Protein Alignment Ogdh and dhtkd1

DIOPT Version :10

• Sequence 1: NP_730226.3
• Gene: Ogdh / 39899
• FlyBaseID: FBgn0010352
• Length: 1105
• Species: Drosophila melanogaster
• Sequence 2: XP_031754904.1
• Gene: dhtkd1 / 100493977
• XenbaseID: XB-GENE-980611
• Length: 967
• Species: Xenopus tropicalis
• Alignment Length: 950
• Identity: 359/950 - (37%)
• Similarity: 525/950 - (55%)
• Gaps: 106/950 - (11%)

  Fly    74 TSVHTSWDAYFRSNSYVSPPN---LAPVQANTLPLTAFNFGGA-------------VAGAAPDSK 122
            ||:..|.|...|::..:|..|   |.||..    :|:.:.|.|             |...||...
 Frog    26 TSIFYSKDRENRAHRDISLQNCSVLDPVSG----VTSSDEGTAMRRPSRWHREDPPVQCTAPPDP 86

  Fly   123 T------------IDDHLAVQAIIRSYQIRGHNIAHLDPLEIN------TPELPGNSSTKSIYAN 169
            |            :|..||  .::.:|:..||..|.::||...      .||:  ...|:.::..
 Frog    87 TNRRLWEGASFVNLDHGLA--RLVTAYREHGHKAAKINPLFTGQAVMDMVPEI--QELTEILHGP 147

  Fly   170 FSFGEQDMDRQFKLPSTTFIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFE 234
            |.             :|..:...::...::|:|..|::.||.:|.||...:.:.::..|..:|||
 Frog   148 FI-------------TTGLLNMGKSEATIEEVLAYLDHTYCGQISVETSQLQNFKEREWFSRRFE 199

  Fly   235 TPGVLNFSPEEKRLILARLTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVES 299
            .....:||.||::.:...:.....|:.|||.|:|:.||:|.||.|.|:....|::.:....||..
 Frog   200 ELKQESFSTEERKHLARLMLECQEFDHFLATKFSTVKRYGGEGAESMMGFFHEMLKMCAFAGVTD 264

  Fly   300 VIMGMPHRGRLNTLANVCRKPLNQIFTQFAGLEAADDGS---GDVKYHLGTYIERLNRVTNKNIR 361
            :|:|||||||||.|..:.:.|...:|.:..||....:.|   |||..||.:.:: |:..:::.:.
 Frog   265 IIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENSPAIGDVLSHLTSSVD-LDFGSHRPLH 328

  Fly   362 LAVVANPSHLEAVDPVVQGKTRAEQFYRGDQE---------GKKVMSILIHGDAAFCGQGVVYET 417
            :.::.|||||||::||..|||||.|....|.:         |.||:.:.:||||:..|||:|.||
 Frog   329 VTMLPNPSHLEAINPVAVGKTRARQQSVSDGDYSTENSALPGDKVVCLQVHGDASVSGQGIVTET 393

  Fly   418 MHLSDLPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCK 482
            ..||:||.|...|:||::.|||:|:||.....|||.|.:||.::|...:.|||.||||.|:...:
 Frog   394 FTLSNLPHYRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDVGKIVGCAVIHVNGDDPEEVLRATR 458

  Fly   483 VAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAE 547
            :|.|::..|.||.::||:.||:.||||:|||.||.|.||:.||..|:..|:|:::|:|||.:|.|
 Frog   459 LAVEYQRCFRKDIIVDLLCYRQWGHNELDEPFFTNPSMYKIIRSRKSIPDIYSERLVAEGLMTEE 523

  Fly   548 EVKSVAAKYENICEEAFALAKTETHVKYKDWLDSP-------WSGFFEGKDPLKVAPTGVKEETL 605
            |...:...|         .:|...|:........|       |....|....:....|||..:.|
 Frog   524 EASEIRTSY---------YSKLNDHLSSMTLYSPPSTNLQAHWREMVEPSARITTWDTGVPADLL 579

  Fly   606 IHIGNRFSSPPPNAAEFVIHKGLLRVLA-ARKAMVDEKV-ADWALGEAMAFGSLLKEGIHVRLSG 668
            ..||.:....|   .||.:|..||::.| :|...:.|.: .|||..||:||||||.:|.::||||
 Frog   580 KFIGAKSVEVP---EEFQMHSHLLKMHAQSRIQKLQEAIKLDWATAEALAFGSLLCQGFNIRLSG 641

  Fly   669 QDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPY-SVSNSSLSEYAVLGFEHGYSMTNPNA 732
            |||.|||||.||.::..|.... ||..|.||..||..: .||||:|||.||||||:|.|:.:|..
 Frog   642 QDVGRGTFSQRHAMMVCQETSD-TYIPLNHMTSDQKGFLEVSNSALSEEAVLGFEYGMSIESPKL 705

  Fly   733 LVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSD 797
            |.:||||||||.|.||.|.|.|||.|::||:.|||:|:|||||.:|.||||||||:||||||.
 Frog   706 LPIWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPEHSSCRIERFLQMC-- 768

  Fly   798 DPDYFPPESDEFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKS 862
                   :|.|.|| .....|..:.|.:|||.|:|:||||:...||||||:.:||.|||:|.|.|
 Frog   769 -------DSSEEGV-DGDTANMFIVNPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRYPAAVS 825

  Fly   863 PFSEMSEGSEFQRIIPDNGPAGQNPSNVKKVVFCSGRVYYDLTKTRREKQLEG-EIAIVRVEQIS 926
            ...:|:.|..|:.:|   |.:..:|.:|.||:.|||:.||.|.|.|.....:| ..||:|||::.
 Frog   826 SLEDMAPGKTFRPVI---GDSSADPKSVSKVILCSGKHYYALHKQREALGEQGRSFAIIRVEELC 887

  Fly   927 PFPFDLVKEQANLYKNA-ELVWAQEEHKNQGSWTYVQPRF 965
            |||.:.::::.:.|..| :.:|:|||.:|.|:|::|.|||
 Frog   888 PFPLEALQQEIHKYPKAKDFIWSQEEPQNMGAWSFVAPRF 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ogdh	NP_730226.3	SucA	53..1102	CDD:440333	358/949 (38%)
dhtkd1	XP_031754904.1	kgd	106..962	CDD:476867	338/863 (39%)