DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh4 and opn4xb

DIOPT Version :9

Sequence 1:	NP_476701.1	Gene:	Rh4 / 39887	FlyBaseID:	FBgn0003250	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001245152.1	Gene:	opn4xb / 563080	ZFINID:	ZDB-GENE-070705-526	Length:	460	Species:	Danio rerio

Alignment Length:	345	Identity:	104/345 - (30%)
Similarity:	182/345 - (52%)	Gaps:	22/345 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 QLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL-KAPI 109
            :|:.|..:||::....:.:......||.:|::.|.::|.||:..|.|::||||.|.:|.: ::||
Zfish    10 RLDVPDHVHYIIAFLILIIGTLGVSGNALVMFAFYSNKKLRSLPNYFIMNLAVSDFLMAITQSPI 74

  Fly   110 FIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRNMTFTK--AVIMN 172
            |..|..::.:..|...|:|:|..|:..||.:.:...||..|||.|||||:......:|  ..:..
Zfish    75 FFINCLYKEWMFGELGCKIYAFCGALFGITSMINLLAISIDRYLVITKPLQTIQWNSKRRTGLAI 139

  Fly   173 IIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYYY 237
            :.||||...|.:.||.. |..::|||.:|||::||:|.:...:.:...:..|.|..|..:|||.|
Zfish   140 LCIWLYSLAWSLAPLIG-WSSYIPEGLMTSCTWDYVSPSPANKSYTMMLCCFVFFIPLSIILYCY 203

  Fly   238 SQIVGHVFSHEKALREQAKKMNVESLR--SNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMS 300
                  :|.. .::|:.::.:.:.|.:  |.|.:....:|.::||.|..:..::.:||.||..::
Zfish   204 ------LFMF-LSVRQASRDLEMLSSQKSSFVKQQSMRSEWKLAKIAAVVIVVYVLSWAPYACVT 261

  Fly   301 LIGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWL---------GVNE 356
            |:...|.:.:|||.:..:||...|..|..:||:|||.|.:||..|.:|.|.|         |::.
Zfish   262 LVAWAGHQDVLTPYSKTLPAVLAKSSAIYNPFIYAIIHNKYRATLAERVPGLSCLSRSQKDGLSS 326

  Fly   357 KSGEISSAQSTTTQEQQQTT 376
            .:...:|||.::...|...:
Zfish   327 STNSDASAQDSSVSRQSSVS 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	92/294 (31%)
		TM helix 1	57..81	CDD:320207	4/23 (17%)
		TM helix 2	90..111	CDD:320207	10/21 (48%)
		TM helix 3	127..149	CDD:320207	7/21 (33%)
		TM helix 4	170..186	CDD:320207	5/15 (33%)
		TM helix 5	215..238	CDD:320207	6/22 (27%)
		TM helix 6	279..301	CDD:320207	7/21 (33%)
		TM helix 7	313..338	CDD:320207	10/24 (42%)
opn4xb	NP_001245152.1	7tm_4	26..>229	CDD:304433	65/210 (31%)
opn4xb	NP_001245152.1	7tm_1	35..295	CDD:278431	85/267 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590458
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3623
OMA	1	1.010	-	-		QHG48050
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6356
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24240
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.000