Protein Alignment Lmpt and Leo1

DIOPT Version :10

• Sequence 1: NP_996113.2
• Gene: Lmpt / 39889
• FlyBaseID: FBgn0261565
• Length: 2147
• Species: Drosophila melanogaster
• Sequence 2: NP_001005548.1
• Gene: Leo1 / 300837
• RGDID: 1549772
• Length: 678
• Species: Rattus norvegicus
• Alignment Length: 789
• Identity: 157/789 - (19%)
• Similarity: 299/789 - (37%)
• Gaps: 253/789 - (32%)

  Fly    52 ADAEELPRMRERLDKQIKEAAER-EALAGTNVMQDGVLYVNGIRV-------DPAGDKRQALAAE 108
            ||.|:|      ...:.:..||| ::.:|::...|.....:|...       |..||..|....|
  Rat     2 ADMEDL------FGSEAESEAERKDSDSGSDSDSDQDNGASGSNASGSESDQDERGDSGQPSNKE 60

  Fly   109 LARQQQIE--------ADTRRQLAEAEAKLVEERLRVQREKEESEEQQRKLVEA----------- 154
            |......|        :|...:.::..::..||| ....:.|.|:..|....||
  Rat    61 LFGDDSEEEGAPHHSGSDNHSEQSDNRSEASEER-SDHEDNEPSDVDQHSGSEAHNDDDDDDDDE 124

  Fly   155 ----ERQRERE---QAEKELQEQREAERRQLEAEENQRKQRENEEKERLENERRLIDAEREREEN 212
                |..|..|   .:|.|..|:.:::..:.:.|:   |..::::.|:|:|..   |.|||:..:
  Rat   125 DDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGED---KSDQSDDDEKLQNSD---DEEREQGSD 183

  Fly   213 ERRLQ---EAEEQREREESERRIVVAERQREQ-AEAEKERAEQQRILAEAEAAQAERRLFDAEIQ 273
            :.:||   :.||:.:..:.|.|..:::..|:| :|.||..::.:|..|             ::..
  Rat   184 DEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAA-------------SDND 235

  Fly   274 RERDQADEEGQALRDAEIVERLLAAERELSPSATESEL-----EEDAAIAEQSRRLISSRTDLEQ 333
            .|:..:|:|.:                   |..::.|.     :|...::::.||    .:|.|:
  Rat   236 EEKQNSDDEDR-------------------PQVSDEEKMQNSDDERPQVSDEDRR----HSDDEE 277

  Fly   334 KQRMIEENARRFLEAEEEMVMLQQRQLQASHSKEEADE------------YAGMEPVV-----EE 381
            :|....|:||. .::|:|::.::::....|.|:.::|.            :.|.:.:.     |:
  Rat   278 EQDQKSESARG-SDSEDEVLRMKRKNAIPSDSEVDSDTEVPKDNNGTMDLFGGADDISSGSDGED 341

  Fly   382 LCVKKVAPPRFQEP-----------PEEPM--------VHKVKTQFGQGSGPEDAYSAKSKTLTF 427
                  .||...:|           .|||:        :.||.|..|     .|.|..|.....
  Rat   342 ------KPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLG-----NDLYFVKLPNFL- 394

  Fly   428 PGVSDEGSSLEPKTPFSIQ--QSSFSTQP--SDEGN-----RIESE-----RPEPEGEDQIQE-- 476
                    |:||: ||..|  :..|..:.  .:||.     ::|:.     |.:.|| ::|:|
  Rat   395 --------SVEPR-PFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEG-NEIKESN 449

  Fly   477 ---VQYTED-------------YLRSLDGIKNRPLMREDGSG--RRRAFKK----RRSSGSSNSS 519
               |::::.             |...|.|..|...:|: |:|  .:..||.    |..|..|.:.
  Rat   450 ARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQ-GTGLQGQAVFKTKLTFRPHSTDSATH 513

  Fly   520 RE------SRASRDEELKMF-----------TSL---EEEELRHGDREDYNPIKYTSEPTLRVKS 564
            |:      .|.|:.:::::.           |.:   |||.||...|.:      :.:..:|.|.
  Rat   514 RKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRE------SQQRRMREKQ 572

  Fly   565 HRRHKRSPAKDVRPTAESTTSLEMLGEESTNPWGEVVPEHYKDTEFWKREKALSIDEEEIELERP 629
            |:|            ..|.:.||              |:.|.:.|  :.|:::|:    ..::..
  Rat   573 HQR------------GLSASYLE--------------PDRYDEEE--EGEESVSL----AAIKNR 605

  Fly   630 SRGEDVEEEATNEPKSSSFEEATEAQNEQAVAALKQQLSKEQLDKEAEKDNPQAVDTSDSNKSNL 694
            .:|...||.|  ...||..:|.:|....|.:...|:..|.|:.:...::   :|.|...:||.:.
  Rat   606 YKGGIREERA--RIYSSDSDEGSEEDKAQRLLKAKKLNSDEEGESSGKR---KAEDDDKANKKHK 665

  Fly   695 QTSIAAEEQ 703
            :..|:.||:
  Rat   666 KYVISDEEE 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmpt	NP_996113.2	Smc	<101..>371	CDD:440809	59/304 (19%)
		PTZ00121	<105..689	CDD:173412	138/712 (19%)
Leo1	NP_001005548.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..373		81/426 (19%)
		MSCRAMM_ClfA	<11..373	CDD:468110	77/411 (19%)
		Leo1	386..548	CDD:461126	34/173 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	559..596		12/70 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	613..678		17/67 (25%)