DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh4 and rrh

DIOPT Version :9

Sequence 1:	NP_476701.1	Gene:	Rh4 / 39887	FlyBaseID:	FBgn0003250	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001004654.1	Gene:	rrh / 447916	ZFINID:	ZDB-GENE-040912-94	Length:	334	Species:	Danio rerio

Alignment Length:	316	Identity:	68/316 - (21%)
Similarity:	145/316 - (45%)	Gaps:	23/316 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 NVPPDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVL 94
            ||..:.: |..:...||.|     |.::..:.|.....|...|.:|:.:|...:.|||.:|..::
Zfish     7 NVSAETV-YGEKSAFTQTE-----HNIVAAYLITAGVISLSSNIVVLLMFVKFRELRTATNAIII 65

  Fly    95 NLAVFDL-IMCLKAPIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKP 158
            |||..|: :..:..|:...:..|..:..|...|||:|::..:.|:.:......:..|||..|.:|
Zfish    66 NLAFTDIGVAGIGYPMSAASDLHGSWKFGYMGCQIYAALNIFFGMASIGLLTVVAIDRYLTICRP 130

  Fly   159 -MNRNMTFTKAVIMNIIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIF 222
             :.:.:|.....::.:..||....|..:|:.. |..:.|:....:|:.::.:::.....:..|:.
Zfish   131 DIGQKLTTRSYTLLIVAAWLNAVFWSSMPIVG-WAGYAPDPTGATCTINWRNNDTSFVSYTMTVI 194

  Fly   223 FFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMN-VESLRSNVDKSKETAEIRIAKAAITIC 286
            ..:|:.|..::.|.|..:        .|..::.|..| ::|:  |:|.|.   ::.:.|.::.:.
Zfish   195 TVNFIIPLSVMFYCYYNV--------SATVKRFKASNCLDSI--NMDWSD---QMDVTKMSVIMI 246

  Fly   287 FLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAISHPRYR 342
            .:|..:|:||.::.|..:|||...:.....:|.....|.....:|.:|.|::.::|
Zfish   247 VMFLAAWSPYSIVCLWASFGDPQKIPAPMAIIAPLLAKSSTFYNPCIYVIANKKFR 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	61/291 (21%)
		TM helix 1	57..81	CDD:320207	5/23 (22%)
		TM helix 2	90..111	CDD:320207	6/21 (29%)
		TM helix 3	127..149	CDD:320207	4/21 (19%)
		TM helix 4	170..186	CDD:320207	3/15 (20%)
		TM helix 5	215..238	CDD:320207	4/22 (18%)
		TM helix 6	279..301	CDD:320207	5/21 (24%)
		TM helix 7	313..338	CDD:320207	5/24 (21%)
rrh	NP_001004654.1	7tm_1	43..294	CDD:278431	56/264 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48050
OrthoDB	1	1.010	-	-		D310934at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.930