DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh4 and rgr

DIOPT Version :9

Sequence 1:	NP_476701.1	Gene:	Rh4 / 39887	FlyBaseID:	FBgn0003250	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001016013.1	Gene:	rgr / 548767	XenbaseID:	XB-GENE-1011414	Length:	295	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	75/273 - (27%)
Similarity:	125/273 - (45%)	Gaps:	35/273 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 NGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLKAPIFIYNSFHRGFALGNTWCQIFASIGSYS 136
            ||:.:..|...:.||||||:|:::|||.|..:||.|.:..::||.|.:..|:..|||....|..:
Frog    34 NGLTLLSFYKIRELRTPSNLFIISLAVADTGLCLNAFVAAFSSFLRYWPYGSEGCQIHGFQGFVA 98

  Fly   137 GIGAGMTNAAIGYDRYNVITKPMNRNMTFTKAVIMNIIIWLYCTPWVVLPLTQFWDRFVPEGYLT 201
            .:.:..:.|||.:|||:...  ....:.::.||.:...||.:...|..:||.. |..:..|...|
Frog    99 ALSSIGSCAAIAWDRYHQYC--TRSKLHWSTAVSVVFFIWGFSAFWSAMPLFG-WGEYDYEPLRT 160

  Fly   202 SCSFDYLSD--NFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLR 264
            .|:.||...  |:.:.||  |:.||.|:.|..:::..|..|
Frog   161 CCTLDYSKGDRNYISYLF--TMAFFEFLVPLFILMTAYQSI------------------------ 199

  Fly   265 SNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPACTCKLVACI 329
              ..|.|::.:||. ..::.:..|.| .|.||.::.......|.::|:|...||||...|....:
Frog   200 --YQKMKKSGQIRF-NTSMPVKSLVF-CWGPYCLLCFYAVIQDATILSPKLRMIPALLAKTSPAV 260

  Fly   330 DPFVYAISHPRYR 342
            :.:||.:.:..||
Frog   261 NAYVYGLGNENYR 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	75/273 (27%)
		TM helix 1	57..81	CDD:320207	3/8 (38%)
		TM helix 2	90..111	CDD:320207	9/20 (45%)
		TM helix 3	127..149	CDD:320207	6/21 (29%)
		TM helix 4	170..186	CDD:320207	3/15 (20%)
		TM helix 5	215..238	CDD:320207	7/22 (32%)
		TM helix 6	279..301	CDD:320207	5/21 (24%)
		TM helix 7	313..338	CDD:320207	8/24 (33%)
rgr	NP_001016013.1	7tmA_Retinal_GPR	40..276	CDD:320200	73/267 (27%)
		TM helix 2	51..77	CDD:320200	10/25 (40%)
		TM helix 3	88..118	CDD:320200	10/29 (34%)
		TM helix 4	126..146	CDD:320200	5/19 (26%)
		TM helix 5	173..202	CDD:320200	9/56 (16%)
		TM helix 6	204..234	CDD:320200	8/31 (26%)
		TM helix 7	244..269	CDD:320200	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704940at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010