Protein Alignment Ogdh and ogdh-2

DIOPT Version :10

• Sequence 1: NP_730226.3
• Gene: Ogdh / 39899
• FlyBaseID: FBgn0010352
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: NP_001256410.1
• Gene: ogdh-2 / 179674
• WormBaseID: WBGene00014098
• Length: 911
• Species: Caenorhabditis elegans
• Alignment Length: 870
• Identity: 336/870 - (38%)
• Similarity: 485/870 - (55%)
• Gaps: 85/870 - (9%)

  Fly   133 IIRSYQIRGHNIAHLDPLEIN--------TPELPGNSSTKSIYANFSFGEQDMDRQFKLPSTTFI 189
            :|.:::..|:..|.||||.:.        .|.:.|.|..:::..|||
 Worm    58 LINAFRRYGYLEADLDPLGLRKVESVAELDPAIYGLSLDENVKGNFS------------------ 104

  Fly   190 GGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFSPEEKRLILARLT 254
                    |.::..:|.::||....:|||.||:.|:..||.:.||.........||...|...:.
 Worm   105 --------LHDLAEQLRHIYCGPTAIEFMHINNWEERQWISQNFENCIAEELRKEELLRIGDLML 161

  Fly   255 RATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMPHRGRLNTLANVCRK 319
            :...|:.||:.|:.:.||:|.||.|.|.....|:.:.:.|..||.:|:|:.||||||.|..:...
 Worm   162 KCENFDKFLSTKFPTLKRYGAEGAESMFAFFSELFEGAAEKQVEEIIIGIAHRGRLNLLTQLMDF 226

  Fly   320 PLNQIFTQFAGL----EAADDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQG 380
            |...:|.:..|.    |:| |.:|||..||.:..:  .:.:..|:.:.::.||||||||:||..|
 Worm   227 PPVHMFRKIKGRAEFPESA-DAAGDVLSHLVSSFD--YKGSEGNVHVTMLPNPSHLEAVNPVAMG 288

  Fly   381 KTRAE--QFYRGD--------QEGKKVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVV 435
            |.||.  ...:||        :.|..|:::|:|||.||.|||||:|::.||..|.:...||:|:|
 Worm   289 KARARAWSMNKGDYSPDERSARAGDSVLNVLVHGDGAFTGQGVVWESIALSQAPHFRLGGTVHLV 353

  Fly   436 ANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDLV 500
            .||||.||.:....|||.:|||:|:....|:.|||.|.||.|:...::|..:|..|.||..|:||
 Worm   354 TNNQIAFTAESSVGRSSTHCTDIAKAFEYPVIHVNGDHPEEVVKATRLALAYRERFRKDVFINLV 418

  Fly   501 GYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKY-ENICEEAF 564
            .:||.||||:|:|.||.|:||:::...::...|:.|:|:.||..|.|.||....|: |.:..|
 Worm   419 CFRRWGHNELDDPTFTSPVMYKEVEARESVPRLFLDRLVEEGFTTEEAVKEQLQKHTEQLNNE-- 481

  Fly   565 ALAKTETHVKYKDWLDSPWSGFFEGKDPLKVAPTGVKEETLIHIGNRFSSPPPNAAEFVIHKGLL 629
             |.|.::.|.........|.||.:....::...|||..:.|..||......|   .:|..||.|.
 Worm   482 -LKKVDSTVPIDISHRGRWEGFKQAPKAIESWDTGVATDLLRFIGAGSVKVP---EDFDTHKHLY 542

  Fly   630 RV---LAARKAMVDEKVADWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQLVDKA 691
            ::   ...:|....|.: |||..|||||||:|.||..||:|||||.||||.|||.:    :||::
 Worm   543 KMHIDSRMQKMQTGEGI-DWATAEAMAFGSILLEGNDVRISGQDVGRGTFCHRHAM----MVDQS 602

  Fly   692 T---YNSLQHMYPDQA-PYSVSNSSLSEYAVLGFEHGYSMTNPNALVLWEAQFGDFSNTAQSIID 752
            |   :..|..:..:|. ...|:|:.|||.|:||||.|:|..||..|.:||||||||.|.||.|||
 Worm   603 TDHIHIPLNELVEEQKNQLEVANNLLSEEAILGFEWGFSSENPRRLCIWEAQFGDFFNGAQIIID 667

  Fly   753 QFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSDDPDYFPPESDEFGVRQLHDI 817
            .|::|.:|||:..|||.||||||.:|.||||||||:|||||:.....|..|.:.:        ::
 Worm   668 TFLASAESKWLTSSGLTMLLPHGFDGAGPEHSSCRMERFLQLCDSREDQTPVDGE--------NV 724

  Fly   818 NWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIPDNGP 882
            |..|||.:|.|.|:|:||||:...:|||||:..||.|||||:|.|..:|...|:.:|.:|.:.
 Worm   725 NMRVANPTTSAQYFHLLRRQVVPNYRKPLIVVGPKILLRHPKAASTINEFGPGTTYQNVISEE-- 787

  Fly   883 AGQNPSNVKKVVFCSGRVYYDLTKTRREKQLEGEIAIVRVEQISPFPFDLVKEQANL--YKNA-E 944
            ...:...:|||:|.||:.:.::.|.|.|:.|:..:||||||.:.|||  :|..||.|  |..| :
 Worm   788 HATSSQKIKKVIFVSGKHWINVEKARDERGLKDSVAIVRVEMLCPFP--VVDLQAVLKKYPGAQD 850

  Fly   945 LVWAQEEHKNQGSWTYVQPRFLTAL 969
            .||:|||.:|.|:|::|:|||..||
 Worm   851 FVWSQEEPRNAGAWSFVRPRFENAL 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ogdh	NP_730226.3	SucA	53..1102	CDD:440333	336/870 (39%)
ogdh-2	NP_001256410.1	SucA	45..911	CDD:440333	336/870 (39%)