Protein Alignment Lmpt and RP1

DIOPT Version :9

• Sequence 1: NP_996113.2
• Gene: Lmpt / 39889
• FlyBaseID: FBgn0261565
• Length: 2147
• Species: Drosophila melanogaster
• Sequence 2: XP_016869210.1
• Gene: RP1 / 6101
• HGNCID: 10263
• Length: 2163
• Species: Homo sapiens
• Alignment Length: 2180
• Identity: 386/2180 - (17%)
• Similarity: 694/2180 - (31%)
• Gaps: 794/2180 - (36%)

  Fly   359 QLQASHSKEEADEYAGMEPVVEELCVKKVAPPRFQEPPEEPMVHKVKTQFGQGSGPE-------- 415
            |:.|..|...:..::.:.|...|   .:|.|||... ...|:|.| :..|.:...|:
Human     3 QVSAKMSDTPSTGFSIIHPTSSE---GQVPPPRHLS-LTHPVVAK-RISFYKSGDPQFGGVRVVV 62

  Fly   416 DAYSAKSKTLTFPGVSDEGSSLEPKTPFSIQQSSFSTQPSDEGNRIESERPEPEGEDQI---QEV 477
            :..|.||    |..:.|..|...| .||.::..|                 .|.|...|   :|:
Human    63 NPRSFKS----FDALLDNLSRKVP-LPFGVRNIS-----------------TPRGRHSITRLEEL 105

  Fly   478 QYTEDYLRS---------LDGIKNRP----------------------------------LMRED 499
            :..|.||.|         ||..:.||                                  ....|
Human   106 EDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGD 170

  Fly   500 GSGRRRAFKKRRSSGSSNSSRE--SRASRDEELKMFT-------SLEEEELRHG-----DREDYN 550
            ...||.....||.:.|..:..:  :...:...:|::.       ||:...|..|     .||.:.
Human   171 PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 235

  Fly   551 P-----IKYTSEPTLRVKSHRRHKRSPAK------DVRPTAESTTSLEMLGEESTNPWGEVVPEH 604
            |     .||.....|...|.|.:.:..||      ....::.|.:.:..:..|.|:.     .:.
Human   236 PGNYDIQKYLLPARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHN-----NDC 295

  Fly   605 YKDTEFWKREKALSIDEEEIELER---------PSRGEDVEEEATNEPKSSSFEEATEAQNEQAV 660
            |.|..|        :.|:.:.||:         ||. :|:|       ||..|       |:...
Human   296 YLDYSF--------VPEKYLALEKNDSQNLPIYPSE-DDIE-------KSIIF-------NQDGT 337

  Fly   661 AALKQQLSKEQLDKEAEKDNPQAVDTSDSN---KSNLQTSIAAEEQSRGGSPGLRRSPRMDEMEH 722
            ..::.::.....::|..|.......|..||   ||.:  |.....:||  |.||:.:......:.
Human   338 MTVEMKVRFRIKEEETIKWTTTVSKTGPSNNDEKSEM--SFPGRTESR--SSGLKLAACSFSADV 398

  Fly   723 YPERWSASQEQQSVQQQPPRTAPAINVQQPD-------TAPWR------DQYGLLMEGLSD---- 770
            .|...|::||....::        ||:|..|       :|.|.      |    :::|..|
Human   399 SPMERSSNQEGSLAEE--------INIQMTDQVAETCSSASWENATVDTD----IIQGTQDQAKH 451

  Fly   771 -FYDFTASVNPSRSRSASRNPSPAPKNVANLMDGDTERSLEVYDDTQEGVMAGELNCESVLQLLE 834
             ||               |.|:|..:.|..........:|....:.|| .|.|:.   |..:..|
Human   452 RFY---------------RPPTPGLRRVRQKKSVIGSVTLVSETEVQE-KMIGQF---SYSEERE 497

  Fly   835 SNLNETE---STNDQLQVQTVADDARDGKSILPMV--HEPLESSALGAVLEERGREPSVGRIQSR 894
            |..|::|   .|:...::.:|::     |.:|..:  ::.:|.|:|     ||.:|.|:  ::|.
Human   498 SGENKSEYHMFTHSCSKMSSVSN-----KPVLVQINNNDQMEESSL-----ERKKENSL--LKSS 550

  Fly   895 SRSRSRSPLPTSENLEKSIHKRRERLIKQNDELAERLSHSS--PEDSMEIETSD----------- 946
            :.|.....:.:.:.||.|          .|:.|...:|::|  .||.::....|
Human   551 AISAGVIEITSQKMLEMS----------HNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTY 605

  Fly   947 ---NGRLSPTLEVTLPQPVIEIN------EMADEPMEDAETT--------------------PEE 982
               |.|.||   ::........|      .:::.|..:|.:|                    |:.
Human   606 GNTNDRFSP---ISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKN 667

  Fly   983 MRLFVETLRAERNARSRSRS-RSR---SPLPTAGNIEKSLESRRLKRIQHNDEIFEKLHDQMSSP 1043
            .:..:.::.:::..:||.:: .||   ..|.|.|.:.|:      :||.....|         :.
Human   668 EKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKN------ERINTKGRI---------TK 717

  Fly  1044 QIIIESASPPSLPLPLPTISIEIAEPPEENASHTEAEPEDTPESMARLFEQLRLNRVRS------ 1102
            ::|::.:..|.....|....::.::...|  |:|.....:...::::.|.:.:||..::
Human   718 EMIVQDSDSPLKGGILCEEDLQKSDTVIE--SNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGL 780

  Fly  1103 ----HSRSRSRSPLPTPANLEQSVQKRRERLIAQNDQFFEVLQERARTPEPETRL---TVE---- 1156
                .|||.::..|..|        |:||  |.|.|:.|         |..|::.   |.|
Human   781 LTKRKSRSLNKISLGAP--------KKRE--IGQRDKVF---------PHNESKYCKSTFENKSL 826

  Fly  1157 -YVYEYVQEKDEQVGEGRDKRSLSPSRSRSQSQEKALD---DFHLMLNLEGSELRTLRKNSEELE 1217
             :|:..:::|.:.....:.:..::....|..:::..:.   |.|:       .|::.:|...:..
Human   827 FHVFNILEQKPKDFYAPQSQAEVASGYLRGMAKKSLVSKVTDSHI-------TLKSQKKRKGDKV 884

  Fly  1218 SVLAVGAKQ----REVDMDALEK-------------------LHNANEEIELRVL--SPTNSELE 1257
            ...|:.:||    |...:.:|:|                   |.|.|....|:.:  :|......
Human   885 KASAILSKQHATTRANSLASLKKPDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNET 949

  Fly  1258 RVVEMTREN-----------------PDMDRTVSEVARDLQDELMASGFKRSTYVGESLDLGSDQ 1305
            .||..:..:                 .:.::.::::|....|.|...|.|  :::..  |.|.:.
Human   950 SVVNCSNNSFSGNDPHTNSGKISNFVMESNKHITKIAGLTGDNLCKEGDK--SFIAN--DTGEED 1010

  Fly  1306 FKELRREAAQFQRSRSPSPGSSMDY----AREQAAAQRELQTAILDSLTESRLGAKPKTYSEERT 1366
            ..|.:             .||..|.    ..|.....   |:||.|..|:|.:.|:..  ..|:.
Human  1011 LHETQ-------------VGSLNDAYLVPLHEHCTLS---QSAINDHNTKSHIAAEKS--GPEKK 1057

  Fly  1367 GEFEDISAAQLDDLRHRTAEFQRSRSQSRSPLREVELTQLRDIEAESAKRELQDQLLDRLAASSI 1431
            ..:::|:.|             |.|....:.:      |:..||.|:.|..|...:|.:|.||
Human  1058 LVYQEINLA-------------RKRQSVEAAI------QVDPIEEETPKDLLPVLMLHQLQAS-- 1101

  Fly  1432 NFENFSRHLNADFLDSERRASDSALM--GDMEPDEYHHFRRYSLAQEQPVEEYPSDDYVYISQIE 1494
                         :....:..:..:.  |.:....:|.    ::..        |...:.::.:.
Human  1102 -------------VPGIHKTQNGVVQMPGSLAGVPFHS----AICN--------SSTNLLLAWLL 1141

  Fly  1495 VRTLTGT-RTWLKEDFYTHEPNDFSDSKSPVRDEDSWARAVLAAEAEAAEFDSTNAIYSYDIVGD 1558
            |..|.|: .::.:.|  .|:..:.|.....:.:       :|...|...|.|...|..:
Human  1142 VLNLKGSMNSFCQVD--AHKATNKSSETLALLE-------ILKHIAITEEADDLKAAVA------ 1191

  Fly  1559 HENLDQERSSSNDSEDTRQTVVEIDDEDEFEFELDEGIS----------DNNERTQPTDESHHDT 1613
              ||.:..:|.....:..|.:|.||        |....|          ..|||||.........
Human  1192 --NLVESTTSHFGLSEKEQDMVPID--------LSANCSTVNIQSVPKCSENERTQGISSLDGGC 1246

  Fly  1614 SECEEAERNADRYE-----------NRGAQDWEEVDDVEDFL---DYGFDDGAVGGATPYSDPDS 1664
            |..|.........|           |:.....|..:..:.|.   .||.|..::..|....:..|
Human  1247 SASEACAPEVCVLEVTCSPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCS 1311

  Fly  1665 FIEQIYNEAIKNRKQSGILREYE---TIVQEQLPSDLSE-----SEKEKSGSDSEKYALWAKTRE 1721
            ..:.::::....:|::   ..||   .|.:..:|.::..     :.||.:.:|:     ...|.|
Human  1312 LTDTVFSDKACAQKEN---HTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDN-----LDSTEE 1368

  Fly  1722 LERSHSGTRHSDVDIALGLIPESDHRDSEMRYLGDAHVVARQSTRLRTRYGFNPKL---EVGDL- 1782
            |||.      .|:...|.::.:.::::                       |||..:   .|.:|
Human  1369 LERG------DDIQKDLNILTDPEYKN-----------------------GFNTLVSHQNVSNLS 1404

  Fly  1783 -------EDDIEVDLNYKPKREYNWRKNFRLDDNEEGERSVQVKTEEDEEQEARDQFEEEFGWQD 1840
                   |.:.|:|           :|:..|||.|    :..::..:||........||.
Human  1405 SCGLCLSEKEAELD-----------KKHSSLDDFE----NCSLRKFQDENAYTSFDMEEP----- 1449

  Fly  1841 REQELEEELYQDHEQP------LYANEEN-GEIENVELLENRRISL------GGESITLFSRSPV 1892
                      :..|:|      :.::|.| .|:|:.|.|||....:      |||..|
Human  1450 ----------RTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQAT------- 1497

  Fly  1893 REILPDVPEELPQEEEALEEQPEAVAPLE-------DLPAEK----------------------- 1927
                          ||.::|:.||...||       ::..||
Human  1498 --------------EELIQEEVEASKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFC 1548

  Fly  1928 -PKKKKSKKKLRKGS--------KTEE------------------------ELRDDNDSDTQMGS 1959
             ..|:.|:|:..:|.        ||.|                        :.|.|:||:....:
Human  1549 YDSKQNSEKETNEGETKMVKMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKT 1613

  Fly  1960 SRRSDDQEPTDP-------------------------------------------PKRKTRSRRS 1981
            |  |||  |.|.                                           |......:.|
Human  1614 S--SDD--PNDSGELTQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCS 1674

  Fly  1982 SRSSLTNEEPN--GGSGPFSPRSSLAFVGESLEGIAEFEPQEREE-----------------EQS 2027
            .::||.:.|..  |.|...|..||:         :.||: :||::                 |..
Human  1675 RKASLYDSEGQSFGSSEQVSSSSSM---------LQEFQ-EERQDKCDVSAVRDNYCRGDIVEPG 1729

  Fly  2028 TKKRTKKRKKTSTKE----------CKE------EAKEETQTQAIDDSQLDRALAAALAEIAPVS 2076
            ||:....|..|..:|          .||      .::........|.:.:|..|....:|: |.|
Human  1730 TKQNDDSRILTDIEEGVLIDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEV-PYS 1793

  Fly  2077 VSTNLTPESTHQNLLSTISTGQSVCITPASSIEEI 2111
            ...||.|..|...|.|             |.:||:
Human  1794 HFGNLAPGPTMDELSS-------------SELEEL 1815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmpt	NP_996113.2	GBP_C	<103..201	CDD:303769
		ARGLU	110..255	CDD:291991
		coiled coil	170..181	CDD:293879
		coiled coil	190..201	CDD:293879
RP1	XP_016869210.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900