Protein Alignment Lmpt and LEO1

DIOPT Version :9

• Sequence 1: NP_996113.2
• Gene: Lmpt / 39889
• FlyBaseID: FBgn0261565
• Length: 2147
• Species: Drosophila melanogaster
• Sequence 2: NP_001310832.1
• Gene: LEO1 / 123169
• HGNCID: 30401
• Length: 688
• Species: Homo sapiens
• Alignment Length: 781
• Identity: 162/781 - (20%)
• Similarity: 298/781 - (38%)
• Gaps: 248/781 - (31%)

  Fly    44 GDSSVDAAADAEE-LPRMRERLDKQIKEAAEREALAGTNVMQDGVLYVNGIRVDPAGDKRQALAA 107
            ||.|.|..|.... .....||.|.: .||:||      :..:|.         ||: |..|...:
Human    63 GDDSEDEGASHHSGSDNHSERSDNR-SEASER------SDHEDN---------DPS-DVDQHSGS 110

  Fly   108 ELARQQQIE---ADTRRQLAEAEAKLVEERLRVQREKEESEEQQRKLVEAERQREREQAEKE-LQ 168
            |.....:.|   :|.....:|||..          ||..|:::     :..|:.:.:|::.| :|
Human   111 EAPNDDEDEGHRSDGGSHHSEAEGS----------EKAHSDDE-----KWGREDKSDQSDDEKIQ 160

  Fly   169 EQREAERRQLEAEENQRKQRENEEKERLENERRLIDAEREREENERRLQEAEEQREREESERRIV 233
            ...:.||.|...|:   |.:.:::.|:::|..   |.||.:..::.|.|.:||::...:.||.:.
Human   161 NSDDEERAQGSDED---KLQNSDDDEKMQNTD---DEERPQLSDDERQQLSEEEKANSDDERPVA 219

  Fly   234 V---AERQREQAEAEKERAEQQRIL----AEAEAAQAERRLFDAEIQRERDQADEEGQALRDAEI 291
            .   .|:|....|.:.:.::::::.    ...:|:..|.|..|.|     ::.|.:.::.|.::.
Human   220 SDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDE-----EEQDHKSESARGSDS 279

  Fly   292 VERLLAAERELSPSATESELEEDAAIAEQSRRL---------ISSRTDLEQKQ----RMIEENAR 343
            .:.:|..:|: :..|::||.:.|..:.:.:...         |||.:|.|.|.    :.::||.
Human   280 EDEVLRMKRK-NAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENG- 342

  Fly   344 RFLEAEEEMVMLQQRQLQASHSKEEADEYAGMEPVVEELCVKKVAPPRFQEPPE---EPMVHKVK 405
                       |.|.|      :||       ||:                 ||   |..:.||.
Human   343 -----------LPQDQ------QEE-------EPI-----------------PETRIEVEIPKVN 366

  Fly   406 TQFGQGSGPEDAYSAKSKTLTFPGVSDEGSSLEPKTPFSIQ--QSSFSTQP--SDEGN-----RI 461
            |..|     .|.|..|.....         |:||: ||..|  :..|..:.  .:||.     ::
Human   367 TDLG-----NDLYFVKLPNFL---------SVEPR-PFDPQYYEDEFEDEEMLDEEGRTRLKLKV 416

  Fly   462 ESE-----RPEPEGEDQIQE-----VQYTED-------------YLRSLDGIKNRPLMREDGSG- 502
            |:.     |.:.|| ::|:|     |::::.             |...|.|..|...:|: |:|
Human   417 ENTIRWRIRRDEEG-NEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQ-GTGL 479

  Fly   503 -RRRAFKK----RRSSGSSNSSRE------SRASRDEELKMF-----------TSL---EEEELR 542
             .:..||.    |..|..|.:.|:      .|.|:.:::::.           |.:   |||.||
Human   480 QGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLR 544

  Fly   543 HGDREDYNPIKYTSEPTLRVKSHRRHKRSPAKDVRPTAESTTSLEMLGEESTNPWGEVVPEHYKD 607
            ...|.:      :.:..:|.|.|:|            ..|.:.||              |:.|.:
Human   545 ASIRRE------SQQRRMREKQHQR------------GLSASYLE--------------PDRYDE 577

  Fly   608 TEFWKREKALSIDEEEIELERPSRGEDVEEEATNEPKSSSFEEATEAQNEQAVAALKQQLSKEQL 672
            .|  :.|:::|:    ..::...:|...||.|  ...||..:|.:|....|.:...|:..|.|:.
Human   578 EE--EGEESISL----AAIKNRYKGGIREERA--RIYSSDSDEGSEEDKAQRLLKAKKLTSDEES 634

  Fly   673 DKEAEKDNPQAVDTSDSNKSNLQTSIAAEEQSRGGSPGLRRSPRMDEMEHYPERWSASQEQQSVQ 737
            .|   ::.|:..:|....|.         |.||.....||::.::    :.|||   .:::..::
Human   635 GK---RERPKLKETWRQWKG---------EVSRPTLSFLRQNRKV----NLPER---EKQKMMIK 680

  Fly   738 Q 738
            |
Human   681 Q 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmpt	NP_996113.2	GBP_C	<103..201	CDD:303769	21/101 (21%)
		ARGLU	110..255	CDD:291991	31/151 (21%)
		coiled coil	170..181	CDD:293879	3/10 (30%)
		coiled coil	190..201	CDD:293879	2/10 (20%)
LEO1	NP_001310832.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..357		79/379 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..583		11/69 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900