DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh4 and opn6b

DIOPT Version :9

Sequence 1:	NP_476701.1	Gene:	Rh4 / 39887	FlyBaseID:	FBgn0003250	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001303879.1	Gene:	opn6b / 557053	ZFINID:	ZDB-GENE-030616-402	Length:	391	Species:	Danio rerio

Alignment Length:	299	Identity:	74/299 - (24%)
Similarity:	138/299 - (46%)	Gaps:	24/299 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL----KAPIFIYNSFH- 116
            :||:.:.|...|.:|||.||.:.:..:....|.:...||||:.|..:.:    :..:.:::.|.
Zfish    24 IGVYLVILGWLSWIGNGTVILLLTKQRKALEPQDFLTLNLAISDASISIFGYSRGILEVFDVFRD 88

  Fly   117 RGFALGNTW-CQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRNMTFTKAVIMNI-IIWLYC 179
            .|:.:...| |::...:....|:.:..|..||...||.....|.:.:....:.:.:.| .:||:|
Zfish    89 EGYLIKTFWTCKVDGFLILLFGLISINTLTAISVIRYIKGCHPHHAHHINKRNICLVITAVWLFC 153

  Fly   180 TPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDT--RLFVGTIFFFSFVCPTLMILYYYSQIVG 242
            ..|...||.. |..:...||.| |..|:....:..  :|:|..||||:|..|..:|::.|..|:.
Zfish   154 LFWAGAPLLG-WGSYRARGYGT-CEIDWTRALYSIPFKLYVIGIFFFNFFVPLFIIVFAYVSIIR 216

  Fly   243 HVFSHEKALREQAKKMNVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGD 307
            .|.|..|:           |...:|.:.::..|..|.:.::.:|..|.::|:||.|:|:..|.|.
Zfish   217 TVNSSHKS-----------SQGGDVSERQKKIERSITRVSLILCAAFLLAWSPYAVISMWSALGY 270

  Fly   308 KSLLTPGATMIPACTCKLVACIDPFVYAISHPRYRLELQ 346
            :.....|  ::.:...|..:..:||:|.....::|.:||
Zfish   271 QIPTLNG--ILASLFAKSASFYNPFIYIGMSSKFRKDLQ 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	72/296 (24%)
		TM helix 1	57..81	CDD:320207	9/23 (39%)
		TM helix 2	90..111	CDD:320207	5/24 (21%)
		TM helix 3	127..149	CDD:320207	4/21 (19%)
		TM helix 4	170..186	CDD:320207	5/16 (31%)
		TM helix 5	215..238	CDD:320207	9/22 (41%)
		TM helix 6	279..301	CDD:320207	6/21 (29%)
		TM helix 7	313..338	CDD:320207	5/24 (21%)
opn6b	NP_001303879.1	7tm_1	38..295	CDD:278431	66/271 (24%)
opn6b	NP_001303879.1	7tm_4	<204..306	CDD:304433	25/114 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D310934at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920