Protein Alignment Nc73EF and Ogdhl

DIOPT Version :9

• Sequence 1: NP_001097629.1
• Gene: Nc73EF / 39899
• FlyBaseID: FBgn0010352
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_001382038.1
• Gene: Ogdhl / 290566
• RGDID: 1310916
• Length: 1010
• Species: Rattus norvegicus
• Alignment Length: 1105
• Identity: 624/1105 - (56%)
• Similarity: 756/1105 - (68%)
• Gaps: 126/1105 - (11%)

  Fly    12 LSPMAHKNFATWLLKSSSSQQMAKVTAAAAVRTYNSAAAEPFANGSTASYVEEMYNAWLRDPTSV 76
            |.|.|.|..||..:.:...::.:........|:         ..|.:.|||||||.|||.:|.||
  Rat    11 LGPQARKLLATRDIAAFGGRRRSSGPPTTIPRS---------RGGVSPSYVEEMYFAWLENPQSV 66

  Fly    77 HTSWDAYFR---SNSYVSPPNLAPVQANTLPLTAFNFGGAVAGAAPDSKTIDDHLAVQAIIRSYQ 138
            |.|||.:|:   ..:.|.|....|      |........:|:.....||.::||||||::||:||
  Rat    67 HKSWDNFFQRATKEASVGPAQPQP------PAVIQESRASVSSCTKTSKLVEDHLAVQSLIRAYQ 125

  Fly   139 IRGHNIAHLDPLEINTPEL----PGN-SSTKSIYANFSFGEQDMDRQFKLPSTTFIGGDEASLPL 198
            ||||::|.||||.|...:|    |.: .:|....|.:...|.|:|::|:||:||||||.|.:|.|
  Rat   126 IRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFRLPTTTFIGGSENTLSL 190

  Fly   199 KEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFSPEEKRLILARLTRATGFEAFL 263
            :||:.|||:.||..||:||||||.:|||.|||::||||||:.||.||||.:||||.|:..||.||
  Rat   191 REIIRRLESTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMKFSIEEKRTLLARLVRSMRFEDFL 255

  Fly   264 AKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMPHRGRLNTLANVCRKPLNQIFTQF 328
            |:|:||||||||||||:||||||.|||.|:|:|||:||:|||||||||.||||.||.|.|||.||
  Rat   256 ARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGVENVILGMPHRGRLNVLANVIRKDLEQIFCQF 320

  Fly   329 -AGLEAADDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDQ 392
             ..|||||:||||||||||.|.||:|||||:||.|::||||||||||||||||||:||||||||.
  Rat   321 DPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDA 385

  Fly   393 EGKKVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCTD 457
            :|:||||||:||||||.||||||||.||||||.|||:||:|||.|||||||||||.:|||||.||
  Rat   386 QGRKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTD 450

  Fly   458 VARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMYQ 522
            ||||||||||||||||||||::||.||||||.||:||.|:|||.|||.||||:|||||||||||:
  Rat   451 VARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYK 515

  Fly   523 KIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENICEEAFALAKTETHVKYKDWLDSPWSGFF 587
            :|.|....|..||||||||||||.:|.:...|||:.|||||:..:|.:..:..|.||||||.|||
  Rat   516 QIHKQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFF 580

  Fly   588 --EGKDPLKVAP-TGVKEETLIHIGNRFSSPPPNAAEFVIHKGLLRVLAARKAMVDEKVADWALG 649
              :|:......| ||:.|:||.||||..||.|  ..:|.||.||.|:|..|..|..::..||||.
  Rat   581 NVDGEPKSMTYPTTGIPEDTLSHIGNVASSVP--LEDFKIHTGLSRILRGRADMTKKRTVDWALA 643

  Fly   650 EAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLS 714
            |.|||||||||||||||||||||||||||||||||.|.||:.|...:.|::||||||:|.|||||
  Rat   644 EYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQDVDRRTCVPMNHLWPDQAPYTVCNSSLS 708

  Fly   715 EYAVLGFEHGYSMTNPNALVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGM 779
            ||.|||||.||:|.:||||||||||||||.||||.|||||||:||:||||.:|:|:|||||||||
  Rat   709 EYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGM 773

  Fly   780 GPEHSSCRVERFLQMSSDDPDYFPPESDEFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRK 844
            ||||||.|.|||||||:||.|.:|..:::|.|.||:|.||||.||||||:|:|:||||:.|||||
  Rat   774 GPEHSSARPERFLQMSNDDSDAYPVFTEDFEVSQLYDCNWIVVNCSTPASYFHVLRRQVLLPFRK 838

  Fly   845 PLILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIPDNGPAGQNPSNVKKVVFCSGRVYYDLTKTRR 909
            |||:.|||||||||:|||.|.:|..|:.|||:||::|||.|:|..|::::||:|:|||||.|.|.
  Rat   839 PLIVFTPKSLLRHPDAKSSFDQMVSGTSFQRMIPEDGPAAQSPERVERLIFCTGKVYYDLVKERS 903

  Fly   910 EKQLEGEIAIVRVEQISPFPFDLVKEQANLYKNAELVWAQEEHKNQGSWTYVQPRFLTALNHSRD 974
            .:.||.::||.|:||||||||||:..:|..|..|||||.||||||.|.:.|:.|||:|.|.|||.
  Rat   904 SQGLEKQVAITRLEQISPFPFDLIMREAEKYSGAELVWCQEEHKNMGYYDYISPRFMTLLGHSRP 968

  Fly   975 VSQSDEQSSSTNTTTTTDHTNHESDTDSDSKSKPWLSRMFAAPNSSTGGDPKDPAQTLGGDFNAA 1039
            :                                 |
  Rat   969 I---------------------------------W------------------------------ 970

  Fly  1040 KHFDLKNVRHDFNRPAGIAAAPGARIAKTGRKISYVGRACGASTATGSKAQHIRELNALLNDAIS 1104
                                              ||||...|:.|||:|..|:..|...|:.|.:
  Rat   971 ----------------------------------YVGREPAAAPATGNKNTHLVSLRKFLDTAFN 1001

  Fly  1105  1104
              Rat  1002  1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nc73EF	NP_001097629.1	2-oxogl_dehyd_N	51..86	CDD:292696	19/37 (51%)
		sucA	53..1104	CDD:236499	617/1062 (58%)
		TPP_E1_OGDC_like	259..521	CDD:238974	212/262 (81%)
		Transket_pyr	645..856	CDD:280874	159/210 (76%)
		OxoGdeHyase_C	863..1102	CDD:293475	75/238 (32%)
Ogdhl	NP_001382038.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..47		1/27 (4%)
		sucA	46..1001	CDD:236499	617/1059 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335666
Domainoid	1	1.000	492	1.000	Domainoid score	I355
eggNOG	1	0.900	-	-		E1_COG0567
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1221	1.000	Inparanoid score	I173
OMA	1	1.010	-	-		QHG62893
OrthoDB	1	1.010	-	-		D134699at2759
OrthoFinder	1	1.000	-	-		FOG0000624
OrthoInspector	1	1.000	-	-		otm45800
orthoMCL	1	0.900	-	-		OOG6_100311
Panther	1	1.100	-	-	LDO	PTHR23152
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X894
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770