DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmpt and Ibsp

DIOPT Version :9

Sequence 1:	NP_996113.2	Gene:	Lmpt / 39889	FlyBaseID:	FBgn0261565	Length:	2147	Species:	Drosophila melanogaster
Sequence 2:	NP_032344.2	Gene:	Ibsp / 15891	MGIID:	96389	Length:	324	Species:	Mus musculus

Alignment Length:	366	Identity:	81/366 - (22%)
Similarity:	127/366 - (34%)	Gaps:	97/366 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   460 RIESERPEPEGEDQIQEVQYTEDYLRSLDGIKNRPLMREDGSGRRRAFKKRRSSGSSNSSRESRA 524
            ||::|..|..|     ..:|...|..........||.|         |..:..|.||..:.:..:
Mouse    25 RIKAEDSEENG-----VFKYRPRYFLYKHAYFYPPLKR---------FPVQGGSDSSEENGDGDS 75

  Fly   525 SRDEELKMFTSLEEEELRHGDREDYNPIKYTSEPTLRVKSHRRHKRSPAKDVRPTAESTTSLEML 589
            |.:|..:..||.|||     :.||       ||..              :|....||::| |..|
Mouse    76 SEEEGEEEETSNEEE-----NNED-------SEGN--------------EDQEAEAENST-LSTL 113

  Fly   590 GEESTNPWGEVVPEHYKDTEFWKREKALSIDEEEIELERPSRGEDVEEEATNEPKSSSFEEATEA 654
            ...:.:...|..|:            |.:.:...::|  |.:..|.|..|   ||....:|..|.
Mouse   114 SGVTASYGAETTPQ------------AQTFELAALQL--PKKAGDAESRA---PKVKESDEEEEE 161

  Fly   655 QNEQAVAALKQQLSKEQLDKEAEKD-NPQAVDTSDSNKSNLQTSIAAEEQSRGGSPGLR-RSPRM 717
            :.|:          :|..::|||.| |..||:.:.:|    .|.:.....|.||..|.. .:...
Mouse   162 EEEE----------EENENEEAEVDENELAVNGTSTN----STEVDGGNGSSGGDNGEEAEAEEA 212

  Fly   718 DEMEHYPERWSASQEQQSVQQQPPRTAPAINVQQPDTAPWRDQYGLLMEGLSDFYDFTASVNPSR 782
            ...|...|..:..:|..||..|   ||..:|..|..|.| .:.||              :.:|..
Mouse   213 SVTEAGAEGTTGGRELTSVGTQ---TAVLLNGFQQTTPP-PEAYG--------------TTSPPI 259

  Fly   783 SRSASRNPSPAPKNVANLMDGDTERSLEVYDDTQEGVMAGE 823
            .:|::.......:...|    :.....||||: :.|...|:
Mouse   260 RKSSTVEYGGEYEQTGN----EYNNEYEVYDN-ENGEPRGD 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmpt	NP_996113.2	GBP_C	<103..201	CDD:303769
		ARGLU	110..255	CDD:291991
		coiled coil	170..181	CDD:293879
		coiled coil	190..201	CDD:293879
Ibsp	NP_032344.2	BSP_II	17..321	CDD:283165	81/366 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	60..228		49/225 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..263		6/34 (18%)
		Cell attachment site. /evidence=ECO:0000255	293..295		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900