Protein Alignment Lmpt and Leo1

DIOPT Version :9

• Sequence 1: NP_996113.2
• Gene: Lmpt / 39889
• FlyBaseID: FBgn0261565
• Length: 2147
• Species: Drosophila melanogaster
• Sequence 2: NP_001034611.1
• Gene: Leo1 / 235497
• MGIID: 2685031
• Length: 667
• Species: Mus musculus
• Alignment Length: 794
• Identity: 159/794 - (20%)
• Similarity: 292/794 - (36%)
• Gaps: 274/794 - (34%)

  Fly    52 ADAEELPRMRERLDKQIKEAAER---EALAGTNVMQDGVLYVNGIR----------VDPAGDKRQ 103
            ||.|:|      ...:.:..|||   |:.:.::..||     ||..          .|..||..|
Mouse     2 ADMEDL------FGSEAESEAERKDSESESDSDSDQD-----NGASGSNASGSESDQDDRGDSGQ 55

  Fly   104 ALAAELARQQQIE---------------ADTRRQLAEAEAKLVEERLRVQREKEESEEQQRKLVE 153
            ....||......|               :|.|.:.:|...         ..:.|.|:|.|....|
Mouse    56 PSNKELFGDDSEEEGASHHSGSDNHSERSDNRSEASERSD---------HEDNEPSDEDQHSGSE 111

  Fly   154 AERQREREQAEKELQEQREAERRQLEAEENQRKQRENE-----------EKERLENERRLIDAER 207
            |....:.|      ..:.:...|..|||.:::.|.::|           :.|:|:|..   |.:|
Mouse   112 AHNDDDDE------GHRSDEGSRHSEAEGSEKAQSDDEKWDGEDKSDQSDDEKLQNSD---DEDR 167

  Fly   208 EREENERRLQEA---EEQREREESERRIVVAERQREQ-AEAEKERAEQQRILAEAEAAQAERRLF 268
            |:..:|.:||.:   ||:.:..:.|.|..:::..|:| :|.||..::.:..:|
Mouse   168 EQGSDEDKLQNSDDDEEKMQNTDDEDRAQISDDDRQQLSEEEKGNSDDEHPVA------------ 220

  Fly   269 DAEIQRERDQADEEGQALRDAEIVERLLAAERELSPSATESEL-----EEDAAIAEQSRRLISSR 328
             ::...|:..:|:|.|                   |..::.|.     :|...::::..|    |
Mouse   221 -SDNDEEKQNSDDEDQ-------------------PQVSDEEKMQNSDDERPQVSDEDGR----R 261

  Fly   329 TDLEQKQRMIEENARRFLEAEEEMVMLQQRQLQASHSKEEADE------------YAGMEPVV-- 379
            :|.|::|....|:||. .::|:|::.|:::....|.|:.::|.            :.|.:.:.
Mouse   262 SDGEEEQDQKSESARG-SDSEDEVLRLKRKNAIPSDSEADSDTEVPKDNNGTMDLFGGADDISSG 325

  Fly   380 ---EELCVKKVAPPRFQEP-----------PEEPM--------VHKVKTQFGQGSGPEDAYSAKS 422
               |:      .||...:|           .|||:        :.||.|..|     .|.|..|.
Mouse   326 SDGED------KPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLG-----NDLYFVKL 379

  Fly   423 KTLTFPGVSDEGSSLEPKTPFSIQ--QSSFSTQP--SDEGN-----RIESE-----RPEPEGEDQ 473
            ....         |:||: ||..|  :..|..:.  .:||.     ::|:.     |.:.|| ::
Mouse   380 PNFL---------SVEPR-PFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEG-NE 433

  Fly   474 IQE-----VQYTED-------------YLRSLDGIKNRPLMREDGSG--RRRAFKK----RRSSG 514
            |:|     |::::.             |...|.|..|...:|: |:|  .:..||.    |..|.
Mouse   434 IKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQ-GTGLQGQAVFKTKLTFRPHST 497

  Fly   515 SSNSSRE------SRASRDEELKMF-----------TSL---EEEELRHGDREDYNPIKYTSEPT 559
            .|.:.|:      .|.|:.:::::.           |.:   |||.||...|.:      :.:..
Mouse   498 DSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRE------SQQRR 556

  Fly   560 LRVKSHRRHKRSPAKDVRPTAESTTSLEMLGEESTNPWGEVVPEHYKDTEFWKREKALSIDEEEI 624
            :|.|.|:|            ..|.:.||              |:.|.:.|  :.|:::|:    .
Mouse   557 MREKQHQR------------GLSASYLE--------------PDRYDEEE--EGEESVSL----A 589

  Fly   625 ELERPSRGEDVEEEATNEPKSSSFEEATEAQNEQAVAALKQQLSKEQLDKEAEKDNPQAVDTSDS 689
            .::...:|...||.|  ...||..:|.:|....|.:...|:..|.|:.:...::   :|.|...:
Mouse   590 AIKNRYKGGIREERA--RIYSSDSDEGSEEDKAQRLLKAKKLNSDEEGESSGKR---KAEDDDKA 649

  Fly   690 NKSNLQTSIAAEEQ 703
            ||.:.:..|:.||:
Mouse   650 NKKHKKYVISDEEE 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmpt	NP_996113.2	GBP_C	<103..201	CDD:303769	23/123 (19%)
		ARGLU	110..255	CDD:291991	35/174 (20%)
		coiled coil	170..181	CDD:293879	2/10 (20%)
		coiled coil	190..201	CDD:293879	4/21 (19%)
Leo1	NP_001034611.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..362		83/431 (19%)
		PHA02664	<61..209	CDD:177447	34/165 (21%)
		Leo1	375..533	CDD:281933	33/169 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	548..585		12/70 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	602..667		17/67 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900