:    .|.   ..|.:.|.|..:....:....|||..|.|..:|.:....|   .|..
  Rat   485 YAKLNGHLANVAHYSPPAPHLQARWQGLVQPAACVTTWDTGVPLELLRFVGVKSVEVP---EELQ 546

  Fly   624 IHKGLLRVLAARKAMVDEKV-----ADWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVL 683
            :|..||::....:.   |||     .|||..|.:|.||||.:|.:||||||||.|||||.||.::
  Rat   547 LHSHLLKMYVQSRM---EKVKNGTNLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMV 608

  Fly   684 HHQLVDKATYNSLQHMYPDQAPY-SVSNSSLSEYAVLGFEHGYSMTNPNALVLWEAQFGDFSNTA 747
            ..|..|. .|..|.||.|:|..: .||||.|||.||||||:|.|:.:|..|.|||||||||.|.|
  Rat   609 VCQNTDD-VYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGA 672

  Fly   748 QSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSDDPDYFPPESDEFGVR 812
            |.|.|.|||.|::||:.|||||:|||||.:|.||:|||||:||||||.         :|.|.||
  Rat   673 QIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPDHSSCRIERFLQMC---------DSAEEGV- 727

  Fly   813 QLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKSPFSEMSEGSEFQRII 877
            ....:|..|.:.:|||.|:|:||||:...||||||:.:||.|||:|.|.|...||:.|:.|:.:|
  Rat   728 DSDTVNMFVVHPTTPAQYFHLLRRQMMRNFRKPLIVASPKMLLRYPVAVSTLEEMAPGTAFKPVI 792

  Fly   878 PDNGPAGQNPSNVKKVVFCSGRVYYDLTKTRR----EKQLEGEIAIVRVEQISPFPFDLVKEQAN 938
               |.:..:|.|||.::||||:.:|.|.|.|.    :|:   :.||:|:|::.|||.|.::::..
  Rat   793 ---GDSSVDPKNVKTLIFCSGKHFYALLKQRESLGAKKR---DFAIIRLEELCPFPLDSLQQEMG 851

  Fly   939 LYKNA-ELVWAQEEHKNQGSWTYVQPRF 965
            .||:. :::|:|||.:|.|.|::|.|||
  Rat   852 KYKHVQDIIWSQEEPQNMGPWSFVYPRF 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ogdh	NP_730226.3	SucA	53..1102	CDD:440333	351/873 (40%)
Dhtkd1	NP_001020891.1	kgd	58..914	CDD:476867	348/864 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..318		6/18 (33%)